YN12B_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YN12B_YEAST
• UniProt AC: Q99337
• Protein Name: Transposon Ty1-NL2 Gag-Pol polyprotein
• Gene Name: TY1B-NL2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1749
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity).; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)..
• Protein Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSDWSFYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISKSDILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHTSKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTKLSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIEQCDMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVHLNPKGKKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MESQQLSQHS -----CCCCCCCCCC	34.78	22369663
7	Phosphorylation	-MESQQLSQHSPISH -CCCCCCCCCCCCCC	22.85	22369663
10	Phosphorylation	SQQLSQHSPISHGSA CCCCCCCCCCCCHHH	19.11	22369663
13	Phosphorylation	LSQHSPISHGSACAS CCCCCCCCCHHHCCC	25.77	22369663
16	Phosphorylation	HSPISHGSACASVTS CCCCCCHHHCCCCCC	18.10	22369663
20	Phosphorylation	SHGSACASVTSKEVH CCHHHCCCCCCCCCC	26.30	22369663
22	Phosphorylation	GSACASVTSKEVHTN HHHCCCCCCCCCCCC	31.42	22369663
23	Phosphorylation	SACASVTSKEVHTNQ HHCCCCCCCCCCCCC	25.35	22369663
24	Ubiquitination	ACASVTSKEVHTNQD HCCCCCCCCCCCCCC	55.16	24961812
28	Phosphorylation	VTSKEVHTNQDPLDV CCCCCCCCCCCCCCC	39.49	28889911
36	Phosphorylation	NQDPLDVSASKIQEY CCCCCCCCHHHHHHH	26.88	25521595
38	Phosphorylation	DPLDVSASKIQEYDK CCCCCCHHHHHHHHH	23.84	25521595
39	Ubiquitination	PLDVSASKIQEYDKA CCCCCHHHHHHHHHH	48.39	24961812
43	Phosphorylation	SASKIQEYDKASTKA CHHHHHHHHHHCCCC	13.33	22890988
45	Ubiquitination	SKIQEYDKASTKANS HHHHHHHHHCCCCCC	43.25	15699485
47	Phosphorylation	IQEYDKASTKANSQQ HHHHHHHCCCCCCCC	35.86	25533186
48	Phosphorylation	QEYDKASTKANSQQT HHHHHHCCCCCCCCC	38.75	22890988
71	Phosphorylation	PENPHHASPQTAQSH CCCCCCCCCCCCCCC	17.12	28889911
74	Phosphorylation	PHHASPQTAQSHSPQ CCCCCCCCCCCCCCC	30.01	28889911
79	Phosphorylation	PQTAQSHSPQNGPYP CCCCCCCCCCCCCCC	33.17	28889911
145	Phosphorylation	GTPLSTPSPESGNTF CCCCCCCCCCCCCCC	41.19	28889911
157	Phosphorylation	NTFTDSSSADSDMTS CCCCCCCCCCCCCCC	39.79	28889911
160	Phosphorylation	TDSSSADSDMTSTKK CCCCCCCCCCCCCCC	29.06	16445868
190	Ubiquitination	NWVKTYIKFLQNSNL HHHHHHHHHHHHCCC	29.61	17644757
203	Phosphorylation	NLGGIIPTVNGKPVR CCCCEEECCCCEECE	19.05	24909858
207	Ubiquitination	IIPTVNGKPVRQITD EEECCCCEECEECCH	34.83	23749301
238	Ubiquitination	QFLPTWVKDILSVDY HCCCHHHHHHHCCCH	30.52	15699485
250	Ubiquitination	VDYTDIMKILSKSIE CCHHHHHHHHHHHHH	40.61	24961812
255	Phosphorylation	IMKILSKSIEKMQSD HHHHHHHHHHHHHHC	32.38	21440633
261	Phosphorylation	KSIEKMQSDTQEAND HHHHHHHHCCHHHHH	38.84	28132839
