ZN443_HUMAN - dbPTM
ZN443_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN443_HUMAN
UniProt AC Q9Y2A4
Protein Name Zinc finger protein 443
Gene Name ZNF443
Organism Homo sapiens (Human).
Sequence Length 671
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MASVALEDVAVNFTREEWALLGPCQKNLYKDVMQETIRNLDCVVMKWKDQNIEDQYRYPRKNLRCRMLERFVESKDGTQCGETSSQIQDSIVTKNTLPGVGPCESSMRGEKVMGHSSLNCYIRVGAGHKPHEYHECGEKPDTHKQRGKAFSYHNSFQTHERLHTGKKPYDCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKPYECKQCSKAFPFYSSYLRHERTHTGEKPYKCKQCSKAFPDSSSCLIHERTHTGEKPYTCKQCGKAFSVSGSLQRHETTHSAEKPYACQQCGKAFHHLGSFQRHMIRHTGNGPHKCKICGKGFDCPSSLQSHERTHTGEKPYECKQCGKALSHRSSFRSHMIMHTGDGPHKCKVCGKAFVYPSVFQRHERTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYKCKLGKACIDFCSFQNHKTTHTGEKPYECKECGKAFSRFRYLSRHKRTHTGEKPYECKTCRKAFGHYDNLKVHERIHSGEKPYECKECGKAFSWLTCFLRHERIHMREKSYECPQCGKAFTHSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKTHTGENPYECKECGKAFASLSSLHRHKKTH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
26UbiquitinationALLGPCQKNLYKDVM
HHHHHHHHHHHHHHH		56.4929967540
30UbiquitinationPCQKNLYKDVMQETI
HHHHHHHHHHHHHHH		47.19-
48UbiquitinationDCVVMKWKDQNIEDQ
CEEEEEECCCCHHHH		43.8729967540
75UbiquitinationLERFVESKDGTQCGE
HHHHHHCCCCCCCCC		46.8229967540
96PhosphorylationDSIVTKNTLPGVGPC
HHHCCCCCCCCCCCC		35.5722210691
105PhosphorylationPGVGPCESSMRGEKV
CCCCCCCCCCCCCEE		35.8322210691
106PhosphorylationGVGPCESSMRGEKVM
CCCCCCCCCCCCEEE		7.1022210691
116PhosphorylationGEKVMGHSSLNCYIR
CCEEECCCCCCEEEE		30.6929083192
117PhosphorylationEKVMGHSSLNCYIRV
CEEECCCCCCEEEEE		20.2329083192
121PhosphorylationGHSSLNCYIRVGAGH
CCCCCCEEEEECCCC		7.2429083192
133PhosphorylationAGHKPHEYHECGEKP
CCCCCCCCCCCCCCC		10.4122817900
176UbiquitinationYDCKECGKSFSSLGN
CCHHHHCCCHHHHHH		61.05-
177PhosphorylationDCKECGKSFSSLGNL
CHHHHCCCHHHHHHH		18.6826699800
179PhosphorylationKECGKSFSSLGNLQR
HHHCCCHHHHHHHHH		31.5726699800
180PhosphorylationECGKSFSSLGNLQRH
HHCCCHHHHHHHHHH		37.9826699800
218PhosphorylationLLHMHERTHTGEKPY
HHHHHHCCCCCCCCC		22.3229396449
220PhosphorylationHMHERTHTGEKPYEC
HHHHCCCCCCCCCCC		46.5629496963
223UbiquitinationERTHTGEKPYECKQC
HCCCCCCCCCCCCHH		55.00-
246PhosphorylationSYLRHERTHTGEKPY
HHHCCCCCCCCCCCC		22.3229396449
248PhosphorylationLRHERTHTGEKPYEC
HCCCCCCCCCCCCCC		46.5629496963
251UbiquitinationERTHTGEKPYECKQC
CCCCCCCCCCCCCCC		55.00-
265PhosphorylationCSKAFPFYSSYLRHE
CCCCCCCHHHHHCCC		9.2828270605
266PhosphorylationSKAFPFYSSYLRHER
CCCCCCHHHHHCCCC		16.9428270605
267PhosphorylationKAFPFYSSYLRHERT
CCCCCHHHHHCCCCC		19.4628270605
268PhosphorylationAFPFYSSYLRHERTH
CCCCHHHHHCCCCCC		11.2128270605
274PhosphorylationSYLRHERTHTGEKPY
HHHCCCCCCCCCCCC		22.3228348404
276PhosphorylationLRHERTHTGEKPYKC
HCCCCCCCCCCCCCC		46.5626270265
