ZN383_HUMAN - dbPTM
ZN383_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN383_HUMAN
UniProt AC Q8NA42
Protein Name Zinc finger protein 383
Gene Name ZNF383
Organism Homo sapiens (Human).
Sequence Length 475
Subcellular Localization Nucleus . Cytoplasm . Shuttling between the nucleus and cytoplasm may occur under different stimulation and growth conditions.
Protein Description May function as a transcriptional repressor, suppressing transcriptional activities mediated by MAPK signaling pathways..
Protein Sequence MAEGSVMFSDVSIDFSQEEWDCLDPVQRDLYRDVMLENYGNLVSMGLYTPKPQVISLLEQGKEPWMVGRELTRGLCSDLESMCETKLLSLKKEVYEIELCQREIMGLTKHGLEYSSFGDVLEYRSHLAKQLGYPNGHFSQEIFTPEYMPTFIQQTFLTLHQIINNEDRPYECKKCGKAFSQNSQFIQHQRIHIGEKSYECKECGKFFSCGSHVTRHLKIHTGEKPFECKECGKAFSCSSYLSQHQRIHTGKKPYECKECGKAFSYCSNLIDHQRIHTGEKPYECKVCGKAFTKSSQLFQHARIHTGEKPYECKECGKAFTQSSKLVQHQRIHTGEKPYECKECGKAFSSGSALTNHQRIHTGEKPYDCKECGKAFTQSSQLRQHQRIHAGEKPFECLECGKAFTQNSQLFQHQRIHTDEKPYECNECGKAFNKCSNLTRHLRIHTGEKPYNCKECGKAFSSGSDLIRHQGIHTNK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
89PhosphorylationMCETKLLSLKKEVYE
HHHHHHHHHHHHHHH		48.8824719451
208PhosphorylationKECGKFFSCGSHVTR
CCCCCEEECCCHHHH		22.24-
211PhosphorylationGKFFSCGSHVTRHLK
CCEEECCCHHHHCEE		21.07-
214PhosphorylationFSCGSHVTRHLKIHT
EECCCHHHHCEEEEC		13.62-
221PhosphorylationTRHLKIHTGEKPFEC
HHCEEEECCCCCCCC		50.9728348404
229SumoylationGEKPFECKECGKAFS
CCCCCCCCCCCCEEE		49.17-
229SumoylationGEKPFECKECGKAFS
CCCCCCCCCCCCEEE		49.17-
254PhosphorylationIHTGKKPYECKECGK
CCCCCCCCCCCCCHH		42.72-
257SumoylationGKKPYECKECGKAFS
CCCCCCCCCCHHHHH		44.06-
257SumoylationGKKPYECKECGKAFS
CCCCCCCCCCHHHHH		44.06-
265PhosphorylationECGKAFSYCSNLIDH
CCHHHHHHHHHHCCC		8.08-
277PhosphorylationIDHQRIHTGEKPYEC
CCCCCCCCCCCCEEC		44.6729496963
305PhosphorylationFQHARIHTGEKPYEC
HHHCEECCCCCCCCC		44.6729496963
313SumoylationGEKPYECKECGKAFT
CCCCCCCCHHHHHHH		44.06-
313SumoylationGEKPYECKECGKAFT
CCCCCCCCHHHHHHH		44.06-
333PhosphorylationVQHQRIHTGEKPYEC
HCCCCCCCCCCCCCC		44.6729496963
341SumoylationGEKPYECKECGKAFS
CCCCCCCCCCCCCCC		44.06-
341SumoylationGEKPYECKECGKAFS
CCCCCCCCCCCCCCC		44.06-
361PhosphorylationTNHQRIHTGEKPYDC
CCCCCCCCCCCCCCH		44.6728111955
420UbiquitinationQRIHTDEKPYECNEC
CCCCCCCCCCCCCHH		56.56-
445PhosphorylationTRHLRIHTGEKPYNC
HHHEEEECCCCCCCC		44.6728111955
460PhosphorylationKECGKAFSSGSDLIR
CCCCCCCCCCHHHHH		38.3523532336
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN383_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN383_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN383_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN383_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN383_HUMAN

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Related Literatures of Post-Translational Modification

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