ZN606_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN606_HUMAN
• UniProt AC: Q8WXB4
• Protein Name: Zinc finger protein 606
• Gene Name: ZNF606
• Organism: Homo sapiens (Human).
• Sequence Length: 792
• Subcellular Localization: Nucleus .
• Protein Description: May act as a transcriptional repressor..
• Protein Sequence: MAAINPWASWGALTDQSWGMTAVDPWASWALCPQYPAWHVEGSLEEGRRATGLPAAQVQEPVTFKDVAVDFTQEEWGQLDLVQRTLYRDVMLETYGHLLSVGNQIAKPEVISLLEQGEEPWSVEQACPQRTCPEWVRNLESKALIPAQSIFEEEQSHGMKLERYIWDDPWFSRLEVLGCKDQLEMYHMNQSTAMRQMVFMQKQVLSQRSSEFCGLGAEFSQNLNFVPSQRVSQIEHFYKPDTHAQSWRCDSAIMYADKVTCENNDYDKTVYQSIQPIYPARIQTGDNLFKCTDAVKSFNHIIHFGDHKGIHTGEKLYEYKECHQIFNQSPSFNEHPRLHVGENQYNYKEYENIFYFSSFMEHQKIGTVEKAYKYNEWEKVFGYDSFLTQHTSTYTAEKPYDYNECGTSFIWSSYLIQHKKTHTGEKPYECDKCGKVFRNRSALTKHERTHTGIKPYECNKCGKAFSWNSHLIVHKRIHTGEKPYVCNECGKSFNWNSHLIGHQRTHTGEKPFECTECGKSFSWSSHLIAHMRMHTGEKPFKCDECEKAFRDYSALSKHERTHSGAKPYKCTECGKSFSWSSHLIAHQRTHTGEKPYNCQECGKAFRERSALTKHEIIHSGIKPYECNKCGKSCSQMAHLVRHQRTHTGEKPYECNKCGKSFSQSCHLVAHRRIHTGEKPYKCNQCERSFNCSSHLIAHRRTHTGEKPYRCNECGKAFNESSSLIVHLRNHTGEKPYKCNHCEKAFCKNSSLIIHQRMHSGEKRFICSECGKAFSGHSALLQHQRNHSEEKLN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	LEEGRRATGLPAAQV HHHHHHCCCCCHHHC	37.12	23312004
63	Phosphorylation	AQVQEPVTFKDVAVD HHCCCCCEECEEEEE	35.37	23312004
232	Phosphorylation	FVPSQRVSQIEHFYK CCCCCCCHHEEEECC	27.85	29978859
238	Phosphorylation	VSQIEHFYKPDTHAQ CHHEEEECCCCCCCC	24.42	29978859
242	Phosphorylation	EHFYKPDTHAQSWRC EEECCCCCCCCCCCC	27.86	29978859
246	Phosphorylation	KPDTHAQSWRCDSAI CCCCCCCCCCCCCEE	19.78	29978859
441	Phosphorylation	GKVFRNRSALTKHER CCEEECCCCCCCCCC	31.05	21118733
444	Phosphorylation	FRNRSALTKHERTHT EECCCCCCCCCCCCC	30.03	27251275
449	Phosphorylation	ALTKHERTHTGIKPY CCCCCCCCCCCCCCE	22.32	27251275
451	Phosphorylation	TKHERTHTGIKPYEC CCCCCCCCCCCCEEC	39.73	27251275
479	Phosphorylation	IVHKRIHTGEKPYVC EEEEEEECCCCCEEC	44.67	20736484
505	Phosphorylation	HLIGHQRTHTGEKPF HHCCCCCCCCCCCCE	19.74	-
507	Phosphorylation	IGHQRTHTGEKPFEC CCCCCCCCCCCCEEC	46.56	-
541	Sumoylation	HTGEKPFKCDECEKA HCCCCCCCCHHHHHH	49.67	-
541	Sumoylation	HTGEKPFKCDECEKA HCCCCCCCCHHHHHH	49.67	-
542	S-palmitoylation	TGEKPFKCDECEKAF CCCCCCCCHHHHHHH	5.65	29575903
545	S-palmitoylation	KPFKCDECEKAFRDY CCCCCHHHHHHHHCH	4.08	29575903
589	Phosphorylation	HLIAHQRTHTGEKPY CHHEECCCCCCCCCC	19.74	-
591	Phosphorylation	IAHQRTHTGEKPYNC HEECCCCCCCCCCCH	46.56	-
645	Phosphorylation	HLVRHQRTHTGEKPY HHHHHCCCCCCCCCC	19.74	-
647	Phosphorylation	VRHQRTHTGEKPYEC HHHCCCCCCCCCCCC	46.56	-
675	Phosphorylation	VAHRRIHTGEKPYKC EEECCCCCCCCCCCC	44.67	29496963
701	Phosphorylation	HLIAHRRTHTGEKPY CHHCCCCCCCCCCCE	24.60	-
703	Phosphorylation	IAHRRTHTGEKPYRC HCCCCCCCCCCCEEC	46.56	24719451
706	Acetylation	RRTHTGEKPYRCNEC CCCCCCCCCEECCCC	49.01	7987847
721	Phosphorylation	GKAFNESSSLIVHLR HHHHHCCCCEEEECC	24.00	-
722	Phosphorylation	KAFNESSSLIVHLRN HHHHCCCCEEEECCC	31.24	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN606_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN606_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN606_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN606_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.