| UniProt ID | ZN486_HUMAN | |
|---|---|---|
| UniProt AC | Q96H40 | |
| Protein Name | Zinc finger protein 486 | |
| Gene Name | ZNF486 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 463 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | May be involved in transcriptional regulation.. | |
| Protein Sequence | MPGPLRSLEMESLQFRDVAVEFSLEEWHCLDTAQQNLYRDVMLENYRHLVFLGIIVSKPDLITCLEQGIKPLTMKRHEMIAKPPVVCSHFAQDLWPEQSIKDSYQKVILRKFEKCGHGNLHFKKGCESVDECKLHKRGYNGLNQCLTTTQSKIFQCGKYVKVFHQFSNSKRHKRRHTEKKPLKYIEGDKAFNQSSTHTTHKKIDTGEKPYKCEECGKAFNRSSHLTTHKITHTREKPYKCEECGKVFKYFSSFTTHKKIHSGEKPYICEECGKAFMYPYTLTTHKIIHTGEQPYKCKECDKAFNHPATLSSHKKIHTGEKPYTCDKCGKAFISSSILSKHEKIHTGEKPYKCEECGKAFTRSSHLTMHKIIHTGEKPYKCEECGKAFTWSAGLHKHRRTHTGEKPYKCEECGKAYTTSSNLTEHKTTHTGEKPYKCKECGKAFNWSSDLNKHKRIHIGQKPRT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 139 | Phosphorylation | CKLHKRGYNGLNQCL HCCHHCCCCHHHHHC | 15.30 | 23403867 | |
| 148 | Phosphorylation | GLNQCLTTTQSKIFQ HHHHHCCCCHHHHHH | 15.19 | - | |
| 149 | Phosphorylation | LNQCLTTTQSKIFQC HHHHCCCCHHHHHHC | 26.13 | - | |
| 194 | Phosphorylation | GDKAFNQSSTHTTHK CCCCCCCCCCCCCCC | 38.00 | 29083192 | |
| 195 | Phosphorylation | DKAFNQSSTHTTHKK CCCCCCCCCCCCCCC | 17.91 | 29083192 | |
| 196 | Phosphorylation | KAFNQSSTHTTHKKI CCCCCCCCCCCCCCC | 28.61 | 29083192 | |
| 198 | Phosphorylation | FNQSSTHTTHKKIDT CCCCCCCCCCCCCCC | 30.59 | 29083192 | |
| 199 | Phosphorylation | NQSSTHTTHKKIDTG CCCCCCCCCCCCCCC | 24.88 | 29083192 | |
| 211 | Sumoylation | DTGEKPYKCEECGKA CCCCCCEEHHHHHHC | 43.63 | - | |
| 211 | Ubiquitination | DTGEKPYKCEECGKA CCCCCCEEHHHHHHC | 43.63 | - | |
| 211 | Sumoylation | DTGEKPYKCEECGKA CCCCCCEEHHHHHHC | 43.63 | - | |
| 217 | Ubiquitination | YKCEECGKAFNRSSH EEHHHHHHCCCCCCC | 62.56 | - | |
| 239 | Sumoylation | HTREKPYKCEECGKV CCCCCCEECHHHHHH | 43.63 | - | |
| 239 | Ubiquitination | HTREKPYKCEECGKV CCCCCCEECHHHHHH | 43.63 | - | |
| 239 | Sumoylation | HTREKPYKCEECGKV CCCCCCEECHHHHHH | 43.63 | - | |
| 252 | Phosphorylation | KVFKYFSSFTTHKKI HHHHHHHCCCCCCCC | 19.40 | - | |
| 255 | Phosphorylation | KYFSSFTTHKKIHSG HHHHCCCCCCCCCCC | 29.68 | - | |
| 261 | Phosphorylation | TTHKKIHSGEKPYIC CCCCCCCCCCCCEEE | 52.71 | - | |
| 289 | Phosphorylation | TTHKIIHTGEQPYKC EECEEEECCCCCCCC | 31.82 | - | |
| 317 | Phosphorylation | SSHKKIHTGEKPYTC HCCCCCCCCCCCCCC | 50.97 | - | |
| 335 | Phosphorylation | GKAFISSSILSKHEK CCEECCHHHHHHCCC | 22.28 | 24719451 | |
