YN2B_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YN2B_SCHPO
• UniProt AC: O59746
• Protein Name: Uncharacterized transcriptional regulatory protein C530.11c
• Gene Name: SPBC530.11c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 819
• Subcellular Localization: Nucleus .
• Protein Sequence: MLENSTAVHGVRLSDSPEDPFLRKRLASNTQLNQKKIRFTENENDLSPERAQKEPVSIPHGRYTWSTSPDTDSSHLPSTPPTVDIPFHHPHTIHSPTFTLSVSPDSQSSSATHQNDYISSPHADFSFSPPASKIQSHEPLNDMAAVHPLRPSHVSGPLSPPEPKAASVDHSINPAYNASFRLPDGPLWTEGSENLPSLDIQLQLAHIYFIYAHGQPYVLFHRDSFMEALKSQRLPPVLVLAMCAVAIRFWQTDKYDKNELFEQWFNRASAIAMANFDKLDLVYVASFVMLSYVCAATSKYWMFAGMAIRMVVALHPNKTPNLPYYDRPDSPLPFEIRVQLTRRLFWDCFMLDRLNSLYCNTQFLNLEDIHVPLPMRETLFMYKAHAVTETLTGKPSSPDSFTNANPTTAPIVSRNAQDNMGMLAYMIRMVSIWGRVVRCLKSYSQKQSNPYPFWHAKSTFKQLDQELYEWEKNLPNRLRYSRQTLLSYHMMGQGGQFACLHLIFLQIHLYVHRYAASISSVPFSHVKSPPTVFENQSAVLASQCANAICRIIQDCTELSISLAAPFTASSAYLAGTVLLYHYITRGSEVQASKAAVHLPIAKRHLAQLSVYWPALGMYAKALDAIAFHQGALVTPSVPPVIATVSKTNTTNTGVQQRGNVGVTTTGSILTQSSPALPVQPVPLAYSKPAPTTKSSLTELAYNTNVSLPPRSPGTGSLAAGNLPNEKAPSLMTMVNGGPVPGDIGEASIPVVQNLQPSTAHVDPESDLGRVIKICDWYQSPSSDVLLSKPLQLNSSEEMEQQCIDLSRHNTLLNLSSYGI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MLENSTAVHGVR ---CCCCCCCCCCEE	14.36	21712547
6	Phosphorylation	--MLENSTAVHGVRL --CCCCCCCCCCEEC	44.26	21712547
14	Phosphorylation	AVHGVRLSDSPEDPF CCCCEECCCCCCCHH	26.02	29996109
16	Phosphorylation	HGVRLSDSPEDPFLR CCEECCCCCCCHHHH	27.15	28889911
28	Phosphorylation	FLRKRLASNTQLNQK HHHHHHHCCCCCCHH	45.03	24763107
30	Phosphorylation	RKRLASNTQLNQKKI HHHHHCCCCCCHHHC	31.75	21712547
40	Phosphorylation	NQKKIRFTENENDLS CHHHCCCCCCCCCCC	28.22	29996109
47	Phosphorylation	TENENDLSPERAQKE CCCCCCCCHHHHHCC	27.81	19547744
136	Phosphorylation	PPASKIQSHEPLNDM CCHHHCCCCCCCCCC	33.04	21712547
152	Phosphorylation	AVHPLRPSHVSGPLS CCCCCCHHHCCCCCC	30.04	29996109
155	Phosphorylation	PLRPSHVSGPLSPPE CCCHHHCCCCCCCCC	29.30	21712547
159	Phosphorylation	SHVSGPLSPPEPKAA HHCCCCCCCCCCCCC	41.35	21712547
167	Phosphorylation	PPEPKAASVDHSINP CCCCCCCCCCCCCCC	32.70	25720772
171	Phosphorylation	KAASVDHSINPAYNA CCCCCCCCCCCCCCC	21.43	29996109
392	Phosphorylation	HAVTETLTGKPSSPD HEEHHHCCCCCCCCC	51.05	29996109
396	Phosphorylation	ETLTGKPSSPDSFTN HHCCCCCCCCCCCCC	58.97	29996109
397	Phosphorylation	TLTGKPSSPDSFTNA HCCCCCCCCCCCCCC	41.05	25720772
400	Phosphorylation	GKPSSPDSFTNANPT CCCCCCCCCCCCCCC	37.04	29996109
402	Phosphorylation	PSSPDSFTNANPTTA CCCCCCCCCCCCCCC	37.06	29996109
711	Phosphorylation	NVSLPPRSPGTGSLA CCCCCCCCCCCCCCC	33.19	29996109
714	Phosphorylation	LPPRSPGTGSLAAGN CCCCCCCCCCCCCCC	27.29	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YN2B_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YN2B_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YN2B_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TIP20_SCHPO	drp1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16, AND MASSSPECTROMETRY.
PubMed: 18257517