| UniProt ID | ZN653_HUMAN | |
|---|---|---|
| UniProt AC | Q96CK0 | |
| Protein Name | Zinc finger protein 653 | |
| Gene Name | ZNF653 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 615 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.. | |
| Protein Sequence | MAERALEPEAEAEAEAGAGGEAAAEEGAAGRKARGRPRLTESDRARRRLESRKKYDVRRVYLGEAHGPWVDLRRRSGWSDAKLAAYLISLERGQRSGRHGKPWEQVPKKPKRKKRRRRNVNCLKNVVIWYEDHKHRCPYEPHLAELDPTFGLYTTAVWQCEAGHRYFQDLHSPLKPLSDSDPDSDKVGNGLVAGSSDSSSSGSASDSEESPEGQPVKAAAAAAAATPTSPVGSSGLITQEGVHIPFDVHHVESLAEQGTPLCSNPAGNGPEALETVVCVPVPVQVGAGPSALFENVPQEALGEVVASCPMPGMVPGSQVIIIAGPGYDALTAEGIHLNMAAGSGVPGSGLGEEVPCAMMEGVAAYTQTEPEGSQPSTMDATAVAGIETKKEKEDLCLLKKEEKEEPVAPELATTVPESAEPEAEADGEELDGSDMSAIIYEIPKEPEKRRRSKRSRVMDADGLLEMFHCPYEGCSQVYVALSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRKNHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTAEVQYNFTCDRCGKRFEKLDSVKFHTLKSHPDHKPT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 82 | Acetylation | RSGWSDAKLAAYLIS CCCCCHHHHHHHHHH | 43.58 | 26051181 | |
| 89 | Phosphorylation | KLAAYLISLERGQRS HHHHHHHHHHCCCCC | 22.91 | 28348404 | |
| 172 | Phosphorylation | RYFQDLHSPLKPLSD HHCCCCCCCCCCCCC | 38.94 | 29449344 | |
| 178 | Phosphorylation | HSPLKPLSDSDPDSD CCCCCCCCCCCCCCC | 43.53 | 20363803 | |
| 180 | Phosphorylation | PLKPLSDSDPDSDKV CCCCCCCCCCCCCCC | 47.90 | 20363803 | |
| 184 | Phosphorylation | LSDSDPDSDKVGNGL CCCCCCCCCCCCCCE | 44.73 | 20363803 | |
| 226 | Phosphorylation | AAAAAAATPTSPVGS HHHHHHCCCCCCCCC | 23.52 | 26074081 | |
| 228 | Phosphorylation | AAAAATPTSPVGSSG HHHHCCCCCCCCCCC | 41.11 | 26074081 | |
| 229 | Phosphorylation | AAAATPTSPVGSSGL HHHCCCCCCCCCCCE | 20.84 | 26074081 | |
| 233 | Phosphorylation | TPTSPVGSSGLITQE CCCCCCCCCCEECCC | 22.82 | 26074081 | |
| 234 | Phosphorylation | PTSPVGSSGLITQEG CCCCCCCCCEECCCC | 31.52 | 26074081 | |
| 238 | Phosphorylation | VGSSGLITQEGVHIP CCCCCEECCCCEECC | 26.13 | 26074081 | |
| 523 | Phosphorylation | RRHMIIHSGVREFTC HHHCEEECCCCEEEC | 28.68 | - | |
| 551 | Phosphorylation | EVHRRTHTGETPLQC EEEECCCCCCCCEEE | 35.78 | 28555341 | |
| 579 | Phosphorylation | NWHMKKHTAEVQYNF CCCHHCCEEEEEEEE | 33.13 | 28555341 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZN653_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZN653_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZN653_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ZN653_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
