ZN624_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN624_HUMAN
• UniProt AC: Q9P2J8
• Protein Name: Zinc finger protein 624
• Gene Name: ZNF624
• Organism: Homo sapiens (Human).
• Sequence Length: 865
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MSLQDSTLSREGKPEGEIMAAVFFSVGRLSPEVTQPDEDLHLQAEETQLVKESVTFKDVAIDFTLEEWRLMDPTQRNLHKDVMLENYRNLVSLGLAVSKPDMISHLENGKGPWVTVREISRIPYPDMEPKPATKKATRTKAISEDLSQEAILEKLTENGLWDSRMEGLWKWNDRILRLQNNQENHLSQRIIPLKKTPTSQRGFRFESILIPEPGIATEELHSRCQTQEENFTENLNLITDTHLGKIICKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSSLIVHIRTHTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQRIHQRETQLI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	FFSVGRLSPEVTQPD EEECCCCCCCCCCCC	20.04	25849741
34	Phosphorylation	GRLSPEVTQPDEDLH CCCCCCCCCCCCCCC	32.49	30266825
140	Ubiquitination	TKKATRTKAISEDLS CCHHHHHHHHCCCCC	40.19	29967540
147	Phosphorylation	KAISEDLSQEAILEK HHHCCCCCHHHHHHH	37.99	-
154	Ubiquitination	SQEAILEKLTENGLW CHHHHHHHHHHCCCC	58.21	29967540
252	Acetylation	KIICKEMKGSKAIRQ HHHHHHCCCCHHHHH	62.21	11921557
267	Acetylation	TSELTLGKKSNNKEK HCCCCCCCCCCCCCC	57.02	11921565
279	Phosphorylation	KEKPYKCSTCEKAFH CCCCCCCCCHHHHHH	31.76	-
302	Ubiquitination	QRTHTKEKPYECNEC CCCCCCCCCCCCCCC	55.23	-
324	Ubiquitination	SYLSQHKKIHTGEKP HHHHHCCCCCCCCCC	37.28	-
327	Phosphorylation	SQHKKIHTGEKPYKC HHCCCCCCCCCCCCC	50.97	29496963
332	Phosphorylation	IHTGEKPYKCNECGK CCCCCCCCCCCCCCC	38.96	18767875
333	Sumoylation	HTGEKPYKCNECGKA CCCCCCCCCCCCCCE	38.83	-
333	Sumoylation	HTGEKPYKCNECGKA CCCCCCCCCCCCCCE	38.83	-
383	Phosphorylation	NQHQRIQTGEKPYKC CCCCCCCCCCCCCCC	44.96	22210691
391	Phosphorylation	GEKPYKCSECGKAFS CCCCCCCCCCCCCCC	31.59	22210691
398	Phosphorylation	SECGKAFSDKSKLAR CCCCCCCCCHHHHHH	49.33	-
401	Phosphorylation	GKAFSDKSKLARHQE CCCCCCHHHHHHCCH	37.58	-
467	Phosphorylation	NVHQRIHTGEKPFRC EEECCCCCCCCCEEE	44.67	29496963
493	Phosphorylation	SLIVHIRTHTGEKPY CEEEEEEECCCCCCE	24.16	28348404
495	Phosphorylation	IVHIRTHTGEKPYEC EEEEEECCCCCCEEC	46.56	29496963
498	Ubiquitination	IRTHTGEKPYECNEC EEECCCCCCEECCHH	55.00	-
523	Phosphorylation	TEHQRIHTGEKPYKC CCCCCCCCCCCCCCC	44.67	29496963
528	Phosphorylation	IHTGEKPYKCNECGK CCCCCCCCCCCCCCC	38.96	18767875
529	Sumoylation	HTGEKPYKCNECGKA CCCCCCCCCCCCCCE	38.83	-
529	Sumoylation	HTGEKPYKCNECGKA CCCCCCCCCCCCCCE	38.83	-
568	Phosphorylation	CGKAFMRSSSLIIHQ HHHHHHHCCCEEEEE	16.70	23186163
569	Phosphorylation	GKAFMRSSSLIIHQR HHHHHHCCCEEEEEE	20.85	23186163
570	Phosphorylation	KAFMRSSSLIIHQRI HHHHHCCCEEEEEEE	25.49	25106551
607	Phosphorylation	TVHQRIHTGEKPYKC EEECEECCCCCCCCC	44.67	29496963
661	Phosphorylation	YLIVHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	28348404
663	Phosphorylation	IVHQRTHTGEKPYKC EEEECCCCCCCCEEC	46.56	26270265
666	Ubiquitination	QRTHTGEKPYKCNEC ECCCCCCCCEECCHH	55.80	-
691	Phosphorylation	TVHQRRHTGEKPYKC EEECCCCCCCCCEEC	45.27	23532336
697	Sumoylation	HTGEKPYKCNECGKV CCCCCCEECCCCCCE	38.83	-
697	Sumoylation	HTGEKPYKCNECGKV CCCCCCEECCCCCCE	38.83	-
717	Phosphorylation	GFNTHQRTHTGEKPF CCCCCCCCCCCCCCE	19.74	23312004
719	Phosphorylation	NTHQRTHTGEKPFKC CCCCCCCCCCCCEEC	46.56	29496963
747	Phosphorylation	TEHQKIHSGEKPYKC ECCCCCCCCCCCEEC	52.71	29496963
773	Phosphorylation	YLTVHWRTHTGEKPY EEEEEEEECCCCCCE	20.71	-
775	Phosphorylation	TVHWRTHTGEKPYTC EEEEEECCCCCCEEC	46.56	-
803	Phosphorylation	TLHQRIHTGERPYKC HHHCCHHCCCCCEEC	38.06	24719451
809	Ubiquitination	HTGERPYKCEECGKA HCCCCCEECCCCCCE	37.54	-
809	Sumoylation	HTGERPYKCEECGKA HCCCCCEECCCCCCE	37.54	-
809	Sumoylation	HTGERPYKCEECGKA HCCCCCEECCCCCCE	37.54	-
837	Sumoylation	HTGEKPYKCNECGKA ECCCCCEEECCCCHH	38.83	-
837	Sumoylation	HTGEKPYKCNECGKA ECCCCCEEECCCCHH	38.83	-
847	Phosphorylation	ECGKAFRSSSSLTVH CCCHHHHCCCCCCHH	28.28	29116813
848	Phosphorylation	CGKAFRSSSSLTVHQ CCHHHHCCCCCCHHH	21.49	29116813
849	Phosphorylation	GKAFRSSSSLTVHQR CHHHHCCCCCCHHHH	30.52	30177828
850	Phosphorylation	KAFRSSSSLTVHQRI HHHHCCCCCCHHHHH	29.97	30177828
852	Phosphorylation	FRSSSSLTVHQRIHQ HHCCCCCCHHHHHHH	20.21	30177828

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN624_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN624_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN624_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN624_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.