ZN629_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN629_HUMAN
• UniProt AC: Q9UEG4
• Protein Name: Zinc finger protein 629
• Gene Name: ZNF629
• Organism: Homo sapiens (Human).
• Sequence Length: 869
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEPETALWGPDLQGPEQSPNDAHRGAESENEEESPRQESSGEEIIMGDPAQSPESKDSTEMSLERSSQDPSVPQNPPTPLGHSNPLDHQIPLDPPAPEVVPTPSDWTKACEASWQWGALTTWNSPPVVPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAPKPPQLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCHPGVSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MEPETALWGPDL ---CCCCCCCCCCCC	37.45	23186163
18	Phosphorylation	DLQGPEQSPNDAHRG CCCCCCCCCCCCCCC	24.82	25159151
28	Phosphorylation	DAHRGAESENEEESP CCCCCCCCCCCCCCC	45.23	23401153
34	Phosphorylation	ESENEEESPRQESSG CCCCCCCCCCCCCCC	28.76	23927012
39	Phosphorylation	EESPRQESSGEEIIM CCCCCCCCCCCCCCC	34.99	28348404
40	Phosphorylation	ESPRQESSGEEIIMG CCCCCCCCCCCCCCC	49.85	28348404
52	Phosphorylation	IMGDPAQSPESKDST CCCCCCCCCCCCCCC	32.51	28348404
55	Phosphorylation	DPAQSPESKDSTEMS CCCCCCCCCCCCCCC	45.18	29978859
58	Phosphorylation	QSPESKDSTEMSLER CCCCCCCCCCCCHHH	29.97	21815630
62	Phosphorylation	SKDSTEMSLERSSQD CCCCCCCCHHHHCCC	22.35	28674419
66	Phosphorylation	TEMSLERSSQDPSVP CCCCHHHHCCCCCCC	23.99	25002506
67	Phosphorylation	EMSLERSSQDPSVPQ CCCHHHHCCCCCCCC	44.84	25002506
71	Phosphorylation	ERSSQDPSVPQNPPT HHHCCCCCCCCCCCC	55.51	25002506
78	Phosphorylation	SVPQNPPTPLGHSNP CCCCCCCCCCCCCCC	32.19	25002506
83	Phosphorylation	PPTPLGHSNPLDHQI CCCCCCCCCCCCCCC	38.04	25002506
120	Phosphorylation	SWQWGALTTWNSPPV HEECCCCCCCCCCCC	29.27	28348404
121	Phosphorylation	WQWGALTTWNSPPVV EECCCCCCCCCCCCC	24.41	28348404
124	Phosphorylation	GALTTWNSPPVVPAN CCCCCCCCCCCCCCC	23.34	28348404
148	Acetylation	GRPAGAEKPYICNEC CCCCCCCCCEECCCC	42.46	26051181
173	Phosphorylation	LRHQRIHTGERPNTC HHHCCCCCCCCCCCH	38.06	28655764
186	Phosphorylation	TCSECGKSFTQSSHL CHHHCCCCHHHHHHH	20.86	28555341
188	Phosphorylation	SECGKSFTQSSHLVQ HHCCCCHHHHHHHHH	34.33	28555341
190	Phosphorylation	CGKSFTQSSHLVQHQ CCCCHHHHHHHHHCC	19.37	28555341
191	Phosphorylation	GKSFTQSSHLVQHQR CCCHHHHHHHHHCCC	15.83	28555341
199	Phosphorylation	HLVQHQRTHTGEKPY HHHHCCCCCCCCCCC	19.74	28348404
201	Phosphorylation	VQHQRTHTGEKPYKC HHCCCCCCCCCCCCC	46.56	26270265
204	Ubiquitination	QRTHTGEKPYKCPDC CCCCCCCCCCCCCCC	55.80	-
227	Phosphorylation	NLVQHQRTHTGEKPY CHHCCCCCCCCCCCC	19.74	28348404
229	Phosphorylation	VQHQRTHTGEKPYKC HCCCCCCCCCCCCCC	46.56	26270265
232	Ubiquitination	QRTHTGEKPYKCTEC CCCCCCCCCCCCCHH	55.80	-
237	Ubiquitination	GEKPYKCTECEKAFT CCCCCCCCHHHHHHH	39.25	32142685
246	Phosphorylation	CEKAFTQSTNLIKHQ HHHHHHHCCCHHHHC	19.06	28555341
251	Sumoylation	TQSTNLIKHQRSHTG HHCCCHHHHCCCCCC	36.53	28112733
251	Ubiquitination	TQSTNLIKHQRSHTG HHCCCHHHHCCCCCC	36.53	32142685
257	Phosphorylation	IKHQRSHTGEKPYKC HHHCCCCCCCCCCCC	48.56	24719451
274	Ubiquitination	CRRAFYRSSDLIQHQ HHHHHHHCHHHHHHC	19.47	33845483
283	Phosphorylation	DLIQHQATHTGEKPY HHHHHCCCCCCCCCC	17.25	29214152
285	Phosphorylation	IQHQATHTGEKPYKC HHHCCCCCCCCCCCC	42.56	25159151
288	Ubiquitination	QATHTGEKPYKCPEC CCCCCCCCCCCCCCH	55.80	33845483
326	Phosphorylation	RCTECGKSFIQSSEL ECCCCCCHHHHHHHC	16.93	28555341
339	Phosphorylation	ELTQHQRTHTGEKPY HCCCCCCCCCCCCCE	19.74	28152594
