YP13B_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YP13B_YEAST
• UniProt AC: P0C2J0
• Protein Name: Transposon Ty1-PR2 Gag-Pol polyprotein
• Gene Name: TY1B-PR2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1756
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity).; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)..
• Protein Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRPITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMNTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MESQQLSN -------CCCCCCCC	46.79	-
13	Phosphorylation	LSNYPHISHGSACAS CCCCCCCCCCCCCCC	20.82	15665377
16	Phosphorylation	YPHISHGSACASVTS CCCCCCCCCCCCCCC	18.10	28889911
20	Phosphorylation	SHGSACASVTSKEVH CCCCCCCCCCCCCCC	26.30	28889911
22	Phosphorylation	GSACASVTSKEVHTN CCCCCCCCCCCCCCC	31.42	28889911
23	Phosphorylation	SACASVTSKEVHTNQ CCCCCCCCCCCCCCC	25.35	19823750
24	Ubiquitination	ACASVTSKEVHTNQD CCCCCCCCCCCCCCC	55.16	17644757
28	Phosphorylation	VTSKEVHTNQDPLDV CCCCCCCCCCCCCCC	39.49	28889911
36	Phosphorylation	NQDPLDVSASKIQEY CCCCCCCCHHHHHHH	26.88	25521595
38	Phosphorylation	DPLDVSASKIQEYDK CCCCCCHHHHHHHHH	23.84	25521595
39	Ubiquitination	PLDVSASKIQEYDKA CCCCCHHHHHHHHHH	48.39	24961812
43	Phosphorylation	SASKIQEYDKASTKA CHHHHHHHHHHCCCC	13.33	22890988
45	Ubiquitination	SKIQEYDKASTKANS HHHHHHHHHCCCCCC	43.25	15699485
47	Phosphorylation	IQEYDKASTKANSQQ HHHHHHHCCCCCCCC	35.86	25533186
48	Phosphorylation	QEYDKASTKANSQQT HHHHHHCCCCCCCCC	38.75	22890988
71	Phosphorylation	PENPHHASPQPASVP CCCCCCCCCCCCCCC	21.51	28889911
145	Phosphorylation	GTPLSTPSPESGNTF CCCCCCCCCCCCCCC	41.19	28889911
157	Phosphorylation	NTFTDSSSADSDMTS CCCCCCCCCCCCCCC	39.79	28889911
160	Phosphorylation	TDSSSADSDMTSTKK CCCCCCCCCCCCCCC	29.06	16445868
166	Ubiquitination	DSDMTSTKKYVRPPP CCCCCCCCCCCCCCC	41.70	15699485
167	Ubiquitination	SDMTSTKKYVRPPPM CCCCCCCCCCCCCCC	49.41	17644757
176	Phosphorylation	VRPPPMLTSPNDFPN CCCCCCCCCCCCCCH	35.57	17330950
177	Phosphorylation	RPPPMLTSPNDFPNW CCCCCCCCCCCCCHH	20.11	17330950
186	Ubiquitination	NDFPNWVKTYIKFLQ CCCCHHHHHHHHHHH	27.50	17644757
190	Ubiquitination	NWVKTYIKFLQNSNL HHHHHHHHHHHCCCC	29.61	17644757
203	Phosphorylation	NLGGIIPTVNGKPVR CCCCEEECCCCEECC	19.05	24909858
207	Ubiquitination	IIPTVNGKPVRPITD EEECCCCEECCCCCH	34.83	23749301
