ZN529_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN529_HUMAN
• UniProt AC: Q6P280
• Protein Name: Zinc finger protein 529
• Gene Name: ZNF529
• Organism: Homo sapiens (Human).
• Sequence Length: 563
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MANSSFIGDHVHGAPHAVMPEVEFPDQFFTVLTMDHELVTLRDVVINFSQEEWEYLDSAQRNLYWDVMMENYSNLLSLDLESRNETKHLSVGKDIIQNTGSQWEVMESSKLCGLEGSIFRNDWQSKSKIDLQGPEVGYFSQMKIISENVPSYKTHESLTLPRRTHDSEKPYEYKEYEKVFSCDLEFDEYQKIHTGGKNYECNQCWKTFGIDNSSMLQLNIHTGVKPCKYMEYGNTCSFYKDFNVYQKIHNEKFYKCKEYRRTFERVGKVTPLQRVHDGEKHFECSFCGKSFRVHAQLTRHQKIHTDEKTYKCMECGKDFRFHSQLTEHQRIHTGEKPYKCMHCEKVFRISSQLIEHQRIHTGEKPYACKECGKAFGVCRELARHQRIHTGKKPYECKACGKVFRNSSSLTRHQRIHTGEKPYKCKECEKAFGVGSELTRHERIHSGQKPYECKECGKFFRLTSALIQHQRIHSGEKPYECKVCGKAFRHSSALTEHQRIHTGEKPYECKACGKAFRHSSSFTKHQRIHTDDKPYECKECGNSFSVVGHLTCQPKIYTGEKSFD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	TMDHELVTLRDVVIN ECCCCEEEHHHEEEE	32.36	30257219
87	Sumoylation	LESRNETKHLSVGKD CHHCCCCCCEEECHH	38.23	28112733
117	Phosphorylation	KLCGLEGSIFRNDWQ CCCCCCCCHHCCCCC	43.45	29083192
125	Phosphorylation	IFRNDWQSKSKIDLQ HHCCCCCCCCCEECC	5.33	29083192
126	Ubiquitination	FRNDWQSKSKIDLQG HCCCCCCCCCEECCC	43.95	-
153	Ubiquitination	SENVPSYKTHESLTL ECCCCCCCCCCCCCC	12.90	-
159	Phosphorylation	YKTHESLTLPRRTHD CCCCCCCCCCCCCCC	1.76	24719451
169	Ubiquitination	RRTHDSEKPYEYKEY CCCCCCCCCCCHHHE	28.27	-
191	Ubiquitination	LEFDEYQKIHTGGKN CCCCCCCEEECCCCC	7.04	-
197	Ubiquitination	QKIHTGGKNYECNQC CEEECCCCCCCCCCH	1.63	-
247	Ubiquitination	KDFNVYQKIHNEKFY CCCCHHHHHHCCCCH	60.15	-
262	Phosphorylation	KCKEYRRTFERVGKV HHHHHHHHHHHCCCC	11.83	30576142
268	Sumoylation	RTFERVGKVTPLQRV HHHHHCCCCCCCEEE	43.01	28112733
268	Ubiquitination	RTFERVGKVTPLQRV HHHHHCCCCCCCEEE	43.01	-
289	Ubiquitination	FECSFCGKSFRVHAQ EEEECCCCEEEEEEE	15.46	-
308	Sumoylation	QKIHTDEKTYKCMEC CCCCCCCCCEECCCC	3.37	-
308	Sumoylation	QKIHTDEKTYKCMEC CCCCCCCCCEECCCC	3.37	-
333	Phosphorylation	TEHQRIHTGEKPYKC CCCCCCCCCCCCCCC	35.38	29496963
350	Phosphorylation	CEKVFRISSQLIEHQ HHHEEEEHHHHHHCC	38.81	23927012
351	Phosphorylation	EKVFRISSQLIEHQR HHEEEEHHHHHHCCC	18.70	23927012
361	Phosphorylation	IEHQRIHTGEKPYAC HHCCCCCCCCCCCCH	42.72	28111955
406	Phosphorylation	CGKVFRNSSSLTRHQ CCCEEECCCCCCCCC	42.15	-
407	Phosphorylation	GKVFRNSSSLTRHQR CCEEECCCCCCCCCE	24.37	-
408	Phosphorylation	KVFRNSSSLTRHQRI CEEECCCCCCCCCEE	50.46	-
410	Phosphorylation	FRNSSSLTRHQRIHT EECCCCCCCCCEECC	2.49	-
417	Phosphorylation	TRHQRIHTGEKPYKC CCCCEECCCCCCCCC	40.78	29496963
453	Sumoylation	GQKPYECKECGKFFR CCCCEECCCCHHHHH	7.62	-
453	Sumoylation	GQKPYECKECGKFFR CCCCEECCCCHHHHH	7.62	-
457	Ubiquitination	YECKECGKFFRLTSA EECCCCHHHHHHHHH	17.04	-
478	Phosphorylation	IHSGEKPYECKVCGK CCCCCCCEEEEECCH	3.34	-
501	Phosphorylation	TEHQRIHTGEKPYEC CCCCCCCCCCCCCCC	39.43	29496963
518	Phosphorylation	CGKAFRHSSSFTKHQ CCCCCCCCCCCCCCC	9.08	28555341
520	Phosphorylation	KAFRHSSSFTKHQRI CCCCCCCCCCCCCCC	27.45	24719451
560	Ubiquitination	PKIYTGEKSFD---- CEEECCCCCCC----		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN529_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN529_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN529_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN529_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.