ZN236_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN236_HUMAN
• UniProt AC: Q9UL36
• Protein Name: Zinc finger protein 236
• Gene Name: ZNF236
• Organism: Homo sapiens (Human).
• Sequence Length: 1845
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGLCGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAAGEWQALTHVF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
87	Phosphorylation	NLTLHKCTHSGEDPT EEEEEECCCCCCCCC	24.71	-
89	Phosphorylation	TLHKCTHSGEDPTCP EEEECCCCCCCCCCC	26.23	-
94	Phosphorylation	THSGEDPTCPVCNKK CCCCCCCCCCCCCCC	41.59	-
220	Phosphorylation	TRHIRIHTGERPFKC CCEEEEECCCCCEEH	38.06	23186163
248	Phosphorylation	QTHMIKHTGEKPHAC HHEECCCCCCCCCEE	41.87	23532336
306	Ubiquitination	SLNTHISKMHMGGPQ CCCHHHHHCCCCCCC	32.02	-
419	Phosphorylation	NDSCHAKTSAPHAQN CCCCCCCCCCCCCCC	30.79	26074081
420	Phosphorylation	DSCHAKTSAPHAQNP CCCCCCCCCCCCCCC	38.81	26074081
430	Phosphorylation	HAQNPDVSSVSNEQT CCCCCCHHHCCCCCC	32.19	26074081
431	Phosphorylation	AQNPDVSSVSNEQTD CCCCCHHHCCCCCCC	29.43	26074081
433	Phosphorylation	NPDVSSVSNEQTDPT CCCHHHCCCCCCCCC	36.28	26074081
437	Phosphorylation	SSVSNEQTDPTDAEQ HHCCCCCCCCCHHHH	37.45	26074081
440	Phosphorylation	SNEQTDPTDAEQEKE CCCCCCCCHHHHHHH	51.13	30576142
450	Phosphorylation	EQEKEQESPEKLDKK HHHHHHCCHHHCCHH	37.75	26074081
533	Phosphorylation	TAHIKTHTGIKAFKC HHHHHHCCCCCEEEC	45.92	-
643	Phosphorylation	PKNQFFQSYFNNNFV CCCHHHHHHHCCCCC	26.91	-
644	Phosphorylation	KNQFFQSYFNNNFVN CCHHHHHHHCCCCCC	10.27	-
696	Phosphorylation	QCGRGFVSAGVLKAH CCCCCEECHHHHHHH	19.62	17322306
712	Phosphorylation	RTHTGLKSFKCLICN HHCCCCCCCEEEEEC	34.67	24719451
990	Phosphorylation	KQHVRSHTGEKPYKC HHHHHHCCCCCCCCC	48.56	24719451
995	Phosphorylation	SHTGEKPYKCKLCGR HCCCCCCCCCCCCCC	39.83	22817900
1031	Phosphorylation	SCSVCNASFTTNGSL EEEECCCEEECCCCC	14.77	26853621
1047	Phosphorylation	RHMATHMSMKPYKCP HCHHHCCCCCCCCCC	18.95	24719451
1102	Methylation	EEEEHSDRNASRKSR CHHHCCCCCCCCCCC	43.56	115389279
1131	Phosphorylation	AKIRPQESATVSEKV HHCCCCCCCCCCHHH	24.80	27732954
1133	Phosphorylation	IRPQESATVSEKVLV CCCCCCCCCCHHHHH	33.57	27732954
1150	Phosphorylation	AAEKDRISELRDKQA HHHHHHHHHHHHHHH	31.32	20068231
1170	Phosphorylation	PKHANCCTYCPKSFK CCCCCCCCCCCCCCC	30.29	-
1171	Phosphorylation	KHANCCTYCPKSFKK CCCCCCCCCCCCCCC	7.89	-
1175	Phosphorylation	CCTYCPKSFKKPSDL CCCCCCCCCCCHHHH	27.69	-
1190	Phosphorylation	VRHVRIHTGEKPYKC HEEEEEECCCCCEEC	44.67	29496963
1196	Ubiquitination	HTGEKPYKCDECGKS ECCCCCEECCCCCCE	43.68	-
1263	Phosphorylation	CELRFRTSGRRKTHM CEEEEEECCCCCEEE	26.50	-
1713	Phosphorylation	QTHQAGPSLSSQKPR HHHCCCCCCCCCCCC	39.71	-
1745	Phosphorylation	ERHSRIHTGERPFHC HHHCCCCCCCCCEEE	38.06	28555341
1782	Phosphorylation	ERPYKCAYCVMGFTQ CCCCCCEEEEHHCCC	8.61	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN236_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN236_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN236_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN236_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.