ZFP28_HUMAN - dbPTM
ZFP28_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZFP28_HUMAN
UniProt AC Q8NHY6
Protein Name Zinc finger protein 28 homolog
Gene Name ZFP28
Organism Homo sapiens (Human).
Sequence Length 868
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation. May have a role in embryonic development..
Protein Sequence MRGAASASVREPTPLPGRGAPRTKPRAGRGPTVGTPATLALPARGRPRSRNGLASKGQRGAAPTGPGHRALPSRDTALPQERNKKLEAVGTGIEPKAMSQGLVTFGDVAVDFSQEEWEWLNPIQRNLYRKVMLENYRNLASLGLCVSKPDVISSLEQGKEPWTVKRKMTRAWCPDLKAVWKIKELPLKKDFCEGKLSQAVITERLTSYNLEYSLLGEHWDYDALFETQPGLVTIKNLAVDFRQQLHPAQKNFCKNGIWENNSDLGSAGHCVAKPDLVSLLEQEKEPWMVKRELTGSLFSGQRSVHETQELFPKQDSYAEGVTDRTSNTKLDCSSFRENWDSDYVFGRKLAVGQETQFRQEPITHNKTLSKERERTYNKSGRWFYLDDSEEKVHNRDSIKNFQKSSVVIKQTGIYAGKKLFKCNECKKTFTQSSSLTVHQRIHTGEKPYKCNECGKAFSDGSSFARHQRCHTGKKPYECIECGKAFIQNTSLIRHWRYYHTGEKPFDCIDCGKAFSDHIGLNQHRRIHTGEKPYKCDVCHKSFRYGSSLTVHQRIHTGEKPYECDVCRKAFSHHASLTQHQRVHSGEKPFKCKECGKAFRQNIHLASHLRIHTGEKPFECAECGKSFSISSQLATHQRIHTGEKPYECKVCSKAFTQKAHLAQHQKTHTGEKPYECKECGKAFSQTTHLIQHQRVHTGEKPYKCMECGKAFGDNSSCTQHQRLHTGQRPYECIECGKAFKTKSSLICHRRSHTGEKPYECSVCGKAFSHRQSLSVHQRIHSGKKPYECKECRKTFIQIGHLNQHKRVHTGERSYNYKKSRKVFRQTAHLAHHQRIHTGESSTCPSLPSTSNPVDLFPKFLWNPSSLPSP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
59MethylationGLASKGQRGAAPTGP
CCCCCCCCCCCCCCC		45.44115920349
64PhosphorylationGQRGAAPTGPGHRAL
CCCCCCCCCCCCCCC		51.81-
73PhosphorylationPGHRALPSRDTALPQ
CCCCCCCCCCCCCCH		43.57-
130UbiquitinationIQRNLYRKVMLENYR
HHHHHHHHHHHHHHH		20.59-
303PhosphorylationSLFSGQRSVHETQEL
CCCCCCCCHHHHHHH		21.6729083192
307PhosphorylationGQRSVHETQELFPKQ
CCCCHHHHHHHCCCC		16.6829083192
316PhosphorylationELFPKQDSYAEGVTD
HHCCCCCCCCCCCCC		24.6130631047
333PhosphorylationSNTKLDCSSFRENWD
CCCCCCHHHHHHCCC		31.9830631047
367PhosphorylationEPITHNKTLSKERER
CCCCCCCCCCHHHHH		41.4029457462
369PhosphorylationITHNKTLSKERERTY
CCCCCCCCHHHHHHC		37.3929457462
384PhosphorylationNKSGRWFYLDDSEEK
CCCCCEEEECCCCCC		11.4026852163
388PhosphorylationRWFYLDDSEEKVHNR
CEEEECCCCCCCCCH		47.5226852163
428PhosphorylationKCNECKKTFTQSSSL
ECCCCCCCEECCCCC		19.8729888752
430PhosphorylationNECKKTFTQSSSLTV
CCCCCCEECCCCCEE		32.5429888752
432PhosphorylationCKKTFTQSSSLTVHQ
CCCCEECCCCCEEEE		20.8829888752
433PhosphorylationKKTFTQSSSLTVHQR
CCCEECCCCCEEEEE		21.3929888752
434PhosphorylationKTFTQSSSLTVHQRI
CCEECCCCCEEEEEE		33.0529888752
436PhosphorylationFTQSSSLTVHQRIHT
EECCCCCEEEEEEEC		20.2129888752
443PhosphorylationTVHQRIHTGEKPYKC
EEEEEEECCCCCEEC		44.6729496963
448PhosphorylationIHTGEKPYKCNECGK
EECCCCCEECCCCCC		38.9618767875
449SumoylationHTGEKPYKCNECGKA
ECCCCCEECCCCCCC		38.83-
449SumoylationHTGEKPYKCNECGKA
ECCCCCEECCCCCCC		38.83-
473AcetylationHQRCHTGKKPYECIE
CCCCCCCCCCCEEEE		52.2919811943
474AcetylationQRCHTGKKPYECIEC
CCCCCCCCCCEEEEC		54.9319813467
490PhosphorylationKAFIQNTSLIRHWRY
CEEHHCHHHHCCCCE		29.3724719451
528PhosphorylationNQHRRIHTGEKPYKC
CCCCCCCCCCCCCCC		44.6729496963
556PhosphorylationTVHQRIHTGEKPYEC
EEEEEEECCCCCCCC		44.6728111955
584PhosphorylationTQHQRVHSGEKPFKC
CHHCCHHCCCCCCCC		45.8720068231
587UbiquitinationQRVHSGEKPFKCKEC
CCHHCCCCCCCCCHH		60.32-
640PhosphorylationATHQRIHTGEKPYEC
HHCCCCCCCCCCCCC		44.6729496963
666PhosphorylationHLAQHQKTHTGEKPY
HHHHHHCCCCCCCCC		20.3527251275
668PhosphorylationAQHQKTHTGEKPYEC
HHHHCCCCCCCCCCC		52.8729496963
671UbiquitinationQKTHTGEKPYECKEC
HCCCCCCCCCCCCHH		55.00-
676SumoylationGEKPYECKECGKAFS
CCCCCCCCHHHHHHH		44.06-
676SumoylationGEKPYECKECGKAFS
CCCCCCCCHHHHHHH		44.06-
676UbiquitinationGEKPYECKECGKAFS
CCCCCCCCHHHHHHH		44.0633845483
686PhosphorylationGKAFSQTTHLIQHQR
HHHHHHHHHHHHCCC		13.67-
696PhosphorylationIQHQRVHTGEKPYKC
HHCCCCCCCCCCEEE		44.1529496963
699SumoylationQRVHTGEKPYKCMEC
CCCCCCCCCEEEECC		55.80-
699SumoylationQRVHTGEKPYKCMEC
CCCCCCCCCEEEECC		55.80-
699UbiquitinationQRVHTGEKPYKCMEC
CCCCCCCCCEEEECC		55.8033845483
701PhosphorylationVHTGEKPYKCMECGK
CCCCCCCEEEECCCH		28.08-
740PhosphorylationECGKAFKTKSSLICH
ECCCCEECCCCEEEE		29.70-
742PhosphorylationGKAFKTKSSLICHRR
CCCEECCCCEEEECC		35.29-
792AcetylationYECKECRKTFIQIGH
CCCHHHHCCEEEECC		60.4930593513
867PhosphorylationWNPSSLPSP------
CCCCCCCCC------		48.8422617229
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZFP28_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZFP28_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZFP28_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KDM1A_HUMANKDM1Aphysical
23455924
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZFP28_HUMAN

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Related Literatures of Post-Translational Modification

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