250	Ubiquitination	VDYTDIMKILSKSIE CCHHHHHHHHHHHHH	40.61	24961812
255	Phosphorylation	IMKILSKSIEKMQSD HHHHHHHHHHHHHHC	32.38	21440633
261	Phosphorylation	KSIEKMQSDTQEAND HHHHHHHHCCHHHHH	38.84	28132839
263	Phosphorylation	IEKMQSDTQEANDIV HHHHHHCCHHHHHHH	33.29	28132839
280	Phosphorylation	ANLQYNGSTPADAFE HHCEECCCCHHHHHH	27.81	28889911
281	Phosphorylation	NLQYNGSTPADAFET HCEECCCCHHHHHHH	24.72	27214570
289	Ubiquitination	PADAFETKVTNIIDR HHHHHHHHHHHHHHH	39.60	17644757
307	Ubiquitination	NGIHINNKVACQLIM CCCCCCCHHHHHHHH	27.07	17644757
318	Phosphorylation	QLIMRGLSGEYKFLR HHHHCCCCCCHHHHH	32.19	21440633
322	Ubiquitination	RGLSGEYKFLRYTRH CCCCCCHHHHHHHCH	33.35	23749301
353	Phosphorylation	IYEEQQGSRNSKPNY HHHHHCCCCCCCCCC	24.77	28889911
357	Ubiquitination	QQGSRNSKPNYRRNP HCCCCCCCCCCCCCC	40.61	22817900
365	Phosphorylation	PNYRRNPSDEKNDSR CCCCCCCCCCCCCCC	63.05	28889911
371	Phosphorylation	PSDEKNDSRSYTNTT CCCCCCCCCCCCCCC	32.30	17287358
373	Phosphorylation	DEKNDSRSYTNTTKP CCCCCCCCCCCCCCC	40.02	25521595
374	Phosphorylation	EKNDSRSYTNTTKPK CCCCCCCCCCCCCCE	11.69	22890988
375	Phosphorylation	KNDSRSYTNTTKPKV CCCCCCCCCCCCCEE	27.60	21551504
377	Phosphorylation	DSRSYTNTTKPKVIA CCCCCCCCCCCEEEE	28.53	22890988
378	Phosphorylation	SRSYTNTTKPKVIAR CCCCCCCCCCEEEEC	47.63	22890988
379	Ubiquitination	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	22817900
381	Ubiquitination	YTNTTKPKVIARNPQ CCCCCCCEEEECCCC	48.07	22817900
397	Phosphorylation	TNNSKSKTARAHNVS CCCCCCCCCHHCCCC	28.59	21551504
404	Phosphorylation	TARAHNVSTSNNSPS CCHHCCCCCCCCCCC	31.28	25533186
405	Phosphorylation	ARAHNVSTSNNSPST CHHCCCCCCCCCCCC	31.06	25533186
406	Phosphorylation	RAHNVSTSNNSPSTD HHCCCCCCCCCCCCC	26.89	21551504
409	Phosphorylation	NVSTSNNSPSTDNDS CCCCCCCCCCCCCCC	25.20	17330950
411	Phosphorylation	STSNNSPSTDNDSIS CCCCCCCCCCCCCCC	48.49	17330950
412	Phosphorylation	TSNNSPSTDNDSISK CCCCCCCCCCCCCCC	42.05	17330950
416	Phosphorylation	SPSTDNDSISKSTTE CCCCCCCCCCCCCCC	34.71	21551504
418	Phosphorylation	STDNDSISKSTTEPI CCCCCCCCCCCCCCE	25.22	25533186
419	Ubiquitination	TDNDSISKSTTEPIQ CCCCCCCCCCCCCEE	50.59	23749301
420	Phosphorylation	DNDSISKSTTEPIQL CCCCCCCCCCCCEEC	33.50	24909858
421	Phosphorylation	NDSISKSTTEPIQLN CCCCCCCCCCCEECC	38.63	28889911
