dbPTM

YPT5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YPT5_SCHPO
UniProt AC	P36586
Protein Name	GTP-binding protein ypt5
Gene Name	ypt5
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	211
Subcellular Localization	Cell membrane Lipid-anchor Cytoplasmic side .
Protein Description	Protein transport. Probably involved in vesicular traffic (By similarity)..
Protein Sequence	MASNTAPKNVVTINQKLVLLGDSAVGKSSLVLRFVKDQFDDYRESTIGAAFLTQTLPIDENTSVKLEIWDTAGQERYKSLAPMYYRNANCAIVVYDITQAASLEKAKSWIKELQRQAPEGIVIALAGNKLDLAQERRAVEKADAEAYAAEANLLFFETSAKTAENVNELFTAIAKKLPLEDKLNQARGAVNRGVNLSEARPAAQPSGSCSC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
209	Geranylgeranylation	AAQPSGSCSC----- CCCCCCCCCC-----	5.70	8226998
209	Geranylgeranylation	AAQPSGSCSC----- CCCCCCCCCC-----	5.70	8226998
210	Phosphorylation	AQPSGSCSC------ CCCCCCCCC------	25.26	29996109
211	Methylation	QPSGSCSC------- CCCCCCCC-------	8.30	8226998
211	Geranylgeranylation	QPSGSCSC------- CCCCCCCC-------	8.30	8226998
211	Geranylgeranylation	QPSGSCSC------- CCCCCCCC-------	8.30	8226998

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YPT5_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YPT5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YPT5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YPT5_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YPT5_SCHPO

Related Literatures of Post-Translational Modification

Prenylation
Reference	PubMed
"Post-translational processing of Schizosaccharomyces pombe YPT5protein. In vitro and in vivo analysis of processing mutants."; Giannakouros T., Newman C.M., Craighead M.W., Armstrong J.,Magee A.I.; J. Biol. Chem. 268:24467-24474(1993). Cited for: ISOPRENYLATION AT CYS-209 AND CYS-211.	8226998 [Abstract]