Z585B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Z585B_HUMAN
• UniProt AC: Q52M93
• Protein Name: Zinc finger protein 585B
• Gene Name: ZNF585B
• Organism: Homo sapiens (Human).
• Sequence Length: 769
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MPASWTSPQKSSALAPEDHGSSYEGSVSFRDVAIDFSREEWRHLDLSQRNLYRDVMLETYSHLLSVGYQVPKPEVVMLEQGKEPWALQGERPRHSCPGEKLWDHNQHRKIIGYKPASSQDQKIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVCIECGRAFVQKPEFITHQKTHMREKPYKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLITHEKIQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSNLNIHQKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQSSHA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	SSYEGSVSFRDVAID CCCCCEEEHHEEEEE	19.09	24719451
59	Phosphorylation	YRDVMLETYSHLLSV HHHHHHHHHHHHHHC	26.77	29978859
60	Phosphorylation	RDVMLETYSHLLSVG HHHHHHHHHHHHHCC	5.68	29978859
61	Phosphorylation	DVMLETYSHLLSVGY HHHHHHHHHHHHCCC	18.32	29978859
65	Phosphorylation	ETYSHLLSVGYQVPK HHHHHHHHCCCCCCC	21.61	29978859
68	Phosphorylation	SHLLSVGYQVPKPEV HHHHHCCCCCCCCEE	12.27	29978859
187	Sumoylation	HMREKPYKCNECGKS CCCCCCCCCCCCCCC	38.83	-
187	Sumoylation	HMREKPYKCNECGKS CCCCCCCCCCCCCCC	38.83	-
200	Phosphorylation	KSFFQVSSLFRHHRI CCHHHHHHHHHCCCE	32.44	24719451
377	Phosphorylation	IIHQRIHTGEKPYEC EEEEEEECCCCCEEC	44.67	28111955
380	Ubiquitination	QRIHTGEKPYECSDC EEEECCCCCEECCCC	55.00	-
398	Phosphorylation	FTQKSALTVHQRIHT CCCCCCEEEEHHHHC	18.69	23532336
433	Phosphorylation	ITHQIIHTGEKPYKC HCCEEECCCCCCEEC	36.31	29496963
436	Ubiquitination	QIIHTGEKPYKCGHC EEECCCCCCEECCCC	55.80	-
461	Phosphorylation	HVHKRIHTGEKPYVC EEECCCCCCCCCEEE	44.67	20736484
479	O-linked_Glycosylation	GKAFTNRSNLITHQK CCCCCCCCCCEEECC	37.75	30379171
479	Phosphorylation	GKAFTNRSNLITHQK CCCCCCCCCCEEECC	37.75	25404012
483	Phosphorylation	TNRSNLITHQKTHTG CCCCCCEEECCCCCC	22.78	25404012
487	Phosphorylation	NLITHQKTHTGEKSY CCEEECCCCCCCCEE	20.35	25404012
489	Phosphorylation	ITHQKTHTGEKSYIC EEECCCCCCCCEEEE	52.87	25404012
517	Phosphorylation	ITHQRIHTGEKPYEC CCCCCCCCCCCCCCC	44.67	28111955
573	Phosphorylation	IVHQKIHTGEKPYVC EEEEEECCCCCCEEE	50.97	-
601	Phosphorylation	ITHQRIHTGEKPYEC EECCEEECCCCCEEC	44.67	27282143
604	Ubiquitination	QRIHTGEKPYECSDC CEEECCCCCEECCCC	55.00	-
629	Phosphorylation	LVHQPVHTGEKPYVC EEECCCCCCCCCEEE	47.47	-
647	O-linked_Glycosylation	GKAFSGRSNLSKHQK CCCCCCCCCCCCCCC	45.72	30379171
655	Phosphorylation	NLSKHQKTHTGEKPY CCCCCCCCCCCCCCE	20.35	21712546
657	Phosphorylation	SKHQKTHTGEKPYIC CCCCCCCCCCCCEEE	52.87	21712546
662	Phosphorylation	THTGEKPYICSECGK CCCCCCCEEECCCCC	26.15	-
685	Phosphorylation	ITHHRIHTGEKPYEC HCCCEECCCCCCEEC	44.67	27282143
688	Ubiquitination	HRIHTGEKPYECSDC CEECCCCCCEECCCC	55.00	-
698	Phosphorylation	ECSDCGKSFTKKSQL ECCCCCCCCCCHHHC	24.35	24719451
713	Phosphorylation	QVHQRIHTGEKPYVC EEECHHCCCCCCEEE	44.67	28111955
716	Sumoylation	QRIHTGEKPYVCAEC CHHCCCCCCEEEECC	42.89	-
716	Sumoylation	QRIHTGEKPYVCAEC CHHCCCCCCEEEECC	42.89	-
759	Phosphorylation	GKGFVQKSVFSVHQS CCCCCCEEEEEECCC	16.00	-
762	Phosphorylation	FVQKSVFSVHQSSHA CCCEEEEEECCCCCC	19.28	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Z585B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Z585B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Z585B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RIC8A_HUMAN	RIC8A	physical	16169070

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.