422	Phosphorylation	DSISKSTTEPIQLNN CCCCCCCCCCEECCC	47.02	21551504
430	Ubiquitination	EPIQLNNKHDLHLGQ CCEECCCCCCCCCCH	37.11	22817900
438	Ubiquitination	HDLHLGQKLTESTVN CCCCCCHHCCHHHCC	56.42	17644757
440	Phosphorylation	LHLGQKLTESTVNHT CCCCHHCCHHHCCCC	34.62	19779198
442	Phosphorylation	LGQKLTESTVNHTNH CCHHCCHHHCCCCCC	32.21	17330950
443	Phosphorylation	GQKLTESTVNHTNHS CHHCCHHHCCCCCCC	21.06	17330950
447	Phosphorylation	TESTVNHTNHSDDEL CHHHCCCCCCCCCCC	29.44	19779198
450	Phosphorylation	TVNHTNHSDDELPGH HCCCCCCCCCCCCCE	49.15	28889911
471	Phosphorylation	ASRTLIRSAHHIHSA CCHHHHHHHHHHHHC	25.59	30377154
477	Phosphorylation	RSAHHIHSASSNPDI HHHHHHHHCCCCCCC	29.28	24909858
479	Phosphorylation	AHHIHSASSNPDINV HHHHHHCCCCCCCCC	33.39	19779198
480	Phosphorylation	HHIHSASSNPDINVV HHHHHCCCCCCCCCC	52.69	24909858
491	Ubiquitination	INVVDAQKRNIPINA CCCCCHHHCCCCCCE	49.48	23749301
511	Ubiquitination	FHFQDNTKTSIKVLH EEEECCCCCEEEEEE	46.67	17644757
515	Ubiquitination	DNTKTSIKVLHTPNI CCCCCEEEEEECCCH	38.21	17644757
543	Ubiquitination	DITACFTKNVLERSD CHHHHCCCCHHHCCC	25.47	17644757
559	Ubiquitination	TVLAPIVKYGDFYWV EEEEEEEECCCEEEE	44.21	17644757
568	Ubiquitination	GDFYWVSKKYLLPSN CCEEEEECEEECCCC	35.50	17644757
569	Ubiquitination	DFYWVSKKYLLPSNI CEEEEECEEECCCCC	33.36	24961812
574	Phosphorylation	SKKYLLPSNISVPTI ECEEECCCCCCCCCC	46.92	30377154
577	Phosphorylation	YLLPSNISVPTINNV EECCCCCCCCCCCCC	26.71	25521595
580	Phosphorylation	PSNISVPTINNVHTS CCCCCCCCCCCCCCC	33.89	28889911
586	Phosphorylation	PTINNVHTSESTRKY CCCCCCCCCCCCCCC	29.88	25521595
589	Phosphorylation	NNVHTSESTRKYPYP CCCCCCCCCCCCCCH	33.02	25521595
592	Ubiquitination	HTSESTRKYPYPFIH CCCCCCCCCCCHHHH	51.14	17644757
615	Ubiquitination	QTIRYSLKNNTITYF CEEEEECCCCEEEEE	42.06	15699485
644	Ubiquitination	CPDCLIGKSTKHRHI CCCCEECCCCCCCCC	48.21	15699485
657	Ubiquitination	HIKGSRLKYQNSYEP CCCCCCCCCCCCCCC	43.62	17644757
681	Ubiquitination	GPVHNLPKSAPSYFI CCCCCCCCCCCCEEE	63.52	17644757
696	Ubiquitination	SFTDETTKFRWVYPL EEECCCCCEEEEEEC	40.11	17644757
723	Ubiquitination	TTILAFIKNQFQASV HHHHHHHHHHHHCEE	37.94	15699485
748	Acetylation	YTNRTLHKFLEKKNG HHHHHHHHHHHHHCC	55.55	25381059
748	Ubiquitination	YTNRTLHKFLEKKNG HHHHHHHHHHHHHCC	55.55	23749301
753	Ubiquitination	LHKFLEKKNGITPCY HHHHHHHHCCCCCCE	51.54	17644757
813	Phosphorylation	IVRNSLASPKSKKSA HHHHHCCCCCCHHHH	37.85	25752575
