ZN528_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN528_HUMAN
• UniProt AC: Q3MIS6
• Protein Name: Zinc finger protein 528
• Gene Name: ZNF528
• Organism: Homo sapiens (Human).
• Sequence Length: 628
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MALTQGPLKFMDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLGICLPDLSVTSMLEQKRDPWTLQSEEKIANDPDGRECIKGVNTERSSKLGSNAGNKPCKNQLGFTFQLHLSDLQLFQAERKISGCKHFEKPVSDNSSVSPLEKISSSVKSHLLNKYRNNFDHAPLLPQEQKAHIREKAYKCNEHGQVFRASASLTNQVIHNADNPYKCSECGKVFSCSSKLVIHRRMHTGEKPYKCHECGKLFSSNSNLSQHQRIHTGEKPYKCHECDKVFRSSSKLAQHQRIHTGEKPYKCHECDKVFNQIAHLVRHQKIHTGEKPYSCNKCGKVFSRHSYLAEHQTVHTGEKPYKCEECGKAFSVRSSLITHQLIHTGRKPYKCKECDKVFGRKCFLTSHQRIHTRERPYGCSQCGKIFSQKSDLIRHRKTHTDEKPYKCNKCGTAFREFSDLTAHFLIHSGEKPYECKECGKVFRYKSSLTSHHRIHTGEKPYKCNRCGKVFSRSSNLVCHQKIHTGEKPYKCNQCGKVFNQASYLTRHQIIHTGERPYRCSKCGKAFRGCSGLTAHLAIHTEKKSHECKECGKIFTQKSSLTNHHRIHIGEKPYKCTLCSKVFSHNSDLAQHQRVHS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	MDVAIEFSQEEWKCL HEEEEEECHHHHHHC	24.72	27251275
23	Ubiquitination	EFSQEEWKCLDPAQR EECHHHHHHCCHHHH	28.35	-
146	Phosphorylation	VSDNSSVSPLEKISS CCCCCCCCCHHHHHH	26.22	24719451
153	Phosphorylation	SPLEKISSSVKSHLL CCHHHHHHHHHHHHH	42.49	-
157	Phosphorylation	KISSSVKSHLLNKYR HHHHHHHHHHHHHHH	19.74	-
264	Phosphorylation	SQHQRIHTGEKPYKC CHHCCHHCCCCCCCH	44.67	29496963
292	Phosphorylation	AQHQRIHTGEKPYKC HHCCCCCCCCCCCCH	44.67	29496963
320	Phosphorylation	VRHQKIHTGEKPYSC HHHCCCCCCCCCCCC	50.97	28555341
326	Phosphorylation	HTGEKPYSCNKCGKV CCCCCCCCCCCCCCE	21.53	22468782
348	Phosphorylation	AEHQTVHTGEKPYKC CCCCEEECCCCCEEC	42.58	29496963
351	Sumoylation	QTVHTGEKPYKCEEC CEEECCCCCEECCCC	55.80	-
351	Ubiquitination	QTVHTGEKPYKCEEC CEEECCCCCEECCCC	55.80	-
351	Sumoylation	QTVHTGEKPYKCEEC CEEECCCCCEECCCC	55.80	-
353	Phosphorylation	VHTGEKPYKCEECGK EECCCCCEECCCCCC	39.06	-
354	Sumoylation	HTGEKPYKCEECGKA ECCCCCEECCCCCCE	43.63	-
354	Ubiquitination	HTGEKPYKCEECGKA ECCCCCEECCCCCCE	43.63	-
354	Sumoylation	HTGEKPYKCEECGKA ECCCCCEECCCCCCE	43.63	-
409	Phosphorylation	IHTRERPYGCSQCGK CCCCCCCCCCHHCCH	36.66	-
468	Sumoylation	GEKPYECKECGKVFR CCCCEEECCCCCEEE	44.06	-
468	Sumoylation	GEKPYECKECGKVFR CCCCEEECCCCCEEE	44.06	-
488	Phosphorylation	TSHHRIHTGEKPYKC CCCCCCCCCCCCCCC	44.67	29496963
513	Ubiquitination	SNLVCHQKIHTGEKP CCEEEECEEECCCCC	16.88	-
516	Phosphorylation	VCHQKIHTGEKPYKC EEECEEECCCCCEEC	50.97	29496963
572	Phosphorylation	TAHLAIHTEKKSHEC HHHHHHHCCCCCCCH	43.30	-
603	Ubiquitination	HRIHIGEKPYKCTLC CEEECCCCCCCCCCC	48.73	-
618	Phosphorylation	SKVFSHNSDLAQHQR HHHHCCCHHHHHHHH	28.69	19664995

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN528_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN528_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN528_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN528_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.