| 342 | Acetylation | SILSKHEKIHTGEKP HHHHHCCCCCCCCCC | 39.23 | 7374235 | |
| 342 | Ubiquitination | SILSKHEKIHTGEKP HHHHHCCCCCCCCCC | 39.23 | - | |
| 345 | Phosphorylation | SKHEKIHTGEKPYKC HHCCCCCCCCCCCCC | 50.97 | 29496963 | |
| 348 | Ubiquitination | EKIHTGEKPYKCEEC CCCCCCCCCCCCHHH | 55.80 | - | |
| 350 | Phosphorylation | IHTGEKPYKCEECGK CCCCCCCCCCHHHCC | 39.06 | - | |
| 351 | Sumoylation | HTGEKPYKCEECGKA CCCCCCCCCHHHCCC | 43.63 | - | |
| 351 | Sumoylation | HTGEKPYKCEECGKA CCCCCCCCCHHHCCC | 43.63 | - | |
| 351 | Ubiquitination | HTGEKPYKCEECGKA CCCCCCCCCHHHCCC | 43.63 | - | |
| 357 | Acetylation | YKCEECGKAFTRSSH CCCHHHCCCEECCCC | 52.57 | 7374243 | |
| 369 | Ubiquitination | SSHLTMHKIIHTGEK CCCCEEEEEEECCCC | 32.31 | - | |
| 373 | Phosphorylation | TMHKIIHTGEKPYKC EEEEEEECCCCCEEC | 36.31 | 29496963 | |
| 376 | Ubiquitination | KIIHTGEKPYKCEEC EEEECCCCCEECCCC | 55.80 | - | |
| 378 | Phosphorylation | IHTGEKPYKCEECGK EECCCCCEECCCCCC | 39.06 | - | |
| 379 | Sumoylation | HTGEKPYKCEECGKA ECCCCCEECCCCCCE | 43.63 | - | |
| 379 | Sumoylation | HTGEKPYKCEECGKA ECCCCCEECCCCCCE | 43.63 | - | |
| 379 | Acetylation | HTGEKPYKCEECGKA ECCCCCEECCCCCCE | 43.63 | 19825699 | |
| 379 | Ubiquitination | HTGEKPYKCEECGKA ECCCCCEECCCCCCE | 43.63 | - | |
| 399 | Phosphorylation | GLHKHRRTHTGEKPY CCCCCCCCCCCCCCE | 24.60 | 28348404 | |
| 401 | Phosphorylation | HKHRRTHTGEKPYKC CCCCCCCCCCCCEEC | 46.56 | 26270265 | |
| 404 | Ubiquitination | RRTHTGEKPYKCEEC CCCCCCCCCEECCCC | 55.80 | - | |
| 406 | Phosphorylation | THTGEKPYKCEECGK CCCCCCCEECCCCCC | 39.06 | - | |
| 407 | Ubiquitination | HTGEKPYKCEECGKA CCCCCCEECCCCCCE | 43.63 | - | |
| 407 | Sumoylation | HTGEKPYKCEECGKA CCCCCCEECCCCCCE | 43.63 | - | |
| 407 | Sumoylation | HTGEKPYKCEECGKA CCCCCCEECCCCCCE | 43.63 | - | |
| 415 | Phosphorylation | CEECGKAYTTSSNLT CCCCCCEEECCCCCC | 17.65 | - | |
| 427 | Phosphorylation | NLTEHKTTHTGEKPY CCCCCCCCCCCCCCE | 23.42 | 28348404 | |
| 429 | Phosphorylation | TEHKTTHTGEKPYKC CCCCCCCCCCCCEEC | 44.97 | 24719451 | |
| 432 | Ubiquitination | KTTHTGEKPYKCKEC CCCCCCCCCEECCCC | 55.80 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZN486_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZN486_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZN486_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ZN486_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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