851	Ubiquitination	NDHNPNSKIHPRGIP CCCCCCCCCCCCCCC	52.23	23749301
879	Ubiquitination	IIYLPSLKKTVDTTN EEEECCCCEEECCCC	51.22	17644757
880	Ubiquitination	IYLPSLKKTVDTTNY EEECCCCEEECCCCE	60.10	17644757
881	Phosphorylation	YLPSLKKTVDTTNYV EECCCCEEECCCCEE	23.25	27017623
884	Phosphorylation	SLKKTVDTTNYVILQ CCCEEECCCCEEEEC	16.77	27017623
885	Phosphorylation	LKKTVDTTNYVILQG CCEEECCCCEEEECC	21.79	27017623
887	Phosphorylation	KTVDTTNYVILQGKE EEECCCCEEEECCCH	6.18	27017623
893	Ubiquitination	NYVILQGKESRLDQF CEEEECCCHHHHHHC	39.29	24961812
895	Phosphorylation	VILQGKESRLDQFNY EEECCCHHHHHHCCC	41.45	27017623
906	Phosphorylation	QFNYDALTFDEDLNR HCCCCCCCCCHHHHH	30.66	27017623
915	Phosphorylation	DEDLNRLTASYHSFI CHHHHHHHHHHHHHH	15.43	19779198
937	Phosphorylation	SNDLNIESDHDFQSD CCCCCCCCCCCHHHC	36.13	28889911
943	Phosphorylation	ESDHDFQSDIELHPE CCCCCHHHCCCCCCC	40.32	28889911
957	Phosphorylation	EQPRNVLSKAVSPTD CCCCCHHHHCCCCCC	17.81	17330950
958	Ubiquitination	QPRNVLSKAVSPTDS CCCCHHHHCCCCCCC	48.96	17644757
961	Phosphorylation	NVLSKAVSPTDSTPP CHHHHCCCCCCCCCC	27.26	17330950
963	Phosphorylation	LSKAVSPTDSTPPST HHHCCCCCCCCCCCC	34.77	17330950
965	Phosphorylation	KAVSPTDSTPPSTHT HCCCCCCCCCCCCCC	45.34	17330950
966	Phosphorylation	AVSPTDSTPPSTHTE CCCCCCCCCCCCCCH	41.87	17330950
969	Phosphorylation	PTDSTPPSTHTEDSK CCCCCCCCCCCHHCC	33.74	22890988
970	Phosphorylation	TDSTPPSTHTEDSKR CCCCCCCCCCHHCCC	38.29	22890988
972	Phosphorylation	STPPSTHTEDSKRVS CCCCCCCCHHCCCCC	41.39	22890988
975	Phosphorylation	PSTHTEDSKRVSKTN CCCCCHHCCCCCCCC	19.01	22890988
976	Ubiquitination	STHTEDSKRVSKTNI CCCCHHCCCCCCCCC	69.96	22817900
979	Phosphorylation	TEDSKRVSKTNIRAP CHHCCCCCCCCCCCC	37.48	21440633
980	Ubiquitination	EDSKRVSKTNIRAPR HHCCCCCCCCCCCCC	42.61	22817900
981	Phosphorylation	DSKRVSKTNIRAPRE HCCCCCCCCCCCCCC	28.50	28889911
994	Phosphorylation	REVDPNISESNILPS CCCCCCCCHHHCCCC	41.43	25533186
996	Phosphorylation	VDPNISESNILPSKK CCCCCCHHHCCCCCC	23.52	22890988
1001	Phosphorylation	SESNILPSKKRSSTP CHHHCCCCCCCCCCC	47.57	22890988
1002	Ubiquitination	ESNILPSKKRSSTPQ HHHCCCCCCCCCCCC	50.71	17644757
1003	Ubiquitination	SNILPSKKRSSTPQI HHCCCCCCCCCCCCC	62.95	17644757
1005	Phosphorylation	ILPSKKRSSTPQISN CCCCCCCCCCCCCCC	47.66	17330950
