| UniProt ID | ZIC4_HUMAN | |
|---|---|---|
| UniProt AC | Q8N9L1 | |
| Protein Name | Zinc finger protein ZIC 4 | |
| Gene Name | ZIC4 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 334 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Binds to DNA.. | |
| Protein Sequence | MRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQLTAASSPSVFPGLHEEPPQASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSLCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGRSPPPSSGYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 147 | Phosphorylation | TPSLCSKTFSTMHEL CHHHCCCCHHHHHHH | 13.41 | 24114839 | |
| 156 | Phosphorylation | STMHELVTHVTVEHV HHHHHHHHEEEEECC | 24.21 | 24114839 | |
| 159 | Phosphorylation | HELVTHVTVEHVGGP HHHHHEEEEECCCCH | 16.75 | 24114839 | |
| 199 | Phosphorylation | VNHIRVHTGEKPFPC EEEEEEECCCCCCCC | 44.15 | - | |
| 213 | Acetylation | CPFPGCGKVFARSEN CCCCCCCCEEEECCC | 37.95 | - | |
| 227 | Phosphorylation | NLKIHKRTHTGEKPF CEEEECCCCCCCCCE | 28.70 | - | |
| 229 | Phosphorylation | KIHKRTHTGEKPFRC EEECCCCCCCCCEEC | 46.56 | 29496963 | |
| 232 | Ubiquitination | KRTHTGEKPFRCEFE CCCCCCCCCEECEEC | 51.29 | - | |
| 317 | Phosphorylation | SSDCGHKSQVASSAA CCCCCCHHHHHHHHH | 24.98 | 25002506 | |
| 321 | Phosphorylation | GHKSQVASSAAVAAR CCHHHHHHHHHHHHH | 22.96 | 25002506 | |
| 322 | Phosphorylation | HKSQVASSAAVAART CHHHHHHHHHHHHHH | 15.54 | 25002506 | |
| 329 | Phosphorylation | SAAVAARTADLSE-- HHHHHHHHCCCCC-- | 21.57 | 25002506 | |
| 333 | Phosphorylation | AARTADLSE------ HHHHCCCCC------ | 41.63 | 25002506 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZIC4_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZIC4_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZIC4_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ZIC4_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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