Z354A_HUMAN - dbPTM
Z354A_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID Z354A_HUMAN
UniProt AC O60765
Protein Name Zinc finger protein 354A
Gene Name ZNF354A
Organism Homo sapiens (Human).
Sequence Length 605
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MAAGQREARPQVSLTFEDVAVLFTRDEWRKLAPSQRNLYRDVMLENYRNLVSLGLPFTKPKVISLLQQGEDPWEVEKDGSGVSSLGSKSSHKTTKSTQTQDSSFQGLILKRSNRNVPWDLKLEKPYIYEGRLEKKQDKKGSFQIVSATHKKIPTIERSHKNTELSQNFSPKSVLIRQQILPREKTPPKCEIQGNSLKQNSQLLNQPKITADKRYKCSLCEKTFINTSSLRKHEKNHSGEKLFKCKECSKAFSQSSALIQHQITHTGEKPYICKECGKAFTLSTSLYKHLRTHTVEKSYRCKECGKSFSRRSGLFIHQKIHAEENPCKYNPGRKASSCSTSLSGCQRIHSRKKSYLCNECGNTFKSSSSLRYHQRIHTGEKPFKCSECGRAFSQSASLIQHERIHTGEKPYRCNECGKGFTSISRLNRHRIIHTGEKFYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQSSALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRIHTGEKPYRCEECGISFGQSSALIQHRRIHTGEKPFKCNTCGKTFRQSSSRIAHQRIHTGEKPYECNTCGKLFNHRSSLTNHYKIHIEEDP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
47PhosphorylationRDVMLENYRNLVSLG
HHHHHHHHHHHHHCC		7.4822210691
52PhosphorylationENYRNLVSLGLPFTK
HHHHHHHHCCCCCCC		21.6422210691
110SumoylationSFQGLILKRSNRNVP
CCCEEEEECCCCCCC		46.9528112733
110UbiquitinationSFQGLILKRSNRNVP
CCCEEEEECCCCCCC		46.95-
121SumoylationRNVPWDLKLEKPYIY
CCCCCCEECCCCCEE		52.7228112733
124UbiquitinationPWDLKLEKPYIYEGR
CCCEECCCCCEEECC		54.26-
135AcetylationYEGRLEKKQDKKGSF
EECCCEECCCCCCCE		55.1269697
138AcetylationRLEKKQDKKGSFQIV
CCEECCCCCCCEEEE		57.4419828243
139SumoylationLEKKQDKKGSFQIVS
CEECCCCCCCEEEEE		68.9928112733
154PhosphorylationATHKKIPTIERSHKN
CCCCCCCCCCHHHCC		38.6520393185
162PhosphorylationIERSHKNTELSQNFS
CCHHHCCCHHHCCCC		43.0127251275
165PhosphorylationSHKNTELSQNFSPKS
HHCCCHHHCCCCCHH		19.4926852163
169PhosphorylationTELSQNFSPKSVLIR
CHHHCCCCCHHHHEE		38.6828555341
171SumoylationLSQNFSPKSVLIRQQ
HHCCCCCHHHHEEEC		52.5828112733
185PhosphorylationQILPREKTPPKCEIQ
CCCCCCCCCCCCCCC		39.8225849741
214PhosphorylationKITADKRYKCSLCEK
CCCCCCCCCCCCCCC		23.3026657352
222PhosphorylationKCSLCEKTFINTSSL
CCCCCCCEEECHHHH		13.8829083192
226PhosphorylationCEKTFINTSSLRKHE
CCCEEECHHHHCHHC		18.1829083192
227PhosphorylationEKTFINTSSLRKHEK
CCEEECHHHHCHHCC		23.9229083192
265PhosphorylationIQHQITHTGEKPYIC
HHHHCCCCCCCCEEE		38.0828674419
268SumoylationQITHTGEKPYICKEC
HCCCCCCCCEEECCC		44.45-
268SumoylationQITHTGEKPYICKEC
HCCCCCCCCEEECCC		44.4528112733
268UbiquitinationQITHTGEKPYICKEC
HCCCCCCCCEEECCC		44.45-
273UbiquitinationGEKPYICKECGKAFT
CCCCEEECCCCCEEE		46.62-
308PhosphorylationKECGKSFSRRSGLFI
HHCCCCCCHHCCCEE		33.6017081983
311PhosphorylationGKSFSRRSGLFIHQK
CCCCCHHCCCEEEEE		38.4425159151
377PhosphorylationRYHQRIHTGEKPFKC
EEEEEECCCCCCEEC		44.6718669648
405PhosphorylationIQHERIHTGEKPYRC
HCCCCCCCCCCCEEC		44.6729496963
408SumoylationERIHTGEKPYRCNEC
CCCCCCCCCEECCCC		49.01-
408UbiquitinationERIHTGEKPYRCNEC
CCCCCCCCCEECCCC		49.01-
408SumoylationERIHTGEKPYRCNEC
CCCCCCCCCEECCCC		49.01-
433PhosphorylationNRHRIIHTGEKFYNC
CCCEEEECCCCEECC		36.3127251275
478PhosphorylationCGKAFRQSSALIQHQ
CCHHHHHHHHHHHHH		17.2128555341
495SumoylationHTGERPYKCNECGKT
CCCCCCEECCCCCCE		33.01-
495SumoylationHTGERPYKCNECGKT
CCCCCCEECCCCCCE		33.01-
517PhosphorylationSNHQRIHTGEKPYRC
CCCCCCCCCCCCCCC		44.6729496963
520SumoylationQRIHTGEKPYRCEEC
CCCCCCCCCCCCCCC		49.01-
520UbiquitinationQRIHTGEKPYRCEEC
CCCCCCCCCCCCCCC		49.01-
520SumoylationQRIHTGEKPYRCEEC
CCCCCCCCCCCCCCC		49.01-
545PhosphorylationIQHRRIHTGEKPFKC
HCCCEECCCCCCEEC		44.6718669648
573PhosphorylationIAHQRIHTGEKPYEC
HCCCCCCCCCCCEEC		44.6728111955
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of Z354A_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of Z354A_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of Z354A_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HDAC4_HUMANHDAC4physical
12943985
TIF1B_MOUSETrim28physical
8986806
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of Z354A_HUMAN

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Related Literatures of Post-Translational Modification

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