ZC4H2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZC4H2_MOUSE
• UniProt AC: Q68FG0
• Protein Name: Zinc finger C4H2 domain-containing protein
• Gene Name: Zc4h2
• Organism: Mus musculus (Mouse).
• Sequence Length: 224
• Subcellular Localization: Cytoplasm . Nucleus . Cell junction, synapse, postsynaptic cell membrane .
• Protein Description: Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation..
• Protein Sequence: MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
173	Phosphorylation	QVARKQDTRQTATFR HHHHHCCCHHCCHHH	23.37	28576409
176	Phosphorylation	RKQDTRQTATFRQQP HHCCCHHCCHHHCCC	25.11	28576409
178	Phosphorylation	QDTRQTATFRQQPPP CCCHHCCHHHCCCCC	23.80	28576409
212	Phosphorylation	LCKAKSRSRNPKKPK HHHHHCCCCCCCCCC	43.42	28059163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZC4H2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZC4H2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZC4H2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ZC4H2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.