ZN142_HUMAN - dbPTM
ZN142_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN142_HUMAN
UniProt AC P52746
Protein Name Zinc finger protein 142
Gene Name ZNF142
Organism Homo sapiens (Human).
Sequence Length 1687
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MTDPLLDSQPASSTGEMDGLCPELLLIPPPLSNRGILGPVQSPCPSRDPAPIPTEPGCLLVEATATEEGPGNMEIIVETVAGTLTPGAPGETPAPKLPPGEREPSQEAGTPLPGQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVPGDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQLSARPEGPGHEPGTVVDPSLDQALPEMSEEVNTGRQEGSEAPHGGDLGGSPSPAEVEEGSCTLHLEALGVELESVTEPPLEEVTETAPMEFRPLGLEGPDGLEGPELSSFEGIGTSDLSAEENPLLEKPVSEPSTNPPSLEEAPNNWVGTFKTTPPAETAPLPPLPESESLLKALRRQDKEQAEALVLEGRVQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRKNKGLPRPDSPIPLQPVLPGTQASEDTESGKPPPASQEAELLLPKDAPLELPREPEETEEPLATVSGSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNSSPTEALKKHRFEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVQLEDPSPPAPAAPHTGPEG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMTDPLLDSQPASSTG
CCCCCCCCCCCCCCC		37.7229759185
154PhosphorylationRLEGDVVSGTESLFK
HCCCCEECCCHHHHH		39.5928112733
156PhosphorylationEGDVVSGTESLFKTH
CCCEECCCHHHHHHC		18.2023186163
158PhosphorylationDVVSGTESLFKTHMC
CEECCCHHHHHHCCC		38.6624719451
201PhosphorylationPNCQKFFTSKSKLKT
CCHHHHHCCHHHHHH		38.0827251275
202PhosphorylationNCQKFFTSKSKLKTH
CHHHHHCCHHHHHHH		29.7627251275
204O-linked_GlycosylationQKFFTSKSKLKTHLL
HHHHCCHHHHHHHHH		42.8830379171
207UbiquitinationFTSKSKLKTHLLREL
HCCHHHHHHHHHHHH		37.3229967540
246PhosphorylationASMHEDISNFYSDTY
HHHCHHHHHHHCCCC		32.9622210691
273UbiquitinationQALKEHLKSHTAAAA
HHHHHHHHHCHHHHH		41.9429967540
276PhosphorylationKEHLKSHTAAAAAEP
HHHHHHCHHHHHCCC		25.6928555341
424PhosphorylationIRHMLLHTGEKPHKC
HHHHHHHCCCCCCCC		47.18-
469SumoylationCGYVTKWKHYLRVHM
CCCCCEEHHHHHHHH		24.75-
469SumoylationCGYVTKWKHYLRVHM
CCCCCEEHHHHHHHH		24.75-
485PhosphorylationKHAGDLRYQCNQCSY
HHCCCHHHHHHCCHH		25.39-
533PhosphorylationELQKHMASQHHPGTP
HHHHHHHHCCCCCCC		23.5924043423
539PhosphorylationASQHHPGTPAPLYPC
HHCCCCCCCCCCCCC		22.2624043423
544PhosphorylationPGTPAPLYPCHYCSY
CCCCCCCCCCCCCCC		11.6224043423
548PhosphorylationAPLYPCHYCSYQSRH
CCCCCCCCCCCHHHH		6.9824043423
550PhosphorylationLYPCHYCSYQSRHKQ
CCCCCCCCCHHHHHH		21.0224043423
551PhosphorylationYPCHYCSYQSRHKQA
CCCCCCCCHHHHHHH		13.6224043423
553PhosphorylationCHYCSYQSRHKQAVL
CCCCCCHHHHHHHHH		28.2824043423
594SumoylationTLLFHKRKAHGYVPG
EEEEECCCCCCCCCC		49.9225218447
594SumoylationTLLFHKRKAHGYVPG
EEEEECCCCCCCCCC		49.92-
785PhosphorylationNWVGTFKTTPPAETA
CCCCCCCCCCCHHCC		40.1028348404
786PhosphorylationWVGTFKTTPPAETAP
CCCCCCCCCCHHCCC		28.0621712546
791PhosphorylationKTTPPAETAPLPPLP
CCCCCHHCCCCCCCC		35.3621712546
802PhosphorylationPPLPESESLLKALRR
CCCCCCHHHHHHHHH		48.5624719451
805UbiquitinationPESESLLKALRRQDK
CCCHHHHHHHHHCCH		51.1429967540
874PhosphorylationLCPECGASFKQQRGL
CCCCCCCCHHHHCCC		20.4724719451
904PhosphorylationKGLPRPDSPIPLQPV
CCCCCCCCCCCCCCC		27.6727050516
915PhosphorylationLQPVLPGTQASEDTE
CCCCCCCCCCCCCCC		21.0129083192
918PhosphorylationVLPGTQASEDTESGK
CCCCCCCCCCCCCCC		26.6229083192
