ZMYM4_MOUSE - dbPTM
ZMYM4_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZMYM4_MOUSE
UniProt AC A2A791
Protein Name Zinc finger MYM-type protein 4
Gene Name Zmym4
Organism Mus musculus (Mouse).
Sequence Length 1549
Subcellular Localization
Protein Description Plays a role in the regulation of cell morphology and cytoskeletal organization..
Protein Sequence MAEREVETGPRKRFEQKSDAVFDEIVENCGVMDTEMSEDTDHNLTPTLASMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVSSDNEDEQDCSSKDNLVSSVHTDGSLEVERRAAHQESDNENEIQIQNQLKKDFPKQFDQVSVFKSIRKDFCLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKGLDSRLKSSFFDKAANQVEETLHTHLPQNPETNFRDSSYPFASKESIGSELGNSFASNIRIKEEPLDDEYDRAVAPQQGLLDRVKDEPDNAQEYSHGQQQKTQEGELKISAVFSVSGSPLAPQLTTGFQPSLASPGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPLTKKTCSSCSKDILNPKDVISAQFENSTTSKDFCSQSCLSTYELKKKPIVTINTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCHVLQIEGQSKKFCSSMCVTSYKQKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPTGMNSSVVPLSQGQVIVSIPTGSSASAGGGSTPAVSPTSINSSAAAGLQRLAAQSQHVGFARSVVKLRCQHCNRLFATKPELLDYKGKMFQFCGKNCCDEYKKINNVMAMCEYCKIEKIIKETVRFSGADKSFCSEGCKLLYKHDLGKRWGSHCKMCSYCLQTSPKLIQNNLGGKVEDFCCEECMSKYTVLFYQMAKCDGCKRQGKLSESLKWRGDIKHFCNLLCILMFCHQQTVCDPPLQNNAVASISMVQAASAGPPSLRKDSTPVIANVVSLASAPAAQPTANTNSVLQGAVPTVTAKIIGDASTQTDALKLPPSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTDTPSEPQVMVVPVPVPVFVPIPLHLYTQYTPVPFGIPVPMPVPMFIPSSMDNDEKATEGIEDIKEKLATHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNAVQDADSELKPFSKGETEQDLEADFPSESFDPLNKGQGIQARSRTRRRHRDGFPQPRRRGRKKSVVPVEPRSLIQGALQGCSVSGMTLKYMYGVNAWKNWVQWKNAKDEQGDLKCGGGELASASPCSDSLGSAQDHALSQESSEQGCKARSVKLKEDILSCTFSELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLRNVTEHLKLSFAHVMRRTRTLKYSTKMTYLRFFPPLQKPESEPDKVTIGKRKRNEDDEAPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRSDVFYLQPERSCVPNSPMWYSTFPIDPGTLDTMLTRILMVREVHEELAKAKSEDSDAELSD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAEREVETG
------CCCCCCCCC		35.54-
106PhosphorylationNLVSSVHTDGSLEVE
CEEEEEECCCCHHHH		39.64-
109PhosphorylationSSVHTDGSLEVERRA
EEEECCCCHHHHHHH		24.94-
121PhosphorylationRRAAHQESDNENEIQ
HHHHHCCCCCCCHHH		38.8827087446
145PhosphorylationPKQFDQVSVFKSIRK
CCCCCCHHHHHHHCC		19.0629514104
161PhosphorylationFCLVRENSKETFSGK
EEEEECCCCCCCCCC		27.4126643407
164PhosphorylationVRENSKETFSGKEKN
EECCCCCCCCCCHHC		27.1725266776
166PhosphorylationENSKETFSGKEKNRD
CCCCCCCCCCHHCCC		57.2726643407
196PhosphorylationGLDSRLKSSFFDKAA
CHHHHHHHHHHHHHH		36.6529176673
197PhosphorylationLDSRLKSSFFDKAAN
HHHHHHHHHHHHHHH		28.4829176673
234PhosphorylationYPFASKESIGSELGN
CCCCCHHHHCCCCCC		35.6728066266
237PhosphorylationASKESIGSELGNSFA
CCHHHHCCCCCCCHH		28.1628066266
242PhosphorylationIGSELGNSFASNIRI
HCCCCCCCHHHCCEE		22.0125266776
245PhosphorylationELGNSFASNIRIKEE
CCCCCHHHCCEEECC		30.6828066266
250SumoylationFASNIRIKEEPLDDE
HHHCCEEECCCCCCC		46.2928289178
298PhosphorylationQEGELKISAVFSVSG
CCCCEEEEEEEEECC		19.4526643407
302PhosphorylationLKISAVFSVSGSPLA
EEEEEEEEECCCCCC		14.5826643407
304PhosphorylationISAVFSVSGSPLAPQ
EEEEEEECCCCCCCC		32.1526643407
306PhosphorylationAVFSVSGSPLAPQLT
EEEEECCCCCCCCCC		14.8326643407
313PhosphorylationSPLAPQLTTGFQPSL
CCCCCCCCCCCCHHH		21.4526643407
314PhosphorylationPLAPQLTTGFQPSLA
CCCCCCCCCCCHHHC		44.5926643407
319PhosphorylationLTTGFQPSLASPGMN
CCCCCCHHHCCCCHH		26.2826643407
322PhosphorylationGFQPSLASPGMNKML
CCCHHHCCCCHHHCC		27.5526643407
331PhosphorylationGMNKMLPSVPATAVR
