ZN552_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN552_HUMAN
• UniProt AC: Q9H707
• Protein Name: Zinc finger protein 552
• Gene Name: ZNF552
• Organism: Homo sapiens (Human).
• Sequence Length: 407
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVEDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLLRSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCMKHFSTKDILSQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKLFNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFTHSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQISSLRHHQRVHKRKGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
39	Phosphorylation	SEAQRCLYRDVTLEN HHHHHHHHCCCCHHH	14.37	22210691
43	Phosphorylation	RCLYRDVTLENLALM HHHHCCCCHHHHHHH	32.42	22210691
51	Phosphorylation	LENLALMSSLGCWCG HHHHHHHHHCCCCCC	24.22	22210691
80	Phosphorylation	QRETQVRTPMAGVSP EEECCCCCCCCCCCC	20.68	26853621
86	O-linked_Glycosylation	RTPMAGVSPKKAHPC CCCCCCCCCCCCCCC	30.04	30379171
86	Phosphorylation	RTPMAGVSPKKAHPC CCCCCCCCCCCCCCC	30.04	25159151
88	Sumoylation	PMAGVSPKKAHPCEM CCCCCCCCCCCCCCC	55.90	-
88	Sumoylation	PMAGVSPKKAHPCEM CCCCCCCCCCCCCCC	55.90	-
127	Sumoylation	RCEAWGNKLYDSGNF HHHHHHCCEECCCCC	44.48	-
127	Sumoylation	RCEAWGNKLYDSGNF HHHHHHCCEECCCCC	44.48	-
145	Ubiquitination	QNEHIGEKPYRGSVE CCCCCCCCCCCCCHH	41.98	-
150	Phosphorylation	GEKPYRGSVEEALFA CCCCCCCCHHHHHHH	19.84	22985185
158	Ubiquitination	VEEALFAKRCKLHVS HHHHHHHHHCEEEEC	51.50	-
161	Sumoylation	ALFAKRCKLHVSGES HHHHHHCEEEECCCC	45.73	-
161	Sumoylation	ALFAKRCKLHVSGES HHHHHHCEEEECCCC	45.73	-
165	Phosphorylation	KRCKLHVSGESSVFS HHCEEEECCCCHHCC	26.54	28555341
168	Phosphorylation	KLHVSGESSVFSESG EEEECCCCHHCCCCC	35.01	19053533
172	Phosphorylation	SGESSVFSESGKDFL CCCCHHCCCCCCHHH	28.79	19053533
176	Sumoylation	SVFSESGKDFLLRSG HHCCCCCCHHHHHCC	55.37	28112733
176	Acetylation	SVFSESGKDFLLRSG HHCCCCCCHHHHHCC	55.37	26051181
176	Sumoylation	SVFSESGKDFLLRSG HHCCCCCCHHHHHCC	55.37	-
194	Ubiquitination	QEATHTGKSNSKTEC EECCCCCCCCCCCEE	47.85	-
198	Sumoylation	HTGKSNSKTECVSLF CCCCCCCCCEEEEEE	53.22	-
198	Ubiquitination	HTGKSNSKTECVSLF CCCCCCCCCEEEEEE	53.22	-
198	Sumoylation	HTGKSNSKTECVSLF CCCCCCCCCEEEEEE	53.22	28112733
222	Phosphorylation	GGCMKHFSTKDILSQ CCHHHCCCHHHHHHH	33.98	22817900
223	Phosphorylation	GCMKHFSTKDILSQH CHHHCCCHHHHHHHH	31.62	22817900
224	Ubiquitination	CMKHFSTKDILSQHE HHHCCCHHHHHHHHH	41.39	-
228	Phosphorylation	FSTKDILSQHERLLP CCHHHHHHHHHHHCC	29.80	22817900
251	Sumoylation	ECGKSSSKYDSFSNH ECCCCCCCCCCCCCC	55.83	25218447
251	Ubiquitination	ECGKSSSKYDSFSNH ECCCCCCCCCCCCCC	55.83	-
251	Sumoylation	ECGKSSSKYDSFSNH ECCCCCCCCCCCCCC	55.83	-
254	Phosphorylation	KSSSKYDSFSNHQGV CCCCCCCCCCCCCCC	27.73	28555341
266	Sumoylation	QGVHTREKPYTCGIC CCCCCCCCCEECCCC	39.78	-
266	Sumoylation	QGVHTREKPYTCGIC CCCCCCCCCEECCCC	39.78	25218447
280	Sumoylation	CGKLFNSKSHLLVHQ CCCCCCCCCCEEEEE	42.89	-
280	Sumoylation	CGKLFNSKSHLLVHQ CCCCCCCCCCEEEEE	42.89	-
291	Phosphorylation	LVHQRIHTGEKPYEC EEEEEECCCCCCCCC	44.67	21712546
308	Sumoylation	CQKFFRHKYHLIAHQ HHHHHHHCCEEEEEC	30.06	-
308	Sumoylation	CQKFFRHKYHLIAHQ HHHHHHHCCEEEEEC	30.06	28112733
309	Phosphorylation	QKFFRHKYHLIAHQR HHHHHHCCEEEEECC	8.85	-
319	Phosphorylation	IAHQRVHTGERPYEC EEECCCCCCCCCEEC	37.57	28348404
327	Phosphorylation	GERPYECSDCGKSFT CCCCEECCCCCCCEE	24.81	28348404
347	Phosphorylation	RVHKRVHTGQKPYEC EEECEEECCCCCEEC	38.15	28674419
350	Sumoylation	KRVHTGQKPYECSEC CEEECCCCCEECCCC	51.41	-
350	Sumoylation	KRVHTGQKPYECSEC CEEECCCCCEECCCC	51.41	-
369	Ubiquitination	AESSSLTKHRRVHTG HHCCCCCCCCCCCCC	40.17	-
369	Sumoylation	AESSSLTKHRRVHTG HHCCCCCCCCCCCCC	40.17	-
369	Sumoylation	AESSSLTKHRRVHTG HHCCCCCCCCCCCCC	40.17	-
375	Phosphorylation	TKHRRVHTGEKPYGC CCCCCCCCCCCCCCC	44.15	28674419
393	Phosphorylation	EKKFRQISSLRHHQR HHHHHHHHHHHHHHH	18.25	24719451
394	Phosphorylation	KKFRQISSLRHHQRV HHHHHHHHHHHHHHH	30.93	25954137

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN552_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN552_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN552_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN552_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.