263	Phosphorylation	IEKMQSDTQEANDIV HHHHHHCCHHHHHHH	33.29	28132839
280	Phosphorylation	ANLQYNGSTPADAFE HHCEECCCCHHHHHH	27.81	28889911
281	Phosphorylation	NLQYNGSTPADAFET HCEECCCCHHHHHHH	24.72	27214570
289	Ubiquitination	PADAFETKVTNIIDR HHHHHHHHHHHHHHH	39.60	17644757
307	Ubiquitination	NGIHINNKVACQLIM CCCCCCCHHHHHHHH	27.07	17644757
318	Phosphorylation	QLIMRGLSGEYKFLR HHHHCCCCCCHHHHH	32.19	21440633
322	Ubiquitination	RGLSGEYKFLRYTRH CCCCCCHHHHHHHCH	33.35	23749301
353	Phosphorylation	IYEEQQGSRNSKPNY HHHHHCCCCCCCCCC	24.77	28889911
357	Ubiquitination	QQGSRNSKPNYRRNP HCCCCCCCCCCCCCC	40.61	22817900
365	Phosphorylation	PNYRRNPSDEKNDSR CCCCCCCCCCCCCCC	63.05	28889911
371	Phosphorylation	PSDEKNDSRSYTNTT CCCCCCCCCCCCCCC	32.30	17287358
373	Phosphorylation	DEKNDSRSYTNTTKP CCCCCCCCCCCCCCC	40.02	25521595
374	Phosphorylation	EKNDSRSYTNTTKPK CCCCCCCCCCCCCCE	11.69	22890988
375	Phosphorylation	KNDSRSYTNTTKPKV CCCCCCCCCCCCCEE	27.60	21551504
377	Phosphorylation	DSRSYTNTTKPKVIA CCCCCCCCCCCEEEE	28.53	22890988
378	Phosphorylation	SRSYTNTTKPKVIAR CCCCCCCCCCEEEEC	47.63	22890988
379	Ubiquitination	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	22817900
381	Ubiquitination	YTNTTKPKVIARNPQ CCCCCCCEEEECCCC	48.07	22817900
397	Phosphorylation	TNNSKSKTARAHNVS CCCCCCCCCHHCCCC	28.59	21551504
404	Phosphorylation	TARAHNVSTSNNSPS CCHHCCCCCCCCCCC	31.28	25533186
405	Phosphorylation	ARAHNVSTSNNSPST CHHCCCCCCCCCCCC	31.06	25533186
406	Phosphorylation	RAHNVSTSNNSPSTD HHCCCCCCCCCCCCC	26.89	21551504
409	Phosphorylation	NVSTSNNSPSTDNDS CCCCCCCCCCCCCCC	25.20	17330950
411	Phosphorylation	STSNNSPSTDNDSIS CCCCCCCCCCCCCCC	48.49	17330950
412	Phosphorylation	TSNNSPSTDNDSISK CCCCCCCCCCCCCCC	42.05	17330950
416	Phosphorylation	SPSTDNDSISKSTTE CCCCCCCCCCCCCCC	34.71	21551504
418	Phosphorylation	STDNDSISKSTTEPI CCCCCCCCCCCCCCE	25.22	25533186
419	Ubiquitination	TDNDSISKSTTEPIQ CCCCCCCCCCCCCEE	50.59	23749301
420	Phosphorylation	DNDSISKSTTEPIQL CCCCCCCCCCCCEEC	33.50	24909858
421	Phosphorylation	NDSISKSTTEPIQLN CCCCCCCCCCCEECC	38.63	28889911
422	Phosphorylation	DSISKSTTEPIQLNN CCCCCCCCCCEECCC	47.02	21551504
430	Ubiquitination	EPIQLNNKHDLHLGQ CCEECCCCCCCCCCH	37.11	22817900
438	Ubiquitination	HDLHLGQKLTESTVN CCCCCCHHCCHHHCC	56.42	17644757
440	Phosphorylation	LHLGQKLTESTVNHT CCCCHHCCHHHCCCC	34.62	19779198
442	Phosphorylation	LGQKLTESTVNHTNH CCHHCCHHHCCCCCC	32.21	17330950
443	Phosphorylation	GQKLTESTVNHTNHS CHHCCHHHCCCCCCC	21.06	17330950
447	Phosphorylation	TESTVNHTNHSDDEL CHHHCCCCCCCCCCC	29.44	19779198
450	Phosphorylation	TVNHTNHSDDELPGH HCCCCCCCCCCCCCE	49.15	28889911
471	Phosphorylation	ASRTLIRSAHHIHSA CCHHHHHHHHHHHHC	25.59	30377154
477	Phosphorylation	RSAHHIHSASSNPDI HHHHHHHHCCCCCCC	29.28	24909858
479	Phosphorylation	AHHIHSASSNPDINV HHHHHHCCCCCCCCC	33.39	19779198
