ZN577_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN577_HUMAN
• UniProt AC: Q9BSK1
• Protein Name: Zinc finger protein 577
• Gene Name: ZNF577
• Organism: Homo sapiens (Human).
• Sequence Length: 485
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MKNATIVMSVRREQGSSSGEGSLSFEDVAVGFTREEWQFLDQSQKVLYKEVMLENYINLVSIGYRGTKPDSLFKLEQGEPPGIAEGAAHSQICPGFVIQSRRYAGKDSDAFGGYGRSCLHIKRDKTLTGVKYHRCVKPSSPKSQLNDLQKICAGGKPHECSVCGRAFSRKAQLIQHQRTERGEKPHGCGECGKTFMRKIQLTEHQRTHTGEKPHECSECGKAFSRKSQLMVHQRTHTGEKPYRCSKCGKAFSRKCRLNRHQRSHTGEKLYGCSVCGKAFSQKAYLTAHQRLHTGDKPYKCSDCGRTFYFKSDLTRHQRIHTGEKPYECSECEKAFRSKSKLIQHQRTHTGERPYSCRECGKAFAHMSVLIKHEKTHIRETAINSLTVEKPSSRSHTSLYMSELIQEQKTVNTVPIEMPSSGTPPLLNKSERLVGRNVVIVEQPFPRNQAFVVNQEFEQRISLTNEVNVAPSVINYILYLTDIVSE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	DQSQKVLYKEVMLEN HHHHHHHHHHHHHHH	14.21	22817900
56	Phosphorylation	KEVMLENYINLVSIG HHHHHHHHEEEEEEE	5.04	18452278
61	Phosphorylation	ENYINLVSIGYRGTK HHHEEEEEEECCCCC	17.29	18452278
64	Phosphorylation	INLVSIGYRGTKPDS EEEEEEECCCCCCCC	12.28	22817900
71	Phosphorylation	YRGTKPDSLFKLEQG CCCCCCCCCEECCCC	44.21	24719451
103	Phosphorylation	FVIQSRRYAGKDSDA CEEECCCCCCCCCCC	20.70	26330541
108	Phosphorylation	RRYAGKDSDAFGGYG CCCCCCCCCCCCCCC	34.03	26330541
114	Phosphorylation	DSDAFGGYGRSCLHI CCCCCCCCCCCCEEE	15.11	26330541
152	S-nitrosylation	LNDLQKICAGGKPHE HHHHHHHHCCCCCCC	3.57	19483679
152	S-nitrosocysteine	LNDLQKICAGGKPHE HHHHHHHHCCCCCCC	3.57	-
207	Phosphorylation	QLTEHQRTHTGEKPH CCCCCCCCCCCCCCC	19.74	-
209	Phosphorylation	TEHQRTHTGEKPHEC CCCCCCCCCCCCCCC	46.56	-
221	Ubiquitination	HECSECGKAFSRKSQ CCCCHHHHCCCCHHC	58.90	-
235	Phosphorylation	QLMVHQRTHTGEKPY CEEEECCCCCCCCCC	19.74	-
237	Phosphorylation	MVHQRTHTGEKPYRC EEECCCCCCCCCCCC	46.56	24719451
240	Acetylation	QRTHTGEKPYRCSKC CCCCCCCCCCCCCCC	49.01	30593815
293	Phosphorylation	TAHQRLHTGDKPYKC HHHHHHCCCCCCEEC	52.23	24719451
321	Phosphorylation	TRHQRIHTGEKPYEC CCCCCEECCCCCCCC	44.67	28111955
384	Phosphorylation	IRETAINSLTVEKPS HHHHHHHEEEECCCC	21.21	29083192
386	Phosphorylation	ETAINSLTVEKPSSR HHHHHEEEECCCCCC	26.83	29083192
391	Phosphorylation	SLTVEKPSSRSHTSL EEEECCCCCCCCCHH	49.83	29083192
392	Phosphorylation	LTVEKPSSRSHTSLY EEECCCCCCCCCHHH	46.45	29083192
412	Phosphorylation	QEQKTVNTVPIEMPS HHCCCCCCEECCCCC	24.27	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN577_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN577_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN577_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN577_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.