dbPTM

ZDH15_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZDH15_HUMAN
UniProt AC	Q96MV8
Protein Name	Palmitoyltransferase ZDHHC15
Gene Name	ZDHHC15
Organism	Homo sapiens (Human).
Sequence Length	337
Subcellular Localization	Golgi apparatus membrane Multi-pass membrane protein .
Protein Description	Catalyzes palmitoylation of Cys residues on target proteins. Catalyzes palmitoylation of GAP43 and DLG4/PSD95..
Protein Sequence	MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPSVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSGPEKNGFNLGFIKNIQQVFGDKKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEETWEDNEDDNQDYPEGSSSLAVETET

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
97	Phosphorylation	SYTDKERYENEERPE CCCCHHHHCCCCCHH	24.97	-
107	Acetylation	EERPEVQKQMLVDMA CCCHHHHHHHHHHHH	42.73	18523073
130	Phosphorylation	TGSGAVRFCDRCHLI CCCCCCCCCCCCCCC	4.00	27251275
130 (in isoform 2)	Phosphorylation	-	4.00	27251275
132	Phosphorylation	SGAVRFCDRCHLIKP CCCCCCCCCCCCCCC	54.23	27251275
132 (in isoform 2)	Phosphorylation	-	54.23	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZDH15_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZDH15_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZDH15_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ZDH15_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZDH15_HUMAN

Related Literatures of Post-Translational Modification