ZN566_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN566_HUMAN
• UniProt AC: Q969W8
• Protein Name: Zinc finger protein 566
• Gene Name: ZNF566
• Organism: Homo sapiens (Human).
• Sequence Length: 418
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYLEQGKEPWLADRELTRGQWPVLESRCETKKLFLKKEIYEIESTQWEIMEKLTRRDFQCSSFRDDWECNRQFKKELGSQGGHFNQLVFTHEDLPTLSHHPSFTLQQIINSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYDPQLIQHQNLYW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
62	Ubiquitination	ISYLEQGKEPWLADR HHHHHCCCCCCCCCC	61.37	2189047
63	Ubiquitination	SYLEQGKEPWLADRE HHHHCCCCCCCCCCH	48.83	21890473
166	Phosphorylation	TLQQIINSKKKFCAS CHHHHHHCCCHHHCC	35.13	24260401
202	Sumoylation	IEKPYECKECGKSFR CCCCCCCCCCCCCCC	44.06	-
202	Sumoylation	IEKPYECKECGKSFR CCCCCCCCCCCCCCC	44.06	-
212	Phosphorylation	GKSFRHPSRLTHHQK CCCCCCHHHCCCCCC	33.52	26657352
222	Phosphorylation	THHQKIHTGKKPFEC CCCCCCCCCCCCCCC	54.92	26657352
230	Sumoylation	GKKPFECKECGKTFI CCCCCCCCCCCCEEE	49.17	-
230	Sumoylation	GKKPFECKECGKTFI CCCCCCCCCCCCEEE	49.17	-
234	Ubiquitination	FECKECGKTFICGSD CCCCCCCCEEEECCC	52.50	-
234	Sumoylation	FECKECGKTFICGSD CCCCCCCCEEEECCC	52.50	-
234	Sumoylation	FECKECGKTFICGSD CCCCCCCCEEEECCC	52.50	-
235 (in isoform 2)	Ubiquitination	-	11.97	-
250	Phosphorylation	TRHHRIHTGEKPYEC CCCCCCCCCCCCEEC	44.67	29496963
258	Sumoylation	GEKPYECKECGKAFS CCCCEECCCCCCCCC	44.06	-
258	Sumoylation	GEKPYECKECGKAFS CCCCEECCCCCCCCC	44.06	-
262	Ubiquitination	YECKECGKAFSSGSN EECCCCCCCCCCCCC	58.90	-
263 (in isoform 2)	Ubiquitination	-	8.54	-
278	Phosphorylation	TRHQRIHTGEKPYEC CCCCEEECCCCCCCC	44.67	29496963
286	Sumoylation	GEKPYECKECGKAFS CCCCCCCCCCCCCCC	44.06	-
286	Sumoylation	GEKPYECKECGKAFS CCCCCCCCCCCCCCC	44.06	-
290	Ubiquitination	YECKECGKAFSSGSN CCCCCCCCCCCCCCC	58.90	-
291 (in isoform 2)	Ubiquitination	-	8.54	-
306	Phosphorylation	TQHQRIHTGEKPYEC CCCCCCCCCCCCCCC	44.67	29496963
314	Sumoylation	GEKPYECKECGNAFS CCCCCCCCCCCCCCC	44.06	28112733
328	Sumoylation	SQSSQLIKHQRIHTG CCHHHHHHHCCCCCC	42.13	28112733
334	Phosphorylation	IKHQRIHTGEKPYEC HHHCCCCCCCCCCCC	44.67	29496963
343 (in isoform 2)	Ubiquitination	-	60.61	-
362	Phosphorylation	TRHQRIHTGEKPYEC CCCCEECCCCCCEEC	44.67	29496963
377	Phosphorylation	KICGKAYSQSSQLIS CCCCCCCCCCCHHHH	28.57	28555341
390	Phosphorylation	ISHHRIHTSEKPYEY HHCCCCCCCCCCCCH	35.89	21857030
397	Phosphorylation	TSEKPYEYRECGKNF CCCCCCCHHHCCCCC	13.08	-
417	Phosphorylation	LIQHQNLYW------ HHHCCCCCC------	19.34	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN566_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN566_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN566_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN566_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.