ZN234_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN234_HUMAN
• UniProt AC: Q14588
• Protein Name: Zinc finger protein 234
• Gene Name: ZNF234
• Organism: Homo sapiens (Human).
• Sequence Length: 700
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MTTFKEGLTFKDVAVVFTEEELGLLDPVQRNLYQDVMLENFRNLLSVGHHPFKHDVFLLEKEKKLDIMKTATQRKGKSADKIQSEVETVPEAGRHEELYWGQIWKQIASDLIKYEDSMISISRFPRQGDLSCQVRAGLYTTHTGQKFYQCDEYKKSFTDVFNFDLHQQLHSGEKSHTCDECGKSFCYISALHIHQRVHMGEKCYKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCEECGRAFIHASHLQEHQRIHTGEKPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIHQRVHTGEKPYKCEECGKCFIQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEVCGKAFRQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRSAHLQAHQKVHTGEKPYKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKIHAAGTFYENDENSKNIRELSEGGSSTR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Acetylation	---MTTFKEGLTFKD ---CCCCCCCCCCCC	49.10	23236377
18	Phosphorylation	KDVAVVFTEEELGLL CCEEEEEEHHHHCCC	30.77	-
33	Phosphorylation	DPVQRNLYQDVMLEN CHHHHHHHHHHHHHH	13.25	20860994
64	Sumoylation	FLLEKEKKLDIMKTA EEEEHHHHHHHHHHH	53.11	-
64	Sumoylation	FLLEKEKKLDIMKTA EEEEHHHHHHHHHHH	53.11	-
70	Phosphorylation	KKLDIMKTATQRKGK HHHHHHHHHHHHCCC	19.98	29759185
72	Phosphorylation	LDIMKTATQRKGKSA HHHHHHHHHHCCCCH	33.85	29759185
77	Ubiquitination	TATQRKGKSADKIQS HHHHHCCCCHHHHHH	45.57	-
78	Phosphorylation	ATQRKGKSADKIQSE HHHHCCCCHHHHHHH	50.82	-
81	Ubiquitination	RKGKSADKIQSEVET HCCCCHHHHHHHEEE	42.22	-
84	Phosphorylation	KSADKIQSEVETVPE CCHHHHHHHEEECCC	47.27	-
88	Phosphorylation	KIQSEVETVPEAGRH HHHHHEEECCCCCCC	46.68	-
114	Phosphorylation	IASDLIKYEDSMISI HHHHHHHHHHCEEEE	20.27	-
117	Phosphorylation	DLIKYEDSMISISRF HHHHHHHCEEEEECC	13.18	-
140	Phosphorylation	QVRAGLYTTHTGQKF EEECEEEECCCCCEE	19.69	23532336
141	Phosphorylation	VRAGLYTTHTGQKFY EECEEEECCCCCEEE	12.13	23532336
204	Phosphorylation	VHMGEKCYKCDVCGK HHCCCCEEECCCCCC	26.22	22817900
233	Sumoylation	HTVEKPFKCVECGKG ECCCCCEEEEECCCC	45.99	-
233	Sumoylation	HTVEKPFKCVECGKG ECCCCCEEEEECCCC	45.99	-
245	Phosphorylation	GKGFSRRSTLTVHCK CCCCCCCCEEEEEEE	27.02	-
246	Phosphorylation	KGFSRRSTLTVHCKL CCCCCCCEEEEEEEE	25.33	-
255	Phosphorylation	TVHCKLHSGEKPYNC EEEEEECCCCCCCCH	60.11	26074081
258	Acetylation	CKLHSGEKPYNCEEC EEECCCCCCCCHHHH	57.22	25953088
260	Phosphorylation	LHSGEKPYNCEECGR ECCCCCCCCHHHHHH	43.44	26074081
273	Phosphorylation	GRAFIHASHLQEHQR HHEEEEHHHHHHHCC	15.57	26074081
283	Phosphorylation	QEHQRIHTGEKPFKC HHHCCCCCCCCCCCC	44.67	18669648
311	Phosphorylation	NNHCMVHTGEKPYKC HCCCEEECCCCCEEC	35.31	29496963
314	Sumoylation	CMVHTGEKPYKCEDC CEEECCCCCEECCCC	55.80	-
314	Sumoylation	CMVHTGEKPYKCEDC CEEECCCCCEECCCC	55.80	-
314	Ubiquitination	CMVHTGEKPYKCEDC CEEECCCCCEECCCC	55.80	-
317	Sumoylation	HTGEKPYKCEDCGKC ECCCCCEECCCCCCE	39.41	-
317	Sumoylation	HTGEKPYKCEDCGKC ECCCCCEECCCCCCE	39.41	-
339	Phosphorylation	RIHQRVHTGEKPYKC EEECEEECCCCCEEC	44.15	29496963
342	Sumoylation	QRVHTGEKPYKCEEC CEEECCCCCEECCCC	55.80	-
342	Sumoylation	QRVHTGEKPYKCEEC CEEECCCCCEECCCC	55.80	-
342	Ubiquitination	QRVHTGEKPYKCEEC CEEECCCCCEECCCC	55.80	-
344	Phosphorylation	VHTGEKPYKCEECGK EECCCCCEECCCCCC	39.06	-
345	Sumoylation	HTGEKPYKCEECGKC ECCCCCEECCCCCCE	43.63	-
345	Sumoylation	HTGEKPYKCEECGKC ECCCCCEECCCCCCE	43.63	-
