ZMYM3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZMYM3_MOUSE
• UniProt AC: Q9JLM4
• Protein Name: Zinc finger MYM-type protein 3
• Gene Name: Zmym3
• Organism: Mus musculus (Mouse).
• Sequence Length: 1370
• Subcellular Localization: Nucleus .
• Protein Description: Plays a role in the regulation of cell morphology and cytoskeletal organization..
• Protein Sequence: MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTYSKKPLGRKTCTFCKKEIWNTKDSVVVQTGPGGSFHEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGGLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQHTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDENGNLGKTPVKRATPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKAEMKSKGSQTEEWKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLMLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGETSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	GWAPPGPSPSSGALD CCCCCCCCCCCCCCC	43.24	27180971
53	Phosphorylation	APPGPSPSSGALDLL CCCCCCCCCCCCCCC	45.82	26745281
54	Phosphorylation	PPGPSPSSGALDLLD CCCCCCCCCCCCCCC	31.31	27087446
62	Phosphorylation	GALDLLDTPSGLEKD CCCCCCCCCCCCCCC	21.23	29472430
172	Phosphorylation	LATRRRGSPGQEEEH CCCCCCCCCCCCCCC	24.85	26370283
180	Phosphorylation	PGQEEEHTQGQPQSP CCCCCCCCCCCCCCC	37.36	29550500
186	Phosphorylation	HTQGQPQSPNAPPSP CCCCCCCCCCCCCCC	27.14	27841257
192	Phosphorylation	QSPNAPPSPSVGETL CCCCCCCCCCHHCCC	28.84	27841257
194	Phosphorylation	PNAPPSPSVGETLGD CCCCCCCCHHCCCCC	47.28	29550500
198	Phosphorylation	PSPSVGETLGDGINS CCCCHHCCCCCCCCC	30.06	29550500
205	Phosphorylation	TLGDGINSSQSKPGV CCCCCCCCCCCCCCC	28.03	19854140
208	Phosphorylation	DGINSSQSKPGVCTP CCCCCCCCCCCCCCC	42.64	19854140
214	Phosphorylation	QSKPGVCTPTAHPSL CCCCCCCCCCCCCCC	22.67	29550500
216	Phosphorylation	KPGVCTPTAHPSLPG CCCCCCCCCCCCCCC	21.31	29550500
258	Phosphorylation	PKPEVVDSTESIPVS CCCCCCCCCCCCCCC	23.59	21149613
259	Phosphorylation	KPEVVDSTESIPVSD CCCCCCCCCCCCCCC	29.32	21149613
261	Phosphorylation	EVVDSTESIPVSDED CCCCCCCCCCCCCCC	32.08	21149613
265	Phosphorylation	STESIPVSDEDSDAM CCCCCCCCCCCCCCC	29.90	23684622
269	Phosphorylation	IPVSDEDSDAMVDDP CCCCCCCCCCCCCCC	25.81	23684622
293	Phosphorylation	PRRSPRMSLRSSMAQ CCCCCCCCHHHHHHH	23.16	29514104
297	Phosphorylation	PRMSLRSSMAQRAGR CCCCHHHHHHHHHCC	16.23	29514104
338	Phosphorylation	GLPQLFCSSSCLTTY CCCHHHHCCHHCCCC	20.25	25195567
797	Phosphorylation	ENNHTVRTPDENGNL ECCCCCCCCCCCCCC	30.65	-
815	Phosphorylation	PVKRATPSVPTPPPP CCCCCCCCCCCCCCC	36.05	28285833
818	Phosphorylation	RATPSVPTPPPPPPP CCCCCCCCCCCCCCC	46.39	30482847
827	Phosphorylation	PPPPPPATPRKNKAA CCCCCCCCCCCCCCC	29.42	29895711
921	Ubiquitination	VETIEELKVKIPSNP HHHHHHHCCCCCCCC	44.77	-
950	Phosphorylation	AEELDKASSDLCDLV HHHHHHHCHHHHHHH	30.08	25293948
951	Phosphorylation	EELDKASSDLCDLVS HHHHHHCHHHHHHHC	39.19	25293948
958	Phosphorylation	SDLCDLVSNQSAEGL HHHHHHHCCCCHHHH	36.13	29899451
961	Phosphorylation	CDLVSNQSAEGLLED HHHHCCCCHHHHHHC	32.32	29899451
1046	Phosphorylation	GQKRLMLSESCSRDS CHHHEEECCCCCCCC	17.31	29514104
1048	Phosphorylation	KRLMLSESCSRDSLS HHEEECCCCCCCCCC	17.64	29514104
1050	Phosphorylation	LMLSESCSRDSLSSQ EEECCCCCCCCCCCC	48.69	24719451
1080	Phosphorylation	KCWVQSKYANGETSK EEEEEEHHCCCCCCC	15.56	28576409
1085	Phosphorylation	SKYANGETSKGDELR EHHCCCCCCCCCCCC	36.82	28576409
1172	Phosphorylation	FVQELNKSLSTWQPT HHHHHHHCCCCCCCC	26.86	22942356
1188	Phosphorylation	LPNNTVFSRVEEEHL CCCCCCCCCCCHHHH	30.95	22942356
1204	Phosphorylation	ECKQLGVYSPFVLLN HHHHHCCCCHHHHHH	14.61	26026062
1205	Phosphorylation	CKQLGVYSPFVLLNT HHHHCCCCHHHHHHH	14.95	26026062
1270	Phosphorylation	RQRKGRDTGPGKRKR CCCCCCCCCCCCCCC	43.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZMYM3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZMYM3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZMYM3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GT2D1_HUMAN	GTF2IRD1	physical	26275350

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.