ZN506_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN506_HUMAN
• UniProt AC: Q5JVG8
• Protein Name: Zinc finger protein 506
• Gene Name: ZNF506
• Organism: Homo sapiens (Human).
• Sequence Length: 444
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGPLQFRDVAIEFSLEEWHCLDAAQRNLYRDVMLENYRNLIFLGIVVSKPNLITCLEQGKKPLTMKRHEMIAKPPVMYSHFAQDLWSEQSIKDSFQKVILRRYEKCRHDNLQLKKGCESVDECPVHKRGYNGLKQCLATTQRKIFQCDEYVKFLHKFSNSNKHKIRDTGKKSFKCIEYGKTFNQSSTRTTYKKIDAGEKRYKCEECGKAYKQSSHLTTHKKIHTGEKPYKCEECGKAYKQSCNLTTHKIIHTGEKPYRCRECGKAFNHPATLFSHKKIHTGEKPYKCDKCGKAFISSSTLTKHEIIHTGEKPYKCEECGKAFNRSSNLTKHKRIHTGDVPYKCDECGKTFTWYSSLSKHKRAHTGEKPYKCEECGKAFTAFSTLTEHKIIHTGEKPYKCEECGKAFNWSSALNKHKKIHIRQKPCIVKNVENLLNVPQPLISIR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	RDVAIEFSLEEWHCL HHEEEEEECHHHHHH	23.29	-
48	Phosphorylation	IFLGIVVSKPNLITC EEEEEEECCCCHHHH	31.34	-
54	Phosphorylation	VSKPNLITCLEQGKK ECCCCHHHHHHCCCC	17.76	-
65	Ubiquitination	QGKKPLTMKRHEMIA CCCCCCCCCCHHHHC	4.78	21890473
97	Ubiquitination	SIKDSFQKVILRRYE HHHHHHHHHHHHHHH	29.27	21890473
195	Ubiquitination	RTTYKKIDAGEKRYK CCEEEEECCCCCEEE	58.35	22505724
221	Ubiquitination	SHLTTHKKIHTGEKP CCCCCCCCCCCCCCC	31.92	-
224	Phosphorylation	TTHKKIHTGEKPYKC CCCCCCCCCCCCEEC	50.97	29496963
227	Ubiquitination	KKIHTGEKPYKCEEC CCCCCCCCCEECHHH	55.80	22505724
229	Phosphorylation	IHTGEKPYKCEECGK CCCCCCCEECHHHHH	39.06	-
230	Sumoylation	HTGEKPYKCEECGKA CCCCCCEECHHHHHH	43.63	-
230	Sumoylation	HTGEKPYKCEECGKA CCCCCCEECHHHHHH	43.63	-
230	Ubiquitination	HTGEKPYKCEECGKA CCCCCCEECHHHHHH	43.63	-
245	Phosphorylation	YKQSCNLTTHKIIHT HHHHCCCCCCEEEEC	16.92	-
251	Ubiquitination	LTTHKIIHTGEKPYR CCCCEEEECCCCCEE	31.15	22505724
252	Phosphorylation	TTHKIIHTGEKPYRC CCCEEEECCCCCEEC	36.31	29496963
255	Ubiquitination	KIIHTGEKPYRCREC EEEECCCCCEECCCC	49.01	-
255	Sumoylation	KIIHTGEKPYRCREC EEEECCCCCEECCCC	49.01	-
255	Sumoylation	KIIHTGEKPYRCREC EEEECCCCCEECCCC	49.01	-
277	Ubiquitination	ATLFSHKKIHTGEKP CHHCCCCCCCCCCCC	34.01	-
279	Ubiquitination	LFSHKKIHTGEKPYK HCCCCCCCCCCCCCC	36.38	22505724
280	Phosphorylation	FSHKKIHTGEKPYKC CCCCCCCCCCCCCCC	50.97	29496963
283	Ubiquitination	KKIHTGEKPYKCDKC CCCCCCCCCCCCCCC	55.80	22505724
288	Ubiquitination	GEKPYKCDKCGKAFI CCCCCCCCCCCCEEE	45.16	22505724
298	Phosphorylation	GKAFISSSTLTKHEI CCEEECCCCCCCEEE	22.20	30631047
308	Phosphorylation	TKHEIIHTGEKPYKC CCEEEEECCCCCCCH	36.31	29496963
311	Ubiquitination	EIIHTGEKPYKCEEC EEEECCCCCCCHHHH	55.80	22505724
313	Phosphorylation	IHTGEKPYKCEECGK EECCCCCCCHHHHHH	39.06	-
314	Sumoylation	HTGEKPYKCEECGKA ECCCCCCCHHHHHHC	43.63	-
314	Acetylation	HTGEKPYKCEECGKA ECCCCCCCHHHHHHC	43.63	19825705
314	Sumoylation	HTGEKPYKCEECGKA ECCCCCCCHHHHHHC	43.63	-
314	Ubiquitination	HTGEKPYKCEECGKA ECCCCCCCHHHHHHC	43.63	-
320	Ubiquitination	YKCEECGKAFNRSSN CCHHHHHHCCCCCCC	62.56	22505724
341	Phosphorylation	IHTGDVPYKCDECGK CCCCCCCEECCCCCC	24.89	-
363	Ubiquitination	LSKHKRAHTGEKPYK CCCCCCCCCCCCCEE	38.14	22505724
370	Ubiquitination	HTGEKPYKCEECGKA CCCCCCEEHHHHHCE	43.63	-
370	Sumoylation	HTGEKPYKCEECGKA CCCCCCEEHHHHHCE	43.63	-
370	Sumoylation	HTGEKPYKCEECGKA CCCCCCEEHHHHHCE	43.63	-
388	Ubiquitination	FSTLTEHKIIHTGEK HHHHHCCCEEECCCC	36.80	-
392	Phosphorylation	TEHKIIHTGEKPYKC HCCCEEECCCCCEEC	36.31	29496963
395	Ubiquitination	KIIHTGEKPYKCEEC CEEECCCCCEECCHH	55.80	22505724
397	Phosphorylation	IHTGEKPYKCEECGK EECCCCCEECCHHCC	39.06	-
398	Sumoylation	HTGEKPYKCEECGKA ECCCCCEECCHHCCC	43.63	-
398	Acetylation	HTGEKPYKCEECGKA ECCCCCEECCHHCCC	43.63	19825711
398	Sumoylation	HTGEKPYKCEECGKA ECCCCCEECCHHCCC	43.63	-
398	Ubiquitination	HTGEKPYKCEECGKA ECCCCCEECCHHCCC	43.63	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN506_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN506_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN506_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN506_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.