ZHX1_RAT - dbPTM
ZHX1_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZHX1_RAT
UniProt AC Q8R515
Protein Name Zinc fingers and homeoboxes protein 1
Gene Name Zhx1
Organism Rattus norvegicus (Rat).
Sequence Length 873
Subcellular Localization Nucleus . Colocalized in the nucleus with DNMT3B..
Protein Description Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins (By similarity)..
Protein Sequence MASRRKSTTPCMVLASEQDPDLELISDLEEGPPVLTPVENARAESVSSDEEVHESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENTEQGESIDVSSSGISISKTPIMKMMKNKVENKRITVHHNSAEGTSEEKENGVKASREENAENTSSSASESNTSTSTVNQVHPSPAGTVVTPTAVLPGLAQVITAVSAQQNSNLVPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGANTLPVTAPIALTVAGVPNQTNVQKSQVPAAQPAAETKPATAAVPSSPSVRPEAALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSATIIIDSSDETPEPPAAAASQPKQSWNPFPDFAPQKFKEKTAEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKNKTKALKDEKVEVDESNVGSSKEEPGENSPGDEAVAPKSAGTGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAEESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSSNSSSLNGLSSLRKRGRGRPKGRGRGRPRGRPRGGKRMNTWDRVPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNRSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MASRRKSTTPCMVL
-CCCCCCCCCCCEEE		35.3825575281
8PhosphorylationMASRRKSTTPCMVLA
CCCCCCCCCCCEEEE		37.4825575281
9PhosphorylationASRRKSTTPCMVLAS
CCCCCCCCCCEEEEC		22.9125575281
16PhosphorylationTPCMVLASEQDPDLE
CCCEEEECCCCCCCC		31.4625575281
26PhosphorylationDPDLELISDLEEGPP
CCCCCCCCCCCCCCC		49.0925575281
36PhosphorylationEEGPPVLTPVENARA
CCCCCCCCCCCCCCC		26.06-
45PhosphorylationVENARAESVSSDEEV
CCCCCCCCCCCCHHH		26.7228432305
47PhosphorylationNARAESVSSDEEVHE
CCCCCCCCCCHHHHH		41.1528432305
48PhosphorylationARAESVSSDEEVHES
CCCCCCCCCHHHHHH		47.0528432305
55PhosphorylationSDEEVHESVDSDNQQ
CCHHHHHHCCCCCCC		19.1525575281
58PhosphorylationEVHESVDSDNQQNKK
HHHHHCCCCCCCCCE		35.9828689409
197PhosphorylationKVENKRITVHHNSAE
CCCCCEEEEECCCCC		20.1625575281
202PhosphorylationRITVHHNSAEGTSEE
EEEEECCCCCCCCHH		24.2825575281
206PhosphorylationHHNSAEGTSEEKENG
ECCCCCCCCHHHHHC		25.1925575281
207PhosphorylationHNSAEGTSEEKENGV
CCCCCCCCHHHHHCC		55.4025575281
429PhosphorylationNQTNVQKSQVPAAQP
CCCCCCHHHCCCCCC		21.2223984901
440PhosphorylationAAQPAAETKPATAAV
CCCCCCCCCCCCCCC		37.2923984901
444PhosphorylationAAETKPATAAVPSSP
CCCCCCCCCCCCCCC		24.5523984901
449PhosphorylationPATAAVPSSPSVRPE
CCCCCCCCCCCCCCH		48.5623984901
450PhosphorylationATAAVPSSPSVRPEA
CCCCCCCCCCCCCHH		18.3523984901
452PhosphorylationAAVPSSPSVRPEAAL
CCCCCCCCCCCHHHC		32.4823984901
464PhosphorylationAALVNPDSFGIRAKK
HHCCCCCCCCCCCCC		26.9923984901
542PhosphorylationSATIIIDSSDETPEP
CCEEEEECCCCCCCC		29.3125575281
543PhosphorylationATIIIDSSDETPEPP
CEEEEECCCCCCCCC		35.4025575281
546PhosphorylationIIDSSDETPEPPAAA
EEECCCCCCCCCHHH		37.6325575281
635PhosphorylationEKVEVDESNVGSSKE
CCEECCHHHCCCCCC		32.1423984901
639PhosphorylationVDESNVGSSKEEPGE
CCHHHCCCCCCCCCC		33.6723298284
640PhosphorylationDESNVGSSKEEPGEN
CHHHCCCCCCCCCCC		37.8523984901
648PhosphorylationKEEPGENSPGDEAVA
CCCCCCCCCCCCCCC		26.4221738781
739PhosphorylationSSLNGLSSLRKRGRG
CCCCHHHHHHHCCCC		36.9221630457
774PhosphorylationNTWDRVPSLIKFKTG
CCHHCCCCEEECCCC		39.61-
867UbiquitinationPPRHVKRKLSKSDD-
CCHHHHHHHHCCCC-		51.93-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZHX1_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZHX1_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZHX1_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZHX1_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZHX1_RAT

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Related Literatures of Post-Translational Modification

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