ZBT34_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT34_HUMAN
• UniProt AC: Q8NCN2
• Protein Name: Zinc finger and BTB domain-containing protein 34
• Gene Name: ZBTB34
• Organism: Homo sapiens (Human).
• Sequence Length: 500
• Subcellular Localization: Nucleus .
• Protein Description: May be a transcriptional repressor..
• Protein Sequence: MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Ubiquitination	NELRLQGKLCDIIVH HHHHHCCCCCCEEEE	32.74	-
119	Phosphorylation	QCVIDKCTQILESIH HHHHHHHHHHHHHHH	25.12	25690035
124	Phosphorylation	KCTQILESIHSKISV HHHHHHHHHHCCCCC	23.35	25690035
152	Ubiquitination	PESRNGVKDSSFFAN CCCCCCCCCCCCCCC	53.98	-
154	Phosphorylation	SRNGVKDSSFFANPV CCCCCCCCCCCCCCC	24.27	26074081
155	Phosphorylation	RNGVKDSSFFANPVE CCCCCCCCCCCCCCE	34.22	26074081
164	Phosphorylation	FANPVEISPPYCSQG CCCCCEECCCCCCCC	13.30	23401153
167	Phosphorylation	PVEISPPYCSQGRQP CCEECCCCCCCCCCC	14.23	26074081
169	Phosphorylation	EISPPYCSQGRQPTA EECCCCCCCCCCCCC	29.81	26074081
185	Phosphorylation	SDLRMETTPSKALRS CCCCCCCCCCHHHHH	16.56	25627689
188	Ubiquitination	RMETTPSKALRSRLQ CCCCCCCHHHHHHHH	53.28	-
188	Acetylation	RMETTPSKALRSRLQ CCCCCCCHHHHHHHH	53.28	25953088
207	Phosphorylation	SDRGSSGSVSEYEIQ CCCCCCCCEEEEEEE	25.15	24247654
235	Sumoylation	ESQITEVKVKMEKSD HHHCEEEEEEECCCC	29.88	28112733
237	Sumoylation	QITEVKVKMEKSDRP HCEEEEEEECCCCCC	35.31	28112733
332	Phosphorylation	ALSVHLHSDLQGLVQ EEEEEECHHHHHHHC	46.50	24247654
362	Methylation	SPRERSARGHWYPYN CCCHHCCCCCCCCCC	38.46	115920313
380	Phosphorylation	ICIYCGKSFNQKGSL EEEECCCCCCCCCCH	18.08	23401153
384	Ubiquitination	CGKSFNQKGSLDRHM CCCCCCCCCCHHHHH	52.12	-
386	Phosphorylation	KSFNQKGSLDRHMRL CCCCCCCCHHHHHHH	33.85	24719451
412	Ubiquitination	CGKKYTRKDQLEYHI CCCCCCCHHHHHHEE	41.86	-
423	Phosphorylation	EYHIRGHTDDKPFRC HHEECCCCCCCCEEE	49.03	28674419
426	Sumoylation	IRGHTDDKPFRCEIC ECCCCCCCCEEEEEC	49.19	28112733
459	Phosphorylation	PGVAEVRSRIESPER CCHHHHHHHCCCCCC	42.67	23403867
463	Phosphorylation	EVRSRIESPERTDVY HHHHHCCCCCCCCEE	29.68	23401153
467	Phosphorylation	RIESPERTDVYVEQK HCCCCCCCCEEEEHH	28.31	23403867
470	Phosphorylation	SPERTDVYVEQKLEN CCCCCCEEEEHHHHC	10.90	23403867
474	Sumoylation	TDVYVEQKLENDASA CCEEEEHHHHCCCCH	44.24	28112733
494	Phosphorylation	DSRMEIHTVSDAPD- CCCEEEEECCCCCC-	27.63	28450419
496	Phosphorylation	RMEIHTVSDAPD--- CEEEEECCCCCC---	29.25	28450419

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT34_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT34_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT34_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZBT34_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.