958PhosphorylationETEEPLATVSGSPVP
CCCCCCCEECCCCCC		23.9228348404
960PhosphorylationEEPLATVSGSPVPPA
CCCCCEECCCCCCCC		29.2428348404
962PhosphorylationPLATVSGSPVPPAGN
CCCEECCCCCCCCCC		18.4130576142
990PhosphorylationPVPPAGNSSPTEAPK
CCCCCCCCCCCCCCC		36.4623663014
991PhosphorylationVPPAGNSSPTEAPKK
CCCCCCCCCCCCCCH		39.5825159151
993PhosphorylationPAGNSSPTEAPKKHH
CCCCCCCCCCCCHHC		46.8823663014
1010PhosphorylationPVPPAGNSSPTEALK
CCCCCCCCCHHHHHH		36.4630576142
1011PhosphorylationVPPAGNSSPTEALKK
CCCCCCCCHHHHHHH		39.5827050516
1013PhosphorylationPAGNSSPTEALKKHR
CCCCCCHHHHHHHHH		35.5227050516
1039PhosphorylationPFLCSRLSSITSHVA
HHHHHHHHHHHHHHH		20.70-
1040PhosphorylationFLCSRLSSITSHVAE
HHHHHHHHHHHHHHC		34.1828555341
1042PhosphorylationCSRLSSITSHVAEGC
HHHHHHHHHHHHCCC		18.09-
1043PhosphorylationSRLSSITSHVAEGCR
HHHHHHHHHHHCCCC		17.81-
1050MethylationSHVAEGCRGGRGGGG
HHHHCCCCCCCCCCC		62.5554560817
1069PhosphorylationPQTQPDVSPLSNGDS
CCCCCCCCCCCCCCC		27.7428985074
1183PhosphorylationCGFTCKQSRCMQQHR
CCCCCCHHHHHHHHH		16.9730631047
1193SumoylationMQQHRRLKHEGVKPH
HHHHHHHHHCCCCCC		37.4928112733
1242UbiquitinationQTFGTNSKLRLHRLR
CCCCCCCCEEEEEEE		39.43-
1242SumoylationQTFGTNSKLRLHRLR
CCCCCCCCEEEEEEE		39.4328112733
1254PhosphorylationRLRVHDKTPTHFCPL
EEECCCCCCCCCCCC		39.2025627689
1256PhosphorylationRVHDKTPTHFCPLCD
ECCCCCCCCCCCCCC		32.5825627689
1319PhosphorylationPAQPAPGSPAETTEG
CCCCCCCCCCCCCCC		21.6323401153
1323PhosphorylationAPGSPAETTEGPLHC
CCCCCCCCCCCCCCC		32.0530243723
1324PhosphorylationPGSPAETTEGPLHCS
CCCCCCCCCCCCCCC		30.3730243723
1331PhosphorylationTEGPLHCSRCGLLCP
CCCCCCCCCCCEECC		21.6230243723
1339PhosphorylationRCGLLCPSPASLRGH
CCCEECCCHHHHCCC		31.9127134283
1453SumoylationHGGTRLYKCTDCAYS
CCCCEEEEECCCCCC		34.94-
1453SumoylationHGGTRLYKCTDCAYS
CCCCEEEEECCCCCC		34.94-
1455PhosphorylationGTRLYKCTDCAYSTK
CCEEEEECCCCCCCC		29.93-
1462UbiquitinationTDCAYSTKNRQKITW
CCCCCCCCCCCEEEE		44.1629967540
1466SumoylationYSTKNRQKITWHSRI
CCCCCCCEEEEECEE		38.58-
1466SumoylationYSTKNRQKITWHSRI
CCCCCCCEEEEECEE		38.58-
1475PhosphorylationTWHSRIHTGEKPYHC
EEECEEECCCCCEEE		44.6728111955
1507SumoylationRIHKEERKYLCPECG
ECCHHHHCCCCCCCC		45.94-
1507SumoylationRIHKEERKYLCPECG
ECCHHHHCCCCCCCC		45.94-
1531PhosphorylationKYHMTKHTGLKPYQC
HHEECCCCCCCCCCC		45.8528555341
1543PhosphorylationYQCPECEYCTNRADA
CCCCCCCHHCCHHHH		19.07-
1545PhosphorylationCPECEYCTNRADALR
CCCCCHHCCHHHHHH		27.17-
1557PhosphorylationALRVHQETRHREARA
HHHHCHHHHHHHHHH		25.79-
1591SumoylationLRKHSEAKPYVCNVC
HHHHCCCCCCHHHHH		32.6028112733
1638UbiquitinationKQKFQVVKHVRRHHP
HHHHHHHHHHHHHCC		37.2129967540
1674PhosphorylationDVQLEDPSPPAPAAP
ECCCCCCCCCCCCCC		56.7025159151
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN142_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN142_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN142_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN142_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN142_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1319, AND MASSSPECTROMETRY.

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