CHHHCCCCCCCEEEE		36.4525195567
477PhosphorylationACFSKFRSANNLTMN
HHHHHHHCCCCCCCC		38.1823567750
482PhosphorylationFRSANNLTMNCCENC
HHCCCCCCCCCCCCC		14.4123567750
494PhosphorylationENCGGYCYSGSGQCH
CCCCCEEECCCCCEE		13.9523567750
497PhosphorylationGGYCYSGSGQCHVLQ
CCEEECCCCCEEEEE		21.5423567750
509PhosphorylationVLQIEGQSKKFCSSM
EEEEECCCCEECCHH		48.9823567750
736MalonylationCEYCKIEKIIKETVR
HHHCCHHHHHHHHCC		53.8826073543
777PhosphorylationSHCKMCSYCLQTSPK
CCCHHHHHHHHCCHH		7.70-
781PhosphorylationMCSYCLQTSPKLIQN
HHHHHHHCCHHHHHC		33.76-
782PhosphorylationCSYCLQTSPKLIQNN
HHHHHHCCHHHHHCC		13.69-
828PhosphorylationRQGKLSESLKWRGDI
CCCCCCCCCCCCCHH		31.6923140645
1063PhosphorylationEDEEKEKTLSQGESQ
CCHHHHHHHCCCCCC		32.5025619855
1065PhosphorylationEEKEKTLSQGESQTS
HHHHHHHCCCCCCCC		41.1727566939
1069PhosphorylationKTLSQGESQTSEQEL
HHHCCCCCCCCCEEE		45.6525619855
1071PhosphorylationLSQGESQTSEQELFL
HCCCCCCCCCEEEEE		43.4427566939
1072PhosphorylationSQGESQTSEQELFLD
CCCCCCCCCEEEEEE		29.6427149854
1080PhosphorylationEQELFLDTKIFEKDQ
CEEEEEEEEEEECCC		28.3428066266
1089PhosphorylationIFEKDQGSTYSGDLE
EEECCCCCCCCCCCC		20.6626643407
1090PhosphorylationFEKDQGSTYSGDLES
EECCCCCCCCCCCCC		28.6526643407
1091PhosphorylationEKDQGSTYSGDLESE
ECCCCCCCCCCCCCC		16.6226643407
1092PhosphorylationKDQGSTYSGDLESEA
CCCCCCCCCCCCCCE		26.3921659605
1101PhosphorylationDLESEAVSTPHSWEE
CCCCCEECCCCCHHH		43.1821149613
1102PhosphorylationLESEAVSTPHSWEEE
CCCCEECCCCCHHHH		20.5821149613
1105PhosphorylationEAVSTPHSWEEELNH
CEECCCCCHHHHHHH		37.0721149613
1113PhosphorylationWEEELNHYALKSNAV
HHHHHHHHHHHCCCC		16.7426643407
1182PhosphorylationRRRGRKKSVVPVEPR
CCCCCCCCCCCCCCH		31.2329176673
1200PhosphorylationQGALQGCSVSGMTLK
HHHHCCCCCCCEEHH		26.58-
1202PhosphorylationALQGCSVSGMTLKYM
HHCCCCCCCEEHHHH		13.42-
1205PhosphorylationGCSVSGMTLKYMYGV
CCCCCCEEHHHHHHH		24.51-
1240PhosphorylationCGGGELASASPCSDS
CCCCHHCCCCCCCCC		41.7325777480
1242PhosphorylationGGELASASPCSDSLG
CCHHCCCCCCCCCCC		24.7621659605
1245PhosphorylationLASASPCSDSLGSAQ
HCCCCCCCCCCCCHH		33.3521659605
1247PhosphorylationSASPCSDSLGSAQDH
CCCCCCCCCCCHHHH		20.5225777480
1250PhosphorylationPCSDSLGSAQDHALS
CCCCCCCCHHHHHHC		28.2225777480
1257PhosphorylationSAQDHALSQESSEQG
CHHHHHHCHHHHHCC		32.4625777480
1260PhosphorylationDHALSQESSEQGCKA
HHHHCHHHHHCCCCH		31.3825777480
1261PhosphorylationHALSQESSEQGCKAR
HHHCHHHHHCCCCHH		32.9425777480
1439AcetylationKPESEPDKVTIGKRK
CCCCCCCCCEECCCC		52.5823236377
1482PhosphorylationEFYLSKCSESVKQRS
HHHHHHCCHHHHHCC		36.3220495213
1540PhosphorylationEELAKAKSEDSDAEL
HHHHHHHCCCCCCCC		52.0421082442
1543PhosphorylationAKAKSEDSDAELSD-
HHHHCCCCCCCCCC-		34.3725521595
1548PhosphorylationEDSDAELSD------
CCCCCCCCC------		32.5525521595
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZMYM4_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZMYM4_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZMYM4_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZMYM4_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZMYM4_MOUSE

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-121, AND MASSSPECTROMETRY.
"A differential phosphoproteomic analysis of retinoic acid-treated P19cells.";
Smith J.C., Duchesne M.A., Tozzi P., Ethier M., Figeys D.;
J. Proteome Res. 6:3174-3186(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1540; SER-1543 ANDSER-1548, AND MASS SPECTROMETRY.

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