341	Phosphorylation	TQHQRTHTGEKPYEC CCCCCCCCCCCCEEH	46.56	28152594
346	Phosphorylation	THTGEKPYECLECGK CCCCCCCEEHHHCCC	30.27	28152594
349	Ubiquitination	GEKPYECLECGKSFG CCCCEEHHHCCCCCC	4.00	23000965
359	Phosphorylation	GKSFGHSSTLIKHQR CCCCCCHHHHHHHHH	22.89	28555341
363	Ubiquitination	GHSSTLIKHQRTHLR CCHHHHHHHHHHHCC	36.48	23000965
382	Phosphorylation	KCPVCGKTFTLSATL CCCCCCCEEEEEHHH	13.72	20068231
384	Phosphorylation	PVCGKTFTLSATLLR CCCCCEEEEEHHHHH	25.65	20068231
386	Phosphorylation	CGKTFTLSATLLRHQ CCCEEEEEHHHHHCC	19.02	-
410	Phosphorylation	KCPECGKSFSVSSNL CCCCCCCEEEECCHH	14.19	28555341
438	Phosphorylation	ICADCGKSFIMSSTL EECCCCCCHHHCHHH	12.80	28555341
442	Phosphorylation	CGKSFIMSSTLIRHQ CCCCHHHCHHHHHCC	18.50	28555341
443	Phosphorylation	GKSFIMSSTLIRHQR CCCHHHCHHHHHCCC	15.17	28555341
453	Phosphorylation	IRHQRIHTGEKPYKC HHCCCCCCCCCCEEC	44.67	29496963
471	Phosphorylation	GKSFIRSSHLIQHRR CHHHHHHHHHHHCCC	16.68	28555341
479	Phosphorylation	HLIQHRRTHTGEKPY HHHHCCCCCCCCCCC	24.60	28348404
481	Phosphorylation	IQHRRTHTGEKPYKC HHCCCCCCCCCCCCC	46.56	26270265
484	Ubiquitination	RRTHTGEKPYKCPEC CCCCCCCCCCCCCCC	55.80	-
494	Phosphorylation	KCPECGKSFSQSSNL CCCCCCCCCCCCCCH	18.53	28555341
550	Phosphorylation	ARRAQGDSLLGLGDP HHHCCCCCCCCCCCH	32.11	21712546
558	Phosphorylation	LLGLGDPSLLTPPPG CCCCCCHHHCCCCCC	40.53	22199227
561	Phosphorylation	LGDPSLLTPPPGAKP CCCHHHCCCCCCCCC	38.76	22199227
570	Ubiquitination	PPGAKPHKCLVCGKG CCCCCCCEEEEECCC	37.48	-
597	Phosphorylation	IHIGENPYKNADGLI EECCCCCCCCCCCCC	28.58	-
616	Phosphorylation	PKPPQLRSPRLPFRG CCCCCCCCCCCCCCC	23.98	26055452
618	Methylation	PPQLRSPRLPFRGNS CCCCCCCCCCCCCCC	57.13	115920545
622	Methylation	RSPRLPFRGNSYPGA CCCCCCCCCCCCCCC	41.25	115920549
625	Phosphorylation	RLPFRGNSYPGAAEG CCCCCCCCCCCCCCC	35.21	28102081
626	Phosphorylation	LPFRGNSYPGAAEGR CCCCCCCCCCCCCCC	15.08	29214152
628	Ubiquitination	FRGNSYPGAAEGRAE CCCCCCCCCCCCCCC	29.23	33845483
642	Ubiquitination	EAPGQPLKPPEGQEG CCCCCCCCCCCCCCC	66.27	33845483
651	Phosphorylation	PEGQEGFSQRRGLLS CCCCCCCCHHHCCCC	33.37	28555341
688	Sumoylation	QLTHGNEKPFLFPDY HCCCCCCCCCCCCCC	45.10	28112733
706	Phosphorylation	LGEGAGPSPFLSGKP CCCCCCCCCCCCCCC	27.63	27050516
712	Acetylation	PSPFLSGKPFKCPEC CCCCCCCCCCCCCHH	43.86	26051181
731	Phosphorylation	GLSSELLLHQKVHAG CCCHHHHHHCHHHCC	6.68	33259812
741	Phosphorylation	KVHAGGKSSQKSPEL HHHCCCCCCCCCCCC	41.08	29396449
742	Phosphorylation	VHAGGKSSQKSPELG HHCCCCCCCCCCCCC	45.15	29396449
745	Phosphorylation	GGKSSQKSPELGKSS CCCCCCCCCCCCCCH	18.90	21955146
750	Sumoylation	QKSPELGKSSSVLLE CCCCCCCCCHHHHHH	60.84	28112733
751	Phosphorylation	KSPELGKSSSVLLEH CCCCCCCCHHHHHHH	26.50	23312004
752	Phosphorylation	SPELGKSSSVLLEHL CCCCCCCHHHHHHHH	28.14	23312004
753	Phosphorylation	PELGKSSSVLLEHLR CCCCCCHHHHHHHHC	24.71	23312004
761	Phosphorylation	VLLEHLRSPLGARPY HHHHHHCCCCCCCCC	30.73	29978859
780	Methylation	CRASFLDRVALTRHQ HHHHHHHHHHHHHCC	20.11	115920553
840	Sumoylation	PKTLVEEKPYLCPEC CCCCCCCCCCCCCCC	26.00	28112733
868	Phosphorylation	RSCHPGVSL------ HHCCCCCCC------	33.99	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN629_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN629_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN629_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN629_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.