1006	Phosphorylation	LPSKKRSSTPQISNI CCCCCCCCCCCCCCC	48.41	17330950
1007	Phosphorylation	PSKKRSSTPQISNIE CCCCCCCCCCCCCCE	22.06	17330950
1011	Phosphorylation	RSSTPQISNIESTGS CCCCCCCCCCEECCC	26.89	22890988
1015	Phosphorylation	PQISNIESTGSGGMH CCCCCCEECCCCCCC	33.98	22890988
1016	Phosphorylation	QISNIESTGSGGMHK CCCCCEECCCCCCCC	23.68	22890988
1018	Phosphorylation	SNIESTGSGGMHKLN CCCEECCCCCCCCCC	32.06	22890988
1023	Ubiquitination	TGSGGMHKLNVPLLA CCCCCCCCCCCCEEE	32.63	17644757
1033	Phosphorylation	VPLLAPMSQSNTHES CCEEEECCCCCCCCC	29.42	28889911
1035	Phosphorylation	LLAPMSQSNTHESSH EEEECCCCCCCCCCC	36.07	19779198
1037	Phosphorylation	APMSQSNTHESSHAS EECCCCCCCCCCCCC	32.06	28889911
1040	Phosphorylation	SQSNTHESSHASKSK CCCCCCCCCCCCCCC	21.59	21440633
1044	Phosphorylation	THESSHASKSKDFRH CCCCCCCCCCCCCCC	31.85	28889911
1045	Ubiquitination	HESSHASKSKDFRHS CCCCCCCCCCCCCCC	63.41	17644757
1046	Phosphorylation	ESSHASKSKDFRHSD CCCCCCCCCCCCCCC	34.66	28889911
1047	Ubiquitination	SSHASKSKDFRHSDS CCCCCCCCCCCCCCC	65.70	15699485
1052	Phosphorylation	KSKDFRHSDSYSENE CCCCCCCCCCCCCCC	24.81	17330950
1054	Phosphorylation	KDFRHSDSYSENETN CCCCCCCCCCCCCCC	33.31	17330950
1055	Phosphorylation	DFRHSDSYSENETNH CCCCCCCCCCCCCCC	25.62	17330950
1056	Phosphorylation	FRHSDSYSENETNHT CCCCCCCCCCCCCCC	37.59	17330950
1060	Phosphorylation	DSYSENETNHTNVPI CCCCCCCCCCCCCCC	43.83	17330950
1063	Phosphorylation	SENETNHTNVPISST CCCCCCCCCCCCCCC	39.73	22890988
1068	Phosphorylation	NHTNVPISSTGGTNN CCCCCCCCCCCCCCC	18.77	22890988
1069	Phosphorylation	HTNVPISSTGGTNNK CCCCCCCCCCCCCCC	31.62	22890988
1070	Phosphorylation	TNVPISSTGGTNNKT CCCCCCCCCCCCCCC	32.60	22890988
1073	Phosphorylation	PISSTGGTNNKTVPQ CCCCCCCCCCCCCCC	36.64	22890988
1076	Ubiquitination	STGGTNNKTVPQISD CCCCCCCCCCCCCCC	53.63	17644757
1077	Phosphorylation	TGGTNNKTVPQISDQ CCCCCCCCCCCCCCH	39.27	28132839
1082	Phosphorylation	NKTVPQISDQETEKR CCCCCCCCCHHHHHH	28.17	17330950
1086	Phosphorylation	PQISDQETEKRIIHR CCCCCHHHHHHHHCC	40.97	22890988
1088	Ubiquitination	ISDQETEKRIIHRSP CCCHHHHHHHHCCCC	57.21	22817900
1094	Phosphorylation	EKRIIHRSPSIDASP HHHHHCCCCCCCCCC	14.61	17330950
1096	Phosphorylation	RIIHRSPSIDASPPE HHHCCCCCCCCCCCC	34.05	17330950
1100	Phosphorylation	RSPSIDASPPENNSS CCCCCCCCCCCCCCC	36.92	21551504
1106	Phosphorylation	ASPPENNSSHNIVPI CCCCCCCCCCCEEEC	44.55	21551504
