ZN584_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN584_HUMAN
• UniProt AC: Q8IVC4
• Protein Name: Zinc finger protein 584
• Gene Name: ZNF584
• Organism: Homo sapiens (Human).
• Sequence Length: 421
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAGEAEAQLDPSLQGLVMFEDVTVYFSREEWGLLNVTQKGLYRDVMLENFALVSSLGLAPSRSPVFTQLEDDEQSWVPSWVDVTPVSRAEARRGFGLDGLCRVEDERAHPEHLKSYRVIQHQDTHSEGKPRRHTEHGAAFPPGSSCGQQQEVHVAEKLFKCSDCGKVFLKAFALLDHLITHSEERPFRCPTGRSAFKKSAHINPRKIHTGETAHVCNECGKAFSYPSKLRKHQKVHTGIKPFKCSDCGKTFNRKDALVLHQRIHTGERPYECSKCGKTFSVLSTLIRHRKVHIGERPYECTECGKFFKYNNSFILHQRVHTGERPFECKQCGKGYVTRSGLYQHWKVHTGERPYECSLCGKTFTTRSYRNRHQQFHTEERSYECTECGKAFKHSSTLLQHKKVHTPERRQEDRAHGKVVSC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	AEAQLDPSLQGLVMF HHHHCCHHHCCEEEE	32.75	24043423
23	Phosphorylation	LVMFEDVTVYFSREE EEEEEEEEEEEEHHH	23.08	24043423
25	Phosphorylation	MFEDVTVYFSREEWG EEEEEEEEEEHHHHC	6.10	24043423
27	Phosphorylation	EDVTVYFSREEWGLL EEEEEEEEHHHHCCC	22.54	24043423
37	Phosphorylation	EWGLLNVTQKGLYRD HHCCCCCCCCCCCCH	24.40	24425749
42	Phosphorylation	NVTQKGLYRDVMLEN CCCCCCCCCHHHHHH	17.28	24425749
54	Phosphorylation	LENFALVSSLGLAPS HHHHEEHHHCCCCCC	22.24	26270265
55	Phosphorylation	ENFALVSSLGLAPSR HHHEEHHHCCCCCCC	20.98	26270265
61	Phosphorylation	SSLGLAPSRSPVFTQ HHCCCCCCCCCCCCE	39.52	26270265
206	Sumoylation	SAHINPRKIHTGETA CCCCCCCCCCCCCHH	39.85	-
206	Sumoylation	SAHINPRKIHTGETA CCCCCCCCCCCCCHH	39.85	-
209	Phosphorylation	INPRKIHTGETAHVC CCCCCCCCCCHHHCC	39.94	25159151
308	Sumoylation	TECGKFFKYNNSFIL CCCCCEEEECCEEEE	50.64	-
308	Sumoylation	TECGKFFKYNNSFIL CCCCCEEEECCEEEE	50.64	-
312	Phosphorylation	KFFKYNNSFILHQRV CEEEECCEEEEEEEE	15.27	28555341
321	Phosphorylation	ILHQRVHTGERPFEC EEEEEEECCCCCEEC	37.57	21857030
339	Phosphorylation	GKGYVTRSGLYQHWK CCCEECCCCCCCCEE	24.63	28555341
349	Phosphorylation	YQHWKVHTGERPYEC CCCEEEECCCCCEEE	43.66	-
394	Phosphorylation	CGKAFKHSSTLLQHK HHHHCCCHHHHHHCC	26.13	28634298
395	Phosphorylation	GKAFKHSSTLLQHKK HHHCCCHHHHHHCCC	23.85	28634298
396	Phosphorylation	KAFKHSSTLLQHKKV HHCCCHHHHHHCCCC	34.21	28634298

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN584_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN584_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN584_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN584_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.