ZBT39_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT39_HUMAN
• UniProt AC: O15060
• Protein Name: Zinc finger and BTB domain-containing protein 39
• Gene Name: ZBTB39
• Organism: Homo sapiens (Human).
• Sequence Length: 712
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGMRIKLQSTNHPNNLLKELNKCRLSETMCDVTIVVGSRSFPAHKAVLACAAGYFQNLFLNTGLDAARTYVVDFITPANFEKVLSFVYTSELFTDLINVGVIYEVAERLGMEDLLQACHSTFPDLESTARAKPLTSTSESHSGTLSCPSAEPAHPLGELRGGGDYLGADRNYVLPSDAGGSYKEEEKNVASDANHSLHLPQPPPPPPKTEDHDTPAPFTSIPSMMTQPLLGTVSTGIQTSTSSCQPYKVQSNGDFSKNSFLTPDNAVDITTGTNSCLSNSEHSKDPGFGQMDELQLEDLGDDDLQFEDPAEDIGTTEEVIELSDDSEDELAFGENDNRENKAMPCQVCKKVLEPNIQLIRQHARDHVDLLTGNCKVCETHFQDRNSRVTHVLSHIGIFLFSCDMCETKFFTQWQLTLHRRDGIFENNIIVHPNDPLPGKLGLFSGAASPELKCAACGKVLAKDFHVVRGHILDHLNLKGQACSVCDQRHLNLCSLMWHTLSHLGISVFSCSVCANSFVDWHLLEKHMAVHQSLEDALFHCRLCSQSFKSEAAYRYHVSQHKCNSGLDARPGFGLQHPALQKRKLPAEEFLGEELALQGQPGNSKYSCKVCGKRFAHTSEFNYHRRIHTGEKPYQCKVCHKFFRGRSTIKCHLKTHSGALMYRCTVCGHYSSTLNLMSKHVGVHKGSLPPDFTIEQTFMYIIHSKEADKNPDS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
85	Phosphorylation	ANFEKVLSFVYTSEL CCHHHHHHHHHCHHH	18.69	-
89	Phosphorylation	KVLSFVYTSELFTDL HHHHHHHCHHHHHHH	15.49	-
132	Ubiquitination	LESTARAKPLTSTSE HHHHHCCCCCCCCCC	34.70	-
172	Phosphorylation	YLGADRNYVLPSDAG CCCCCCCEECCCCCC	12.31	27642862
183	Sumoylation	SDAGGSYKEEEKNVA CCCCCCCCHHHHCCC	61.42	28112733
256	Phosphorylation	VQSNGDFSKNSFLTP EECCCCCCCCCCCCC	35.35	-
349	Ubiquitination	AMPCQVCKKVLEPNI CCCHHHHHHHHHCCH	47.24	29967540
350	Ubiquitination	MPCQVCKKVLEPNIQ CCHHHHHHHHHCCHH	47.10	29967540
439	Sumoylation	PNDPLPGKLGLFSGA CCCCCCCCCCCCCCC	37.13	28112733
448	Phosphorylation	GLFSGAASPELKCAA CCCCCCCCHHHHHHH	20.55	24719451
628	Phosphorylation	NYHRRIHTGEKPYQC CCCCCCCCCCCCCCC	44.67	28111955
656	Phosphorylation	KCHLKTHSGALMYRC EEEEEECCCEEEEEE	30.87	28555341
669	Phosphorylation	RCTVCGHYSSTLNLM EEEECCCHHHHHHHH	6.93	-
670	Phosphorylation	CTVCGHYSSTLNLMS EEECCCHHHHHHHHH	15.92	27134283
671	Phosphorylation	TVCGHYSSTLNLMSK EECCCHHHHHHHHHH	29.73	27134283
672	Phosphorylation	VCGHYSSTLNLMSKH ECCCHHHHHHHHHHC	17.45	27134283

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT39_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT39_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT39_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NARFL_HUMAN	NARFL	physical	28514442
FOXK2_HUMAN	FOXK2	physical	28514442
FOXK1_HUMAN	FOXK1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.