ZN500_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN500_HUMAN
• UniProt AC: O60304
• Protein Name: Zinc finger protein 500
• Gene Name: ZNF500
• Organism: Homo sapiens (Human).
• Sequence Length: 480
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MATVPGLQPLPTLEQDLEQEEILIVKVEEDFCLEEEPSVETEDPSPETFRQLFRLFCYQEVAGPREALSRLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQARVREQQPESGEEAVVLVEGLQRKPRKHRQRGSELLSDDEVPLGIGGQFLKHQAEAQPEDLSLEEEARFSSQQPPAQLSHRPQRGPLLWPERGPPAPRHQEMASASPFLSAWSQVPVNLEDVAVYLSGEEPRCMDPAQRDAPLENEGPGIQLEDGGDGREDAPLRMEWYRVLSARCQGPGHPLPGQRPAPVRGLVRPDQPRGGPPPGRRASHGADKPYTCPECGKGFSKTSHLTKHQRTHTGERPYKCLVCGKGFSDRSNFSTHQRVHTGEKPYPCPECGKRFSQSSSLVIHRRTHSGERPYACTQCGKRFNNSSHFSAHRRTHTGEKPYTCPACGRGFRRGTDLHKHQRTHMGAGSLPTLQPVAPGGPGAKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
140	Phosphorylation	RKHRQRGSELLSDDE CCHHHCHHHHCCCCC	27.53	22199227
144	Phosphorylation	QRGSELLSDDEVPLG HCHHHHCCCCCCCCC	56.49	22199227
158	Ubiquitination	GIGGQFLKHQAEAQP CCCHHHHHHHHHHCC	34.65	-
318	Phosphorylation	PPPGRRASHGADKPY CCCCCCCCCCCCCCC	22.20	24719451
326	Phosphorylation	HGADKPYTCPECGKG CCCCCCCCCCCCCCC	30.06	28348404
336	Sumoylation	ECGKGFSKTSHLTKH CCCCCCCCCCCCCCC	52.35	-
336	Sumoylation	ECGKGFSKTSHLTKH CCCCCCCCCCCCCCC	52.35	-
376	Phosphorylation	STHQRVHTGEKPYPC CCCCCCCCCCCCCCC	44.15	29759185
381	Phosphorylation	VHTGEKPYPCPECGK CCCCCCCCCCCCCCC	28.65	29759185
391	Phosphorylation	PECGKRFSQSSSLVI CCCCCEECCCCCEEE	32.93	28555341
421	Phosphorylation	CGKRFNNSSHFSAHR CCCCCCCCCCCCCCC	26.71	22617229
422	Phosphorylation	GKRFNNSSHFSAHRR CCCCCCCCCCCCCCC	30.58	22617229
425	Phosphorylation	FNNSSHFSAHRRTHT CCCCCCCCCCCCCCC	20.10	-
430	Phosphorylation	HFSAHRRTHTGEKPY CCCCCCCCCCCCCCC	24.60	-
432	Phosphorylation	SAHRRTHTGEKPYTC CCCCCCCCCCCCCCC	46.56	21857030

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN500_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN500_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN500_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN500_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.