ZBT8B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT8B_HUMAN
• UniProt AC: Q8NAP8
• Protein Name: Zinc finger and BTB domain-containing protein 8B
• Gene Name: ZBTB8B
• Organism: Homo sapiens (Human).
• Sequence Length: 495
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDDKPQIQPNLSDRETLT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
120	Phosphorylation	FCKTYIRSSLDICRK HHHHHHHHHHHHHHH	26.20	-
121	Phosphorylation	CKTYIRSSLDICRKM HHHHHHHHHHHHHHH	21.88	-
168	Phosphorylation	PSSGREGTSCGTKSL CCCCCCCCCCCCCCC	18.98	29449344
169	Phosphorylation	SSGREGTSCGTKSLV CCCCCCCCCCCCCCC	22.77	29449344
172	Phosphorylation	REGTSCGTKSLVSSP CCCCCCCCCCCCCCC	23.06	29449344
174	Phosphorylation	GTSCGTKSLVSSPAE CCCCCCCCCCCCCCC	33.56	29449344
177	Phosphorylation	CGTKSLVSSPAEGEK CCCCCCCCCCCCCCC	35.58	29449344
178	Phosphorylation	GTKSLVSSPAEGEKS CCCCCCCCCCCCCCC	22.20	29449344
406	Phosphorylation	ICKGCRRTFTSHLSQ EECCCCHHHHHHHHH	16.35	25278378
408	Phosphorylation	KGCRRTFTSHLSQGL CCCCHHHHHHHHHHH	18.02	25278378
409	Phosphorylation	GCRRTFTSHLSQGLR CCCHHHHHHHHHHHH	20.45	25278378
412	Phosphorylation	RTFTSHLSQGLRRFG HHHHHHHHHHHHHCC	19.44	25278378

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT8B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT8B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT8B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZBT8B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.