ZN599_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN599_HUMAN
• UniProt AC: Q96NL3
• Protein Name: Zinc finger protein 599
• Gene Name: ZNF599
• Organism: Homo sapiens (Human).
• Sequence Length: 588
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAAPALALVSFEDVVVTFTGEEWGHLDLAQRTLYQEVMLETCRLLVSLGHPVPKPELIYLLEHGQELWTVKRGLSQSTCAGEKAKPKITEPTASQLAFSEESSFQELLAQRSSRDSRLGQARDEEKLIKIQEGNLRPGTNPHKEICPEKLSYKHDDLEPDDSLGLRVLQERVTPQDALHECDSQGPGKDPMTDARNNPYTCTECGKGFSKKWALVRHQQIHAGVKPYECNECGKACRYMADVIRHMRLHTGEKPYKCIECGKAFKRRFHLTEHQRIHTGDKPYECKECGKAFTHRSSFIQHNMTHTREKPFLCKECGKAFYYSSSFAQHMRIHTGKKLYECGECGKAFTHRSTFIQHNVTHTGEKPFLCKECGKTFCLNSSFTQHMRIHTGEKPYECGECGKAFTHRSTFIRHKRTHTGEKPFECKECGKAFCDSSSLIQHMRIHTGEKPYECSECGKAFTHHSVFIRHNRTHSGQKPLECKECAKAFYYSSSFTRHMRIHTGEKPYVCRECGKAFTQPANFVRHNRIHTGEKPFECKECEKAFCDNFALTQHMRTHTGEKPFECNECGKTFSHSSSFTHHRKIHTRV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	VPKPELIYLLEHGQE CCCHHHEEHHCCCCE	20.19	25884760
216	Ubiquitination	SKKWALVRHQQIHAG CCCCHHHHHHHCCCC	23.81	21890473
250	Phosphorylation	IRHMRLHTGEKPYKC HHHHHHCCCCCCEEE	52.18	27422710
253	Sumoylation	MRLHTGEKPYKCIEC HHHCCCCCCEEEEEC	55.80	-
253	Ubiquitination	MRLHTGEKPYKCIEC HHHCCCCCCEEEEEC	55.80	21890473
253	Sumoylation	MRLHTGEKPYKCIEC HHHCCCCCCEEEEEC	55.80	-
278	Phosphorylation	TEHQRIHTGDKPYEC CCCCEECCCCCCCCC	44.71	28348404
281	Ubiquitination	QRIHTGDKPYECKEC CEECCCCCCCCCCCC	51.33	-
286	Sumoylation	GDKPYECKECGKAFT CCCCCCCCCCCCCCC	44.06	-
286	Sumoylation	GDKPYECKECGKAFT CCCCCCCCCCCCCCC	44.06	-
390	Phosphorylation	TQHMRIHTGEKPYEC CCCCEEECCCCCCCC	44.67	28674419
416	Phosphorylation	TFIRHKRTHTGEKPF CCEECCCCCCCCCCC	28.70	-
418	Phosphorylation	IRHKRTHTGEKPFEC EECCCCCCCCCCCCC	46.56	21857030
421	Ubiquitination	KRTHTGEKPFECKEC CCCCCCCCCCCCCCC	57.25	-
426	Sumoylation	GEKPFECKECGKAFC CCCCCCCCCCCCEEE	49.17	-
426	Sumoylation	GEKPFECKECGKAFC CCCCCCCCCCCCEEE	49.17	-
446	Phosphorylation	IQHMRIHTGEKPYEC HHHCCCCCCCCCEEC	44.67	29496963
451	Phosphorylation	IHTGEKPYECSECGK CCCCCCCEECCCCCC	40.41	-
454	Phosphorylation	GEKPYECSECGKAFT CCCCEECCCCCCEEE	24.79	27251275
502	Phosphorylation	TRHMRIHTGEKPYVC CEEEEEECCCCCEEE	44.67	28111955
530	Phosphorylation	VRHNRIHTGEKPFEC HCCCCCCCCCCCCCC	44.67	28348404
556	Phosphorylation	ALTQHMRTHTGEKPF HHHHHHHHCCCCCCE	19.06	-
558	Phosphorylation	TQHMRTHTGEKPFEC HHHHHHCCCCCCEEC	46.56	-
561	Ubiquitination	MRTHTGEKPFECNEC HHHCCCCCCEECCCC	57.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN599_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN599_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN599_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN599_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.