dbPTM

YOCE_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YOCE_SCHPO
UniProt AC	O74400
Protein Name	Uncharacterized RNA-binding protein C4F6.14
Gene Name	SPBC4F6.14
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	674
Subcellular Localization	Nucleus, nucleolus .
Protein Description
Protein Sequence	MNSNSTLFVRNLAFQTKQDDLTNFFSDVGPIKHAVVVTNPETGENRGYGFVTFSMLEDAQRAAKELKNKKLHGRILRLDFATPRKRSEVDTDQNKAVKKTIRQDNRPRLIIRNLPWSIKKPQHLEPHFSKFGKVREIKIPTKGGGRMCGFAFVWMKDRKAAEEAMNSLNGTEIDGRPIAVDWAVSKDAFEATTLKDASSEEENKEFVSDEGHSIVTEDASADSESEEEVDGHSEGKELAGESEEEGSNVDDVEDSGDSSSDKNSINHEIRDNEGLEDTVFVRNLLFECTEQELYNHFRQFGPLAYAKLVKDPATDRSLGRGFIKFRYEKDCQNCLEMASQLPTQEPTEAEKRFLPSVLVDEGIDTDSVSSRFLLHGRLLKVTSAVTRKEASDINQKSLQERKQKMGKGVDRRHLFLLNEGKIAADHPLFNSLSETDKTLRSQSIAQRKKLLEKNPTLHLSLNRLSIRNISRHIDPKILAMLGRQAIRGFMDDVSKGLRANITEEEENLDKGHRLKRGKSGGVLKQAKVETEKAGAGRSKGFGFMQFISHKYALMALRWLNGREITVKKIIDAEIEWARKHKIPEPQLPNIDYNDRPRRLIVEFAIENIQVVKRRQEKEKSFRQKAKQLKQQEDEDNLKRKRSESDVEDNEAKEKQAKVARIIQRKRMKRRSRKN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
220	Phosphorylation	SIVTEDASADSESEE CEECCCCCCCCCCCC	44.95	21712547
223	Phosphorylation	TEDASADSESEEEVD CCCCCCCCCCCCHHC	42.62	28889911
225	Phosphorylation	DASADSESEEEVDGH CCCCCCCCCCHHCCC	55.02	28889911
242	Phosphorylation	GKELAGESEEEGSNV HHHHCCCCCCCCCCC	49.76	28889911
247	Phosphorylation	GESEEEGSNVDDVED CCCCCCCCCCCCCCC	36.64	28889911
264	Phosphorylation	DSSSDKNSINHEIRD CCCCCCCCCCHHHHC	30.43	29996109
642	Phosphorylation	DNLKRKRSESDVEDN HHHHHHHCHHHHCCH	44.48	29996109
644	Phosphorylation	LKRKRSESDVEDNEA HHHHHCHHHHCCHHH	48.48	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YOCE_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YOCE_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YOCE_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YOCE_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YOCE_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-223; SER-225; SER-242AND SER-247, AND MASS SPECTROMETRY.	18257517 [Abstract]