ZN135_HUMAN - dbPTM
ZN135_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN135_HUMAN
UniProt AC P52742
Protein Name Zinc finger protein 135
Gene Name ZNF135
Organism Homo sapiens (Human).
Sequence Length 658
Subcellular Localization Nucleus .
Protein Description Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in transcriptional regulation..
Protein Sequence MTPGVRVSTDPEQVTFEDVVVGFSQEEWGQLKPAQRTLYRDVMLDTFRLLVSVGHWLPKPNVISLLEQEAELWAVESRLPQGVYPDLETRPKVKLSVLKQGISEEISNSVILVERFLWDGLWYCRGEDTEGHWEWSCESLESLAVPVAFTPVKTPVLEQWQRNGFGENISLNPDLPHQPMTPERQSPHTWGTRGKREKPDLNVLQKTCVKEKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRTHTG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMTPGVRVSTDPEQVT
CCCCCEECCCHHHCC		19.2727174698
9PhosphorylationTPGVRVSTDPEQVTF
CCCCEECCCHHHCCC		53.3627174698
15PhosphorylationSTDPEQVTFEDVVVG
CCCHHHCCCEEEEEE		22.4727174698
24PhosphorylationEDVVVGFSQEEWGQL
EEEEEECCHHHHHCC		30.6527174698
96PhosphorylationTRPKVKLSVLKQGIS
CCCCEEHHHHHHCCC		21.49-
254PhosphorylationCLKGFRNSSALTKHQ
HHHHCCCCCHHHCCC		16.84-
255PhosphorylationLKGFRNSSALTKHQR
HHHCCCCCHHHCCCC		30.74-
258PhosphorylationFRNSSALTKHQRIHT
CCCCCHHHCCCCCCC		26.63-
265PhosphorylationTKHQRIHTGEKPYKC
HCCCCCCCCCCCCCC		44.6729496963
291PhosphorylationPLIQHQRTHTGEKPY
HHHHHCCCCCCCCCE		19.74-
293PhosphorylationIQHQRTHTGEKPYEC
HHHCCCCCCCCCEEC		46.56-
296UbiquitinationQRTHTGEKPYECSEC
CCCCCCCCCEECCCC		55.00-
306PhosphorylationECSECGKSFSFRSSF
ECCCCCCEEEECCCC		16.0624719451
308PhosphorylationSECGKSFSFRSSFSQ
CCCCCEEEECCCCCC		27.1724719451
319PhosphorylationSFSQHERTHTGEKPY
CCCCCCCCCCCCCCE		22.32-
321PhosphorylationSQHERTHTGEKPYEC
CCCCCCCCCCCCEEH		46.56-
324UbiquitinationERTHTGEKPYECSEC
CCCCCCCCCEEHHHH		55.00-
349PhosphorylationTQHLRIHTGEKPYQC
HHEEEEECCCCCEEC		44.6728111955
377PhosphorylationTKHQRIHTGEKPYEC
CCCCCCCCCCCCEEH		44.6728111955
403PhosphorylationPLIQHQRTHTGEKPY
HHHHCCCCCCCCCCC		19.74-
405PhosphorylationIQHQRTHTGEKPYEC
HHCCCCCCCCCCCCC		46.5621857030
433PhosphorylationTEHRRIHTGEKPYGC
CCCCCCCCCCCCCCC		44.6728111955
459PhosphorylationSLSQHERTHTGEKPY
CCCCCCCCCCCCCCC		22.32-
461PhosphorylationSQHERTHTGEKPYEC
CCCCCCCCCCCCCCH		46.56-
489PhosphorylationTQHQRIHTGEKPYEC
CCCCEECCCCCCCCC		44.6728111955
517PhosphorylationTKHQRIHTGEKPYEC
CCCCCCCCCCCCCCC		44.6728111955
545PhosphorylationIQHQRIHTGEKPYEC
HHHCCCCCCCCCCCC		44.6728111955
599PhosphorylationSLSQHERTHTGEKPY
CCCHHCCCCCCCCCE		22.32-
601PhosphorylationSQHERTHTGEKPYEC
CHHCCCCCCCCCEEC		46.56-
614PhosphorylationECHDCGKSFRQSTHL
ECCCCCHHHHHCCCC		15.7929978859
618PhosphorylationCGKSFRQSTHLTQHR
CCHHHHHCCCCCCCC		17.3429978859
619PhosphorylationGKSFRQSTHLTQHRR
CHHHHHCCCCCCCCC		16.7429978859
622PhosphorylationFRQSTHLTQHRRIHT
HHHCCCCCCCCCCCC		18.0929978859
629PhosphorylationTQHRRIHTGEKPYAC
CCCCCCCCCCCCEEC		44.6726425664
650PhosphorylationFTHSSSLTKHQRTHT
EECCCCCCCCCCCCC		28.55-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN135_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN135_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN135_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN135_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN135_HUMAN

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Related Literatures of Post-Translational Modification

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