ZN432_HUMAN - dbPTM
ZN432_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN432_HUMAN
UniProt AC O94892
Protein Name Zinc finger protein 432
Gene Name ZNF432
Organism Homo sapiens (Human).
Sequence Length 652
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MINAQELLTLEDVTVEFTWEEWQLLGPFQKDLYRDVMLEIYSNLLSMGYQVSKPDALSKLERGEEPWTMEDERHSRICPENNEVDDHLQDHLENQRMLKSVEQYHEHNAFGNTASQTKSLCLFRENHDTFELYIKTLKSNLSLVNQNKSCEINNSTKFSGDGKSFLHGNYEELYSAAKFSVSTKANSTKSQVSKHQRTHEIEKNHVCSECGKAFVKKSQLTDHERVHTGEKPYGCTLCAKVFSRKSRLNEHQRIHKREKSFICSECGKVFTMKSRLIEHQRTHTGEKPYICNECGKGFPGKRNLIVHQRNHTGEKSYICSECGKGFTGKSMLIIHQRTHTGEKPYICSECGKGFTTKHYVIIHQRNHTGEKPYICNECGKGFTMKSRMIEHQRTHTGEKPYICSECGKGFPRKSNLIVHQRNHTVEKSYLCSECGKGFTVKSMLIIHQRTHTGEKPYTCSECGKGFPLKSRLIVHQRTHTGEKPYRCSECGKGFIVNSGLMLHQRTHTGEKPYICNECGKGFAFKSNLVVHQRTHTGEKPFMCSECGKGFTMKRYLIVHQQIHTEEKSCICSECGRGFAKETELALHKQVHTGEKPYGCNECGKGFTMKSRLIVHQRTHTGEKPFVCSECRKAFSSKRNLIVHQRTHNGNKP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
41Nitrated tyrosineRDVMLEIYSNLLSMG
HHHHHHHHHHHHHCC		5.11-
41NitrationRDVMLEIYSNLLSMG
HHHHHHHHHHHHHCC		5.1116777052
41NitrationRDVMLEIYSNLLSMG
HHHHHHHHHHHHHCC		5.1116777052
139PhosphorylationLYIKTLKSNLSLVNQ
HHHHHHHHHHHCCCC		46.2224670416
142PhosphorylationKTLKSNLSLVNQNKS
HHHHHHHHCCCCCCC		34.2224670416
164PhosphorylationKFSGDGKSFLHGNYE
CCCCCCCHHCCCCHH		38.27-
170PhosphorylationKSFLHGNYEELYSAA
CHHCCCCHHHHHHHE		18.51-
174PhosphorylationHGNYEELYSAAKFSV
CCCHHHHHHHEEEEE		10.2727642862
175PhosphorylationGNYEELYSAAKFSVS
CCHHHHHHHEEEEEE		34.08-
198PhosphorylationQVSKHQRTHEIEKNH
HHCHHHHHHHHHHHH		19.7929759185
208PhosphorylationIEKNHVCSECGKAFV
HHHHHEEHHHHHHHH		34.5329759185
221PhosphorylationFVKKSQLTDHERVHT
HHHHHHCCCCCCCCC		27.89-
228PhosphorylationTDHERVHTGEKPYGC
CCCCCCCCCCCCCCC		44.15-
240AcetylationYGCTLCAKVFSRKSR
CCCCHHHHHHCCCCC		42.707963311
245AcetylationCAKVFSRKSRLNEHQ
HHHHHCCCCCCCHHH		38.447963319
282PhosphorylationRLIEHQRTHTGEKPY
HHHHECCCCCCCCCE		19.74-
284PhosphorylationIEHQRTHTGEKPYIC
HHECCCCCCCCCEEE		46.56-
317PhosphorylationNHTGEKSYICSECGK
CCCCCCEEEECCCCC		19.60-
327PhosphorylationSECGKGFTGKSMLII
CCCCCCCCCCEEEEE		52.98-
338PhosphorylationMLIIHQRTHTGEKPY
EEEEEECCCCCCCCE		19.74-
340PhosphorylationIIHQRTHTGEKPYIC
EEEECCCCCCCCEEE		46.56-
343AcetylationQRTHTGEKPYICSEC
ECCCCCCCCEEECCC		44.457428695
345PhosphorylationTHTGEKPYICSECGK
CCCCCCCEEECCCCC		26.15-
383PhosphorylationNECGKGFTMKSRMIE
CCCCCCCEEHHHHHE		32.1523532336
394PhosphorylationRMIEHQRTHTGEKPY
HHHEECCCCCCCCCE		19.74-
396PhosphorylationIEHQRTHTGEKPYIC
HEECCCCCCCCCEEE		46.56-
401PhosphorylationTHTGEKPYICSECGK
CCCCCCCEEECCCCC		26.15-
450PhosphorylationMLIIHQRTHTGEKPY
EEEEEECCCCCCCCE		19.74-
452PhosphorylationIIHQRTHTGEKPYTC
EEEECCCCCCCCEEC		46.56-
455AcetylationQRTHTGEKPYTCSEC
ECCCCCCCCEECCCC		44.677428703
478PhosphorylationRLIVHQRTHTGEKPY
EEEEEECCCCCCCCE		19.74-
480PhosphorylationIVHQRTHTGEKPYRC
EEEECCCCCCCCEEC		46.5624719451
483AcetylationQRTHTGEKPYRCSEC
ECCCCCCCCEECCCC		49.0125953088
485PhosphorylationTHTGEKPYRCSECGK
CCCCCCCEECCCCCC		35.01-
506PhosphorylationGLMLHQRTHTGEKPY
CEEEEECCCCCCCCE		19.74-
508PhosphorylationMLHQRTHTGEKPYIC
EEEECCCCCCCCEEE		46.56-
534PhosphorylationNLVVHQRTHTGEKPF
CEEEEECCCCCCCCE		19.74-
536PhosphorylationVVHQRTHTGEKPFMC
EEEECCCCCCCCEEC		46.56-
551PhosphorylationSECGKGFTMKRYLIV
CCCCCCCEEEEEEEE		30.3723532336
592PhosphorylationALHKQVHTGEKPYGC
HHHCEECCCCCCCCC		48.45-
597PhosphorylationVHTGEKPYGCNECGK
ECCCCCCCCCCCCCC		45.43-
607PhosphorylationNECGKGFTMKSRLIV
CCCCCCCEEECEEEE		32.1523532336
618PhosphorylationRLIVHQRTHTGEKPF
EEEEEECCCCCCCCE		19.74-
620PhosphorylationIVHQRTHTGEKPFVC
EEEECCCCCCCCEEC		46.56-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN432_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN432_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN432_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN432_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN432_HUMAN

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Related Literatures of Post-Translational Modification
Nitration
ReferencePubMed
"Nitroproteins from a human pituitary adenoma tissue discovered with anitrotyrosine affinity column and tandem mass spectrometry.";
Zhan X., Desiderio D.M.;
Anal. Biochem. 354:279-289(2006).
Cited for: NITRATION [LARGE SCALE ANALYSIS] AT TYR-41, AND MASS SPECTROMETRY.

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