345	Ubiquitination	HTGEKPYKCEECGKC ECCCCCEECCCCCCE	43.63	-
367	Phosphorylation	QAHRRIHTGEKPYVC CCCCCCCCCCCCEEE	44.67	27732954
395	Phosphorylation	QAHQGVHTGEKPYKC ECCCCCCCCCCCEEE	44.63	29496963
398	Sumoylation	QGVHTGEKPYKCNEC CCCCCCCCCEEECCC	55.80	-
398	Ubiquitination	QGVHTGEKPYKCNEC CCCCCCCCCEEECCC	55.80	-
398	Sumoylation	QGVHTGEKPYKCNEC CCCCCCCCCEEECCC	55.80	-
401	Sumoylation	HTGEKPYKCNECGKS CCCCCCEEECCCCCE	38.83	-
401	Sumoylation	HTGEKPYKCNECGKS CCCCCCEEECCCCCE	38.83	-
423	Phosphorylation	QVHLVVHTGEKPYKC EEEEEEECCCCCEEE	35.11	29496963
426	Sumoylation	LVVHTGEKPYKCEVC EEEECCCCCEEEEEC	55.80	-
426	Sumoylation	LVVHTGEKPYKCEVC EEEECCCCCEEEEEC	55.80	-
426	Ubiquitination	LVVHTGEKPYKCEVC EEEECCCCCEEEEEC	55.80	-
428	Phosphorylation	VHTGEKPYKCEVCGK EECCCCCEEEEECCH	39.06	-
429	Sumoylation	HTGEKPYKCEVCGKA ECCCCCEEEEECCHH	32.23	-
429	Sumoylation	HTGEKPYKCEVCGKA ECCCCCEEEEECCHH	32.23	-
440	Phosphorylation	CGKAFRQSSYLKIHL CCHHHHHCCEEEEEE	19.39	28348404
441	Phosphorylation	GKAFRQSSYLKIHLK CHHHHHCCEEEEEEE	26.58	28348404
442	Phosphorylation	KAFRQSSYLKIHLKA HHHHHCCEEEEEEEE	19.77	28348404
457	Sumoylation	HSVQKPFKCEECGQG ECCCCCEECCCCCCC	49.62	-
457	Sumoylation	HSVQKPFKCEECGQG ECCCCCEECCCCCCC	49.62	-
479	Phosphorylation	QIHQLIHTGEKPYKC EEEEHHHCCCCCEEC	39.79	29496963
482	Ubiquitination	QLIHTGEKPYKCEEC EHHHCCCCCEECCCC	55.80	-
484	Phosphorylation	IHTGEKPYKCEECGK HHCCCCCEECCCCCC	39.06	-
485	Sumoylation	HTGEKPYKCEECGKG HCCCCCEECCCCCCC	43.63	-
485	Sumoylation	HTGEKPYKCEECGKG HCCCCCEECCCCCCC	43.63	-
485	Ubiquitination	HTGEKPYKCEECGKG HCCCCCEECCCCCCC	43.63	-
507	Phosphorylation	KIHCRIHTGEKPYNC EEEEEEECCCCCCCH	44.67	27282143
535	Phosphorylation	LTHQRVHSGEKPFKC HHCCCCCCCCCCEEC	45.87	20068231
538	Ubiquitination	QRVHSGEKPFKCEEC CCCCCCCCCEECHHH	60.32	-
541	Sumoylation	HSGEKPFKCEECGKS CCCCCCEECHHHCCC	49.62	-
541	Sumoylation	HSGEKPFKCEECGKS CCCCCCEECHHHCCC	49.62	-
550	Phosphorylation	EECGKSFSRSAHLQA HHHCCCCCHHHHHHH	32.20	17081983
563	Phosphorylation	QAHQKVHTGEKPYKC HHHCCCCCCCCCEEC	50.45	29496963
566	Sumoylation	QKVHTGEKPYKCGEC CCCCCCCCCEECCCC	55.80	-
566	Sumoylation	QKVHTGEKPYKCGEC CCCCCCCCCEECCCC	55.80	-
566	Ubiquitination	QKVHTGEKPYKCGEC CCCCCCCCCEECCCC	55.80	-
569	Sumoylation	HTGEKPYKCGECGKG CCCCCCEECCCCCCC	44.27	-
569	Sumoylation	HTGEKPYKCGECGKG CCCCCCEECCCCCCC	44.27	-
591	Phosphorylation	DMHQRVHTGEKPYTC CCCCCCCCCCCCCCC	44.15	-
619	Phosphorylation	QLHQSVHTGEKPYKC EEHHCHHCCCCCEEC	44.90	29496963
622	Sumoylation	QSVHTGEKPYKCDVC HCHHCCCCCEECCCC	55.80	-
622	Ubiquitination	QSVHTGEKPYKCDVC HCHHCCCCCEECCCC	55.80	-
622	Sumoylation	QSVHTGEKPYKCDVC HCHHCCCCCEECCCC	55.80	-
647	Phosphorylation	QYHRRVHTGEKPYKC CCCCCCCCCCCCEEC	44.15	29496963
650	Sumoylation	RRVHTGEKPYKCEIC CCCCCCCCCEECEEC	55.80	-
650	Ubiquitination	RRVHTGEKPYKCEIC CCCCCCCCCEECEEC	55.80	-
650	Sumoylation	RRVHTGEKPYKCEIC CCCCCCCCCEECEEC	55.80	-
678	Phosphorylation	HKIHAAGTFYENDEN CEEEECCCCCCCCCC	20.51	28060719
680	Phosphorylation	IHAAGTFYENDENSK EEECCCCCCCCCCCC	17.41	28060719

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN234_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN234_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN234_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN234_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.