Z587B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Z587B_HUMAN
• UniProt AC: E7ETH6
• Protein Name: Zinc finger protein 587B
• Gene Name: ZNF587B
• Organism: Homo sapiens (Human).
• Sequence Length: 402
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAVVATLRLSAQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTLENLALMSSLGCWCGVEDEAAPSKQSIYIQRETQVRTPVTGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFVKRCKLHVSGESSVFSESGKDFLPRSGLLQQEASHTGEKSNSKTECVSPFQCGGAHYSHGDSMKHFSTKHILSQHQRLLPREECYVCCECGKSFSKYVSFSNHQRVHSGKRPYECGECEKSFSQKSSLIQHQQFHTGGKPYGCEECGKYFSLEGYLRRHQKVHAGKGPYECGECGKSFSSNVNLKSHQRIHTGERPYKCGECEKSFSRKPSLSYHQRFGRPRWVDHKDRKEFKTSLGNIVKSCLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	SEAQRCLYRDVTLEN HHHHHHHHCCCCHHH	14.37	22210691
44	Phosphorylation	RCLYRDVTLENLALM HHHHCCCCHHHHHHH	32.42	22210691
52	Phosphorylation	LENLALMSSLGCWCG HHHHHHHHHCCCCCC	24.22	22210691
87	Phosphorylation	RTPVTGVSPKKAHPC CCCCCCCCCCCCCCC	32.14	25003641
128	Sumoylation	RCEAWGNKLYDSGNF HHHHHHCCEECCCCC	44.48	-
128	Sumoylation	RCEAWGNKLYDSGNF HHHHHHCCEECCCCC	44.48	-
146	Ubiquitination	QNEHIGEKPYRGSVE CCCCCCCCCCCCCHH	41.98	-
159	Ubiquitination	VEEALFVKRCKLHVS HHHHHEEEECEEEEC	44.75	29967540
162	Sumoylation	ALFVKRCKLHVSGES HHEEEECEEEECCCC	45.73	-
162	Sumoylation	ALFVKRCKLHVSGES HHEEEECEEEECCCC	45.73	-
166	Phosphorylation	KRCKLHVSGESSVFS EECEEEECCCCHHCC	26.54	28555341
169	Phosphorylation	KLHVSGESSVFSESG EEEECCCCHHCCCCC	35.01	19053533
173	Phosphorylation	SGESSVFSESGKDFL CCCCHHCCCCCCCCC	28.79	19053533
200	Sumoylation	TGEKSNSKTECVSPF CCCCCCCCCEECCCC	53.22	-
200	Sumoylation	TGEKSNSKTECVSPF CCCCCCCCCEECCCC	53.22	-
205	Phosphorylation	NSKTECVSPFQCGGA CCCCEECCCCCCCCC	31.49	25159151
226	Sumoylation	SMKHFSTKHILSQHQ HHHHHCHHHHHHHHH	27.70	-
226	Sumoylation	SMKHFSTKHILSQHQ HHHHHCHHHHHHHHH	27.70	-
250	Phosphorylation	VCCECGKSFSKYVSF EEECCCCCHHHEEEC	21.75	24719451
253	Sumoylation	ECGKSFSKYVSFSNH CCCCCHHHEEECCCC	47.89	-
253	Sumoylation	ECGKSFSKYVSFSNH CCCCCHHHEEECCCC	47.89	-
256	Phosphorylation	KSFSKYVSFSNHQRV CCHHHEEECCCCCCC	21.62	28555341
293	Phosphorylation	IQHQQFHTGGKPYGC HHEEEECCCCCCCCC	49.25	28555341
342	Sumoylation	FSSNVNLKSHQRIHT CCCCCCCCCCCEEEC	40.46	-
342	Sumoylation	FSSNVNLKSHQRIHT CCCCCCCCCCCEEEC	40.46	-
349	Phosphorylation	KSHQRIHTGERPYKC CCCCEEECCCCCEEC	38.06	22817900
362	Phosphorylation	KCGECEKSFSRKPSL ECCCCCCCCCCCCCC	13.22	17081983
364	Phosphorylation	GECEKSFSRKPSLSY CCCCCCCCCCCCCCH	46.62	17081983
366	Sumoylation	CEKSFSRKPSLSYHQ CCCCCCCCCCCCHHH	37.45	25218447
366	Sumoylation	CEKSFSRKPSLSYHQ CCCCCCCCCCCCHHH	37.45	-
368	Phosphorylation	KSFSRKPSLSYHQRF CCCCCCCCCCHHHHH	32.74	28348404
370	Phosphorylation	FSRKPSLSYHQRFGR CCCCCCCCHHHHHCC	25.55	28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Z587B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Z587B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Z587B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of Z587B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.