1107	Phosphorylation	SPPENNSSHNIVPIK CCCCCCCCCCEEECC	23.76	22890988
1114	Ubiquitination	SHNIVPIKTPTTVSE CCCEEECCCCCCCCC	42.24	15699485
1141	Phosphorylation	LPDLPPESPTEFPDP CCCCCCCCCCCCCCC	42.78	23607784
1143	Phosphorylation	DLPPESPTEFPDPFK CCCCCCCCCCCCCCC	60.58	21440633
1157	Phosphorylation	KELPPINSHQTNSSL CCCCCCCCCCCCCCC	20.07	28889911
1160	Phosphorylation	PPINSHQTNSSLGGI CCCCCCCCCCCCCCC	31.48	28889911
1162	Phosphorylation	INSHQTNSSLGGIGD CCCCCCCCCCCCCCC	30.26	21440633
1163	Phosphorylation	NSHQTNSSLGGIGDS CCCCCCCCCCCCCCC	32.86	25752575
1174	Phosphorylation	IGDSNAYTTINSKKR CCCCCCCCEECCCCC	20.84	19779198
1179	Ubiquitination	AYTTINSKKRSLEDN CCCEECCCCCCCCCC	47.95	15699485
1180	Ubiquitination	YTTINSKKRSLEDNE CCEECCCCCCCCCCC	47.22	15699485
1182	Phosphorylation	TINSKKRSLEDNETE EECCCCCCCCCCCCE	45.02	17330950
1188	Phosphorylation	RSLEDNETEIKVSRD CCCCCCCCEEEEEHH	49.63	28132839
1191	Ubiquitination	EDNETEIKVSRDTWN CCCCCEEEEEHHCCC	28.11	23749301
1193	Phosphorylation	NETEIKVSRDTWNTK CCCEEEEEHHCCCCC	21.31	30377154
1200	Ubiquitination	SRDTWNTKNMRSLEP EHHCCCCCCCCCCCC	45.60	22817900
1221	Ubiquitination	IHLIAAVKAVKSIKP HHHHHHHHHHHCCCC	42.61	17644757
1243	Ubiquitination	DEAITYNKDIKEKEK CCCCCCCCCHHHHHH	50.87	23749301
1246	Ubiquitination	ITYNKDIKEKEKYIE CCCCCCHHHHHHHHH	73.24	22817900
1248	Ubiquitination	YNKDIKEKEKYIEAY CCCCHHHHHHHHHHH	55.28	22817900
1250	Ubiquitination	KDIKEKEKYIEAYHK CCHHHHHHHHHHHHH	63.70	15699485
1257	Ubiquitination	KYIEAYHKEVNQLLK HHHHHHHHHHHHHHH	51.16	15699485
1264	Ubiquitination	KEVNQLLKMNTWDTD HHHHHHHHCCCCCCC	38.40	15699485
1294	Ubiquitination	SMFIFNRKRDGTHKA EEEEEECCCCCCCCE	56.81	17644757
1386	Ubiquitination	KKSLYGLKQSGANWY HHHHHCCHHCCCCHH	37.75	15699485
1388	Phosphorylation	SLYGLKQSGANWYET HHHCCHHCCCCHHHH	37.98	19779198
1393	Phosphorylation	KQSGANWYETIKSYL HHCCCCHHHHHHHHH	11.73	19779198
1397	Ubiquitination	ANWYETIKSYLIKQC CCHHHHHHHHHHHHH	40.23	15699485
1402	Ubiquitination	TIKSYLIKQCGMEEV HHHHHHHHHHCCHHH	36.62	24961812
1441	Ubiquitination	SKDLNANKKIITTLK HCCCCCCHHHHHHHH	42.83	17644757
1442	Ubiquitination	KDLNANKKIITTLKK CCCCCCHHHHHHHHH	38.87	17644757
1448	Ubiquitination	KKIITTLKKQYDTKI HHHHHHHHHHCCCEE	35.42	17644757
1449	Ubiquitination	KIITTLKKQYDTKII HHHHHHHHHCCCEEE	58.14	17644757
