ZN574_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN574_MOUSE
• UniProt AC: Q8BY46
• Protein Name: Zinc finger protein 574
• Gene Name: Znf574
• Organism: Mus musculus (Mouse).
• Sequence Length: 900
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MTEESEETVLYIEHRYVCSECNQLYGSLEEVLVHQNSHVPQQHFELVGVADPGVTVATEAASGTGLYQTLIQESQYQCLECGQLLLSPSQLLEHQELHLKMMAPQEAVPAKPPPKVPPLGSSAIHYECVDCKALFASQEMWLSHRQTHLRATPNKAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGAAVPSVAATTEMVTEVELLLYKCSECSQLFQMPADFLEHQATHFPAPVPEAAEPATQQETQVPSPTEAAVSQPEPLPASDHSYELRNELRNGEAIGRDRRGRKPRRNNSGESGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCPCGKTFVNLTKFLYHRRTHGAGGVPLPTTPVPPEEPAISFPEPAPAETGELEAPELPVCEESSAEPAAPGSYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVIHAGRQPYRCSSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRASRATRTPVAPSPTALSGTTSAAPAAPARRRGPECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEADGVQISG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
152	Phosphorylation	RQTHLRATPNKAPAP CHHHHCCCCCCCCCC	22.44	25293948
164	Phosphorylation	PAPVVLGSPVVLGPP CCCEECCCCEEECCC	15.45	30352176
301	Phosphorylation	RKPRRNNSGESGGAA CCCCCCCCCCCCCHH	47.70	26745281
304	Phosphorylation	RRNNSGESGGAATQE CCCCCCCCCCHHHHH	46.16	26745281
309	Phosphorylation	GESGGAATQELFCSA CCCCCHHHHHHHHHH	23.26	26745281
390	Phosphorylation	LAHRRAHTPNPLHSC HHHHHCCCCCCCCCC	24.63	-
411	Phosphorylation	VNLTKFLYHRRTHGA HHHHHHHHCCCCCCC	9.09	-
537	Phosphorylation	DCSKPFNSPANLARH CCCCCCCCHHHHHHH	26.26	-
721	Phosphorylation	TRTPVAPSPTALSGT CCCCCCCCCCCCCCC	25.74	25338131
728	Phosphorylation	SPTALSGTTSAAPAA CCCCCCCCCCCCCCC	17.75	-
793	Phosphorylation	KDHRRLHTGERPFAC CCCCCCCCCCCCCHH	45.38	-
836	Asymmetric dimethylarginine	PDCGKSYRSFSNLWK CCCCCCHHHHHHHHH	38.01	-
836	Methylation	PDCGKSYRSFSNLWK CCCCCCHHHHHHHHH	38.01	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN574_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN574_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN574_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN574_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.