dbPTM

ZG16_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZG16_HUMAN
UniProt AC	O60844
Protein Name	Zymogen granule membrane protein 16
Gene Name	ZG16
Organism	Homo sapiens (Human).
Sequence Length	167
Subcellular Localization	Secreted, extracellular space, extracellular matrix . Cytoplasmic vesicle lumen . Golgi apparatus lumen . Stored in zymogen granules..
Protein Description	May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN..
Protein Sequence	MLTVALLALLCASASGNAIQARSSSYSGEYGGGGGKRFSHSGNQLDGPITALRVRVNTYYIVGLQVRYGKVWSDYVGGRNGDLEEIFLHPGESVIQVSGKYKWYLKKLLFVTDKGRYLSFGKDSGTSFNAVPLHPNTVLRFISGRSGSLIDAIGLHWDVYPSSCSRC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	GNAIQARSSSYSGEY CCCHHHCCCCCCCCC	27.01	29759185
24	Phosphorylation	NAIQARSSSYSGEYG CCHHHCCCCCCCCCC	27.95	29759185
25	Phosphorylation	AIQARSSSYSGEYGG CHHHCCCCCCCCCCC	25.27	-
30	Phosphorylation	SSSYSGEYGGGGGKR CCCCCCCCCCCCCCC	21.81	-
39	Phosphorylation	GGGGKRFSHSGNQLD CCCCCCCCCCCCCCC	22.30	23312004
41	Phosphorylation	GGKRFSHSGNQLDGP CCCCCCCCCCCCCCC	37.94	23312004
50	Phosphorylation	NQLDGPITALRVRVN CCCCCCEEEEEEEEC	23.83	24719451
143	Phosphorylation	NTVLRFISGRSGSLI CCEEEEEECCCCCCC	25.99	24719451
146	Phosphorylation	LRFISGRSGSLIDAI EEEEECCCCCCCHHE	35.94	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZG16_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZG16_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZG16_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ZG16_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZG16_HUMAN

Related Literatures of Post-Translational Modification