1454	Ubiquitination	LKKQYDTKIINLGES HHHHCCCEEEECCCC	38.40	17644757
1475	Ubiquitination	DILGLEIKYQRGKYM EEECEEEEEECCCCC	26.42	17644757
1481	Phosphorylation	IKYQRGKYMKLGMEN EEEECCCCCCCCCCC	11.42	19779198
1483	Ubiquitination	YQRGKYMKLGMENSL EECCCCCCCCCCCCC	38.51	15699485
1493	Ubiquitination	MENSLTEKIPKLNVP CCCCCCCCCCCCCCC	60.10	23749301
1496	Ubiquitination	SLTEKIPKLNVPLNP CCCCCCCCCCCCCCC	57.05	22817900
1504	Ubiquitination	LNVPLNPKGRKLSAP CCCCCCCCCCCCCCC	70.99	22817900
1507	Ubiquitination	PLNPKGRKLSAPGQP CCCCCCCCCCCCCCC	56.30	22817900
1509	Phosphorylation	NPKGRKLSAPGQPGL CCCCCCCCCCCCCCE	35.14	28889911
1539	Ubiquitination	EKVHEMQKLIGLASY HHHHHHHHHHHHHHH	40.54	17644757
1550	Ubiquitination	LASYVGYKFRFDLLY HHHHCCHHHHHHHHH	24.92	22106047
1596	Ubiquitination	DKQLIWHKNKPTEPD CCEEEEECCCCCCCC	52.23	15699485
1598	Ubiquitination	QLIWHKNKPTEPDNK EEEEECCCCCCCCCC	59.11	15699485
1605	Ubiquitination	KPTEPDNKLVAISDA CCCCCCCCEEEEEEC	52.28	24961812
1621	Ubiquitination	YGNQPYYKSQIGNIY CCCCCCEECCCCCEE	30.00	17644757
1633	Ubiquitination	NIYLLNGKVIGGKST CEEEECCEEECCCCC	29.61	17644757
1641	Ubiquitination	VIGGKSTKASLTCTS EECCCCCCEEEEECC	42.97	15699485
1676	Ubiquitination	HLVQELNKKPITKGL HHHHHHHCCCCCCCC	72.97	15699485
1677	Ubiquitination	LVQELNKKPITKGLL HHHHHHCCCCCCCCC	40.35	15699485
1688	Ubiquitination	KGLLTDSKSTISIII CCCCCCCCCEEEEEE	55.20	17644757
1701	Ubiquitination	IISNNEEKFRNRFFG EECCCHHHHHHHHCC	43.37	17644757
1710	Ubiquitination	RNRFFGTKAMRLRDE HHHHCCHHHCHHHHC	40.33	23749301
1731	Ubiquitination	HVCYIETKKNIADVM EEEEEECCCCHHHHH	30.91	17644757
1732	Ubiquitination	VCYIETKKNIADVMT EEEEECCCCHHHHHC	62.09	23749301
1739	Phosphorylation	KNIADVMTKPLPIKT CCHHHHHCCCCCCCC	29.38	20377248
1740	Ubiquitination	NIADVMTKPLPIKTF CHHHHHCCCCCCCCC	26.85	23749301
1745	Ubiquitination	MTKPLPIKTFKLLTN HCCCCCCCCCHHHHC	46.07	22817900
1748	Ubiquitination	PLPIKTFKLLTNKWI CCCCCCCHHHHCCCC	48.06	15699485

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YP13B_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YP13B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YP13B_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YP13B_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
PubMed: 15665377

Phosphorylation

"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
PubMed: 15665377