Z780A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Z780A_HUMAN
• UniProt AC: O75290
• Protein Name: Zinc finger protein 780A
• Gene Name: ZNF780A
• Organism: Homo sapiens (Human).
• Sequence Length: 641
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLENYSHLISLGSSISKPDVITLLEQEKEPWMVVRKETSRRYPDLELKYGPEKVSPENDTSEVNLPKQVIKQISTTLGIEAFYFRNDSEYRQFEGLQGYQEGNINQKMISYEKLPTHTPHASLICNTHKPYECKECGKYFSRSANLIQHQSIHTGEKPFECKECGKAFRLHIQFTRHQKFHTGEKPFECNECGKAFSLLTLLNRHKNIHTGEKLFECKECGKSFNRSSNLVQHQSIHSGVKPYECKECGKGFNRGAHLIQHQKIHSNEKPFVCKECGMAFRYHYQLIEHCQIHTGEKPFECKECGKAFTLLTKLVRHQKIHTGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECGKSFNRSSNLVQHQSIHAGIKPYECKECGKGFNRGAHLIQHQKIHSNEKPFVCRECEMAFRYHCQLIEHSRIHTGDKPFECQDCGKAFNRGSSLVQHQSIHTGEKPYECKECGKAFRLYLQLSQHQKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKLHTGEKPFECKECGKAFRLHMQLIRHQKLHTGEKPFECKECGKVFSLPTQLNRHKNIHTGEKAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
89	Phosphorylation	KYGPEKVSPENDTSE ECCCCCCCCCCCCCC	37.25	28555341
108	Phosphorylation	KQVIKQISTTLGIEA HHHHHHHHHHHCEEE	16.91	-
145	Phosphorylation	INQKMISYEKLPTHT CCCCEEEECCCCCCC	13.22	-
168	Sumoylation	THKPYECKECGKYFS CCCCCCHHHHHCCCC	44.06	-
168	Sumoylation	THKPYECKECGKYFS CCCCCCHHHHHCCCC	44.06	-
173	Phosphorylation	ECKECGKYFSRSANL CHHHHHCCCCCCCCC	7.65	-
188	Phosphorylation	IQHQSIHTGEKPFEC CCCCCCCCCCCCEEC	45.42	28348404
196	Sumoylation	GEKPFECKECGKAFR CCCCEECCCCCCEEE	49.17	-
196	Sumoylation	GEKPFECKECGKAFR CCCCEECCCCCCEEE	49.17	-
219	Ubiquitination	QKFHTGEKPFECNEC CCCCCCCCCEECCCH	57.25	-
272	Phosphorylation	VQHQSIHSGVKPYEC CCCCHHCCCCCCEEC	43.54	28555341
280	Sumoylation	GVKPYECKECGKGFN CCCCEECCCCCCCCC	44.06	-
280	Sumoylation	GVKPYECKECGKGFN CCCCEECCCCCCCCC	44.06	-
328	Phosphorylation	IEHCQIHTGEKPFEC HHCCEECCCCCCEEC	48.98	28348404
336	Sumoylation	GEKPFECKECGKAFT CCCCEECCHHHHHHH	49.17	-
336	Sumoylation	GEKPFECKECGKAFT CCCCEECCHHHHHHH	49.17	-
347	Sumoylation	KAFTLLTKLVRHQKI HHHHHHHHHHHCCCC	44.98	-
347	Sumoylation	KAFTLLTKLVRHQKI HHHHHHHHHHHCCCC	44.98	-
356	Phosphorylation	VRHQKIHTGEKPFEC HHCCCCCCCCCCEEH	50.97	29214152
384	Phosphorylation	NRHKNIHTGEKPFEC HHCCCCCCCCCCCCC	43.15	28348404
392	Sumoylation	GEKPFECKECGKSFN CCCCCCCCHHCCCCC	49.17	-
392	Sumoylation	GEKPFECKECGKSFN CCCCCCCCHHCCCCC	49.17	-
420	Sumoylation	GIKPYECKECGKGFN CCCCEECCHHCCCCC	44.06	-
420	Sumoylation	GIKPYECKECGKGFN CCCCEECCHHCCCCC	44.06	-
496	Phosphorylation	VQHQSIHTGEKPYEC CEECCCCCCCCCCCH	45.42	29496963
504	Sumoylation	GEKPYECKECGKAFR CCCCCCHHHHHHHHH	44.06	-
504	Sumoylation	GEKPYECKECGKAFR CCCCCCHHHHHHHHH	44.06	-
521	Methylation	LQLSQHQKTHTGEKP HHHHHHCCCCCCCCC	39.90	23644510
524	Phosphorylation	SQHQKTHTGEKPFEC HHHCCCCCCCCCCCH	52.87	21857030
527	Ubiquitination	QKTHTGEKPFECKEC CCCCCCCCCCCHHHH	57.25	-
527	Methylation	QKTHTGEKPFECKEC CCCCCCCCCCCHHHH	57.25	23644510
532	Sumoylation	GEKPFECKECGKFFR CCCCCCHHHHHCCCC	49.17	-
532	Sumoylation	GEKPFECKECGKFFR CCCCCCHHHHHCCCC	49.17	-
536	Ubiquitination	FECKECGKFFRRGSN CCHHHHHCCCCCCCC	53.65	-
560	Sumoylation	GKKPFECKECGKAFR CCCCEECCHHHHHHH	49.17	-
560	Sumoylation	GKKPFECKECGKAFR CCCCEECCHHHHHHH	49.17	-
580	Phosphorylation	IRHQKLHTGEKPFEC HHHCCCCCCCCCCCC	58.43	23898821
583	Ubiquitination	QKLHTGEKPFECKEC CCCCCCCCCCCCCHH	57.25	-
588	Ubiquitination	GEKPFECKECGKAFR CCCCCCCCHHHHHHH	49.17	-
588	Sumoylation	GEKPFECKECGKAFR CCCCCCCCHHHHHHH	49.17	-
588	Sumoylation	GEKPFECKECGKAFR CCCCCCCCHHHHHHH	49.17	-
608	Phosphorylation	IRHQKLHTGEKPFEC HHHCCCCCCCCCCCC	58.43	-
611	Ubiquitination	QKLHTGEKPFECKEC CCCCCCCCCCCCCCC	57.25	-
616	Sumoylation	GEKPFECKECGKVFS CCCCCCCCCCCCEEE	49.17	-
616	Sumoylation	GEKPFECKECGKVFS CCCCCCCCCCCCEEE	49.17	-
620	Acetylation	FECKECGKVFSLPTQ CCCCCCCCEEECCHH	52.33	19814703

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Z780A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Z780A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Z780A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of Z780A_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.