279UbiquitinationERTHTGEKPYKCKQC
CCCCCCCCCCCCCCC		55.80-
281PhosphorylationTHTGEKPYKCKQCSK
CCCCCCCCCCCCCHH		39.8329438985
295PhosphorylationKAFPDSSSCLIHERT
HHCCCCCCCEEEECC		19.52-
302PhosphorylationSCLIHERTHTGEKPY
CCEEEECCCCCCCCE		22.32-
304PhosphorylationLIHERTHTGEKPYTC
EEEECCCCCCCCEEC		46.56-
386PhosphorylationSLQSHERTHTGEKPY
HHCCCCCCCCCCCCC		22.3229396449
388PhosphorylationQSHERTHTGEKPYEC
CCCCCCCCCCCCCCH		46.5629496963
391UbiquitinationERTHTGEKPYECKQC
CCCCCCCCCCCHHHH		55.00-
396SumoylationGEKPYECKQCGKALS
CCCCCCHHHHCCHHH		36.36-
396SumoylationGEKPYECKQCGKALS
CCCCCCHHHHCCHHH		36.36-
407PhosphorylationKALSHRSSFRSHMIM
CHHHCHHHHHHCCEE		25.3317081983
470PhosphorylationSLRRHETTHTGEKPY
HHHCCCCCCCCCCCE		17.9228348404
472PhosphorylationRRHETTHTGEKPYKC
HCCCCCCCCCCCEEC		44.9724719451
475UbiquitinationETTHTGEKPYKCKLG
CCCCCCCCCEECCCC		55.80-
490PhosphorylationKACIDFCSFQNHKTT
CCEEECCCCCCCCCC		29.8429083192
497PhosphorylationSFQNHKTTHTGEKPY
CCCCCCCCCCCCCCE		23.4227251275
499PhosphorylationQNHKTTHTGEKPYEC
CCCCCCCCCCCCEEC		44.9729496963
502UbiquitinationKTTHTGEKPYECKEC
CCCCCCCCCEECCHH		55.00-
507UbiquitinationGEKPYECKECGKAFS
CCCCEECCHHHHHHH		44.06-
507SumoylationGEKPYECKECGKAFS
CCCCEECCHHHHHHH		44.06-
507SumoylationGEKPYECKECGKAFS
CCCCEECCHHHHHHH		44.06-
514PhosphorylationKECGKAFSRFRYLSR
CHHHHHHHHHHHHHH		35.0624719451
525PhosphorylationYLSRHKRTHTGEKPY
HHHHCCCCCCCCCCC		28.7029396449
527PhosphorylationSRHKRTHTGEKPYEC
HHCCCCCCCCCCCCC		46.5629496963
530UbiquitinationKRTHTGEKPYECKTC
CCCCCCCCCCCCCHH		55.00-
539MethylationYECKTCRKAFGHYDN
CCCCHHHHHHCCCCC		50.6523644510
539"N6,N6-dimethyllysine"YECKTCRKAFGHYDN
CCCCHHHHHHCCCCC		50.65-
563UbiquitinationGEKPYECKECGKAFS
CCCCEECCHHHHHHH		44.06-
563SumoylationGEKPYECKECGKAFS
CCCCEECCHHHHHHH		44.06-
563SumoylationGEKPYECKECGKAFS
CCCCEECCHHHHHHH		44.06-
619UbiquitinationGENPYECKECGKAFA
CCCCCCHHHHHHHHH		44.06-
619SumoylationGENPYECKECGKAFA
CCCCCCHHHHHHHHH		44.06-
619SumoylationGENPYECKECGKAFA
CCCCCCHHHHHHHHH		44.06-
627PhosphorylationECGKAFASLSSLHRH
HHHHHHHHHHHHHHH		23.48-
652UbiquitinationGENPYECKECGKAFA
CCCCCCHHHHHHHHH		44.06-
652SumoylationGENPYECKECGKAFA
CCCCCCHHHHHHHHH		44.06-
652SumoylationGENPYECKECGKAFA
CCCCCCHHHHHHHHH		44.06-
660PhosphorylationECGKAFASLSSLHRH
HHHHHHHHHHHHHHH		23.48-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN443_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN443_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN443_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN443_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN443_HUMAN

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Related Literatures of Post-Translational Modification

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