ZN605_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN605_HUMAN
• UniProt AC: Q86T29
• Protein Name: Zinc finger protein 605
• Gene Name: ZNF605
• Organism: Homo sapiens (Human).
• Sequence Length: 641
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MIQSQISFEDVAVDFTLEEWQLLNPTQKNLYRDVMLENYSNLVFLEVWLDNPKMWLRDNQDNLKSMERGHKYDVFGKIFNSSINIVHVGLRSHKCGTGEKSLKCPFDLLIPKNNCERKKIDELNKKLLFCIKPGRTHGGIKYCDCSTCRKSSNEEPWLTANHITHTGVYLCMECGRFFNKKSQLVIHQRTHTGEKPYQCSECGKAFSQKSLLTVHQRTHSGEKPHGCSECQKAFSRKSLLILHQRIHTGEKPYGCSECGKAFSRKSQLKRHQITHTIEKPYSCSECGKAFSQKLKLITHQRAHTGEKPYPCSHCGKAFFWKSQLITHQRTHTGKKPYGCGECQKAFSRNSLLIRHQRIHTGEKPYECNECGEAFIRKPQLIKHQITHTGEKNYRCSDCEEAFFKKSELIRHQKIHLGEKPYGCIQCGKTFFGKSQLLTHHRTHTGEKPYECSECGKAFTQKSSLISHQRTHTGEKPYECSECRKTFSEKSSLIHHQRTHTGEKPFECSECRKAFAWKPQLLRHQRIHTGEKPYECSECGKAFVQKVQLIKHQRNHTGEKTYGCSDCAKAFFEKAQLIIHQRIHTGERPYKCGECGKSFTRKSHLMRHQRIHTGDKYYGCNECGTTFNRKSQLMIHQRNHII

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MIQSQISFEDV ----CCCCCCCHHHE	20.68	24043423
7	Phosphorylation	-MIQSQISFEDVAVD -CCCCCCCHHHEEEE	18.23	24043423
16	Phosphorylation	EDVAVDFTLEEWQLL HHEEEEEEHHHHHHC	28.88	24043423
26	Phosphorylation	EWQLLNPTQKNLYRD HHHHCCCCCCHHHHH	51.61	24043423
72	Phosphorylation	SMERGHKYDVFGKIF HHHHHCCCCHHHHHH	16.21	25002506
81	Phosphorylation	VFGKIFNSSINIVHV HHHHHHHCCCCEEEE	23.11	30257219
82	Phosphorylation	FGKIFNSSINIVHVG HHHHHHCCCCEEEEE	22.28	30257219
190	Phosphorylation	QLVIHQRTHTGEKPY CEEEEECCCCCCCCE	19.74	28111955
192	Phosphorylation	VIHQRTHTGEKPYQC EEEECCCCCCCCEEC	46.56	28111955
195	Acetylation	QRTHTGEKPYQCSEC ECCCCCCCCEECCCC	50.82	11566399
195	Sumoylation	QRTHTGEKPYQCSEC ECCCCCCCCEECCCC	50.82	-
195	Ubiquitination	QRTHTGEKPYQCSEC ECCCCCCCCEECCCC	50.82	-
195	Sumoylation	QRTHTGEKPYQCSEC ECCCCCCCCEECCCC	50.82	-
197	Phosphorylation	THTGEKPYQCSECGK CCCCCCCEECCCCCH	32.97	28111955
204	Ubiquitination	YQCSECGKAFSQKSL EECCCCCHHHCCCCE	58.90	-
210	Phosphorylation	GKAFSQKSLLTVHQR CHHHCCCCEEEEECC	22.45	27251275
213	Phosphorylation	FSQKSLLTVHQRTHS HCCCCEEEEECCCCC	22.64	27251275
248	Phosphorylation	ILHQRIHTGEKPYGC EEEHHHHCCCCCCCC	44.67	28111955
260	Ubiquitination	YGCSECGKAFSRKSQ CCCCHHHHHHCCHHH	58.90	-
360	Phosphorylation	IRHQRIHTGEKPYEC EEEEEECCCCCCCCC	44.67	28655764
386	Phosphorylation	QLIKHQITHTGEKNY HHHEEECCCCCCCCC	13.55	-
442	Phosphorylation	QLLTHHRTHTGEKPY HHHHCCCCCCCCCCE	21.31	-
444	Phosphorylation	LTHHRTHTGEKPYEC HHCCCCCCCCCCEEC	46.56	-
447	Ubiquitination	HRTHTGEKPYECSEC CCCCCCCCCEECCCC	55.00	-
452	Phosphorylation	GEKPYECSECGKAFT CCCCEECCCCCCCHH	24.79	-
470	Phosphorylation	SLISHQRTHTGEKPY HHHCCCCCCCCCCCC	19.74	-
472	Phosphorylation	ISHQRTHTGEKPYEC HCCCCCCCCCCCCCC	46.56	-
498	Phosphorylation	SLIHHQRTHTGEKPF HHHEECCCCCCCCCC	19.74	-
500	Phosphorylation	IHHQRTHTGEKPFEC HEECCCCCCCCCCCC	46.56	-
528	Phosphorylation	LRHQRIHTGEKPYEC HHCCCCCCCCCCCCC	44.67	29496963
533	Phosphorylation	IHTGEKPYECSECGK CCCCCCCCCCCHHHH	40.41	-
536	Phosphorylation	GEKPYECSECGKAFV CCCCCCCCHHHHHHH	24.79	27251275
584	Phosphorylation	IIHQRIHTGERPYKC HEECCCCCCCCCEEC	38.06	24719451
590	Sumoylation	HTGERPYKCGECGKS CCCCCCEECCCCCCC	38.15	-
590	Sumoylation	HTGERPYKCGECGKS CCCCCCEECCCCCCC	38.15	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN605_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN605_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN605_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN605_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.