ZFAT_HUMAN - dbPTM
ZFAT_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZFAT_HUMAN
UniProt AC Q9P243
Protein Name Zinc finger protein ZFAT
Gene Name ZFAT
Organism Homo sapiens (Human).
Sequence Length 1243
Subcellular Localization Nucleus. Cytoplasm, cytosol.
Protein Description May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity)..
Protein Sequence METRAAENTAIFMCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNSSKTGDEFLVMKRKRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQEALVFTSSINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDTQLEEGRKEPEAPGEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDTSSAEAHAAPEKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVLSAGDPDPSRCLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWETATEAPEEPSTQYLHITEAEEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGAETHDATALASVVAMAPGTVTVVKQVTEEEPSSNHTVMIQETVQQASVELAEQHHLVVSSDDVEGIETVTVYTQGGEASEFIVYVQEAMQPVEEQAVEQPAQEL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
21PhosphorylationCKCCNLFSPNQSELL
ECCCCCCCCCHHHHH		26.5525159151
53PhosphorylationIIPLRPLSTPEPPNS
EEECCCCCCCCCCCC		44.6024247654
153PhosphorylationEGEAGNESDLELEKK
CCCCCCHHHHHHHHH		52.0427690223
244PhosphorylationDLVPRRGYQEYAIQQ
CCCCCCCCHHHCCCC		9.07-
247PhosphorylationPRRGYQEYAIQQTPY
CCCCCHHHCCCCCCC		8.0924275569
254PhosphorylationYAIQQTPYEQPMKSS
HCCCCCCCCCCCCCC		30.50-
260PhosphorylationPYEQPMKSSRLGPTQ
CCCCCCCCCCCCCCE		17.9024275569
322PhosphorylationNVHLRKHTGEKFACD
CHHHHHCCCCCEECC		50.5023532336
364PhosphorylationRFCKKKYSDVKNLIK
HHHCHHHHHHHHHHH		44.82-
383UbiquitinationAHDPQDKKVKEALDE
CCCCCCHHHHHHHHH		67.82-
385UbiquitinationDPQDKKVKEALDELC
CCCCHHHHHHHHHHH		46.26-
604PhosphorylationFLLKNDTSSAEAHAA
EEECCCCCCCHHHCC		30.3428555341
605PhosphorylationLLKNDTSSAEAHAAP
EECCCCCCCHHHCCC		32.0228555341
622PhosphorylationPPDMQHRSSVQTQGE
CCCCCCCCCCCCHHH		32.5129978859
623PhosphorylationPDMQHRSSVQTQGEV
CCCCCCCCCCCHHHH		20.4330301811
626PhosphorylationQHRSSVQTQGEVITL
CCCCCCCCHHHHHHH		36.0630301811
640PhosphorylationLLLSKAQSAGSDQES
HHHHHHHHCCCCCCC		39.1828857561
643PhosphorylationSKAQSAGSDQESHGA
HHHHHCCCCCCCCCC		35.5228857561
647PhosphorylationSAGSDQESHGAQSPL
HCCCCCCCCCCCCCC		22.9128857561
652PhosphorylationQESHGAQSPLGEGQN
CCCCCCCCCCCCCCC		22.8930576142
794PhosphorylationRHVIQKHSNILLKCP
HHHHHHCCCEEEECC		32.3829214152
809PhosphorylationTDGCDYSTPDKYKLQ
CCCCCCCCCCHHHHH		29.31-
827UbiquitinationKVHTALDKRSYSCPV
EEEECCCCCCCCCCC		44.06-
837UbiquitinationYSCPVCEKSFSEDRL
CCCCCCCCCCCHHHH		52.23-
846UbiquitinationFSEDRLIKSHIKTNH
CCHHHHHHHHHHCCC		40.34-
851PhosphorylationLIKSHIKTNHPEVSM
HHHHHHHCCCCCCCH		37.85-
859PhosphorylationNHPEVSMSTISEVLG
CCCCCCHHHHHHHHC		18.32-
916PhosphorylationFKCSLCEYATRSKSN
CCCCHHHHHHCCHHH		16.57-
925UbiquitinationTRSKSNLKAHMNRHS
HCCHHHHHHHHHHCC		40.26-
954PhosphorylationKSKGTLKSHKLLHTA
CCCCCCCCCCEEECC		29.0322210691
960PhosphorylationKSHKLLHTADGKQFK
CCCCEEECCCCCEEE		26.8122210691
990PhosphorylationRHMEQHVSFKPFRCA
HHHHHHCCCCCEECC		25.9825159151
1022PhosphorylationRKHPNEEYANVGTGE
CCCCCHHHCCCCHHH		9.4119690332
1158PhosphorylationVVAMAPGTVTVVKQV
HHHCCCCEEEEEEEC		16.3722468782
1166PhosphorylationVTVVKQVTEEEPSSN
EEEEEECCCCCCCCC		34.8722468782
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZFAT_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZFAT_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZFAT_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZFAT_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZFAT_HUMAN

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Related Literatures of Post-Translational Modification

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