480	Phosphorylation	HHIHSASSNPDINVV HHHHHCCCCCCCCCC	52.69	24909858
491	Ubiquitination	INVVDAQKRNIPINA CCCCCHHHCCCCCCE	49.48	23749301
511	Ubiquitination	FHFQDNTKTSIKVLH EEEECCCCCEEEEEE	46.67	17644757
515	Ubiquitination	DNTKTSIKVLHTPNI CCCCCEEEEEECCCH	38.21	17644757
543	Ubiquitination	DITACFTKNVLERSD CHHHHCCCCHHHCCC	25.47	17644757
559	Ubiquitination	TVLAPIVKYGDFYWV EEEEEEEECCCEEEE	44.21	17644757
568	Ubiquitination	GDFYWVSKKYLLPSN CCEEEEECEEECCCC	35.50	17644757
569	Ubiquitination	DFYWVSKKYLLPSNI CEEEEECEEECCCCC	33.36	24961812
574	Phosphorylation	SKKYLLPSNISVPTI ECEEECCCCCCCCCC	46.92	30377154
577	Phosphorylation	YLLPSNISVPTINNV EECCCCCCCCCCCCC	26.71	25521595
580	Phosphorylation	PSNISVPTINNVHTS CCCCCCCCCCCCCCC	33.89	28889911
586	Phosphorylation	PTINNVHTSESTRKY CCCCCCCCCCCCCCC	29.88	25521595
589	Phosphorylation	NNVHTSESTRKYPYP CCCCCCCCCCCCCCH	33.02	25521595
592	Ubiquitination	HTSESTRKYPYPFIH CCCCCCCCCCCHHHH	51.14	17644757
615	Ubiquitination	QTIRYSLKNNTITYF CEEEEECCCCEEEEE	42.06	15699485
644	Ubiquitination	CPDCLIGKSTKHRHI CCCCEECCCCCCCCC	48.21	15699485
657	Ubiquitination	HIKGSRLKYQNSYEP CCCCCCCCCCCCCCC	43.62	17644757
681	Ubiquitination	GPVHNLPKSAPSYFI CCCCCCCCCCCCEEE	63.52	17644757
696	Ubiquitination	SFTDETTKFRWVYPL EEECCCCCEEEEEEC	40.11	17644757
723	Ubiquitination	TTILAFIKNQFQASV HHHHHHHHHHHHCEE	37.94	15699485
748	Ubiquitination	YTNRTLHKFLEKNGI CCHHHHHHHHHHCCC	55.55	23749301
752	Ubiquitination	TLHKFLEKNGITPCY HHHHHHHHCCCCCCE	63.72	23749301
812	Phosphorylation	IVRNSLASPKSKKSA HHHHHCCCCCCHHHH	37.85	25752575
850	Ubiquitination	NDHNPNSKIHPRGIP CCCCCCCCCCCCCCC	52.23	23749301
878	Ubiquitination	IIYLPSLKKTVDTTN EEEECCCCEEECCCC	51.22	17644757
879	Ubiquitination	IYLPSLKKTVDTTNY EEECCCCEEECCCCE	60.10	17644757
880	Phosphorylation	YLPSLKKTVDTTNYV EECCCCEEECCCCEE	23.25	27017623
883	Phosphorylation	SLKKTVDTTNYVILQ CCCEEECCCCEEEEC	16.77	27017623
884	Phosphorylation	LKKTVDTTNYVILQG CCEEECCCCEEEECC	21.79	27017623
886	Phosphorylation	KTVDTTNYVILQGKE EEECCCCEEEECCCH	6.18	27017623
892	Ubiquitination	NYVILQGKESRLDQF CEEEECCCHHHHHHC	39.29	24961812
894	Phosphorylation	VILQGKESRLDQFNY EEECCCHHHHHHCCC	41.45	27017623
905	Phosphorylation	QFNYDALTFDEDLNR HCCCCCCCCCHHHHH	30.66	27017623
950	Phosphorylation	EQPRNVLSKAVSPTD CCCCCHHHHCCCCCC	17.81	17330950
951	Ubiquitination	QPRNVLSKAVSPTDS CCCCHHHHCCCCCCC	48.96	17644757
954	Phosphorylation	NVLSKAVSPTDSTPP CHHHHCCCCCCCCCC	27.26	17330950
956	Phosphorylation	LSKAVSPTDSTPPST HHHCCCCCCCCCCCC	34.77	17330950
958	Phosphorylation	KAVSPTDSTPPSTHT HCCCCCCCCCCCCCC	45.34	17330950
959	Phosphorylation	AVSPTDSTPPSTHTE CCCCCCCCCCCCCCH	41.87	17330950
962	Phosphorylation	PTDSTPPSTHTEDSK CCCCCCCCCCCHHCC	33.74	22890988
963	Phosphorylation	TDSTPPSTHTEDSKR CCCCCCCCCCHHCCC	38.29	22890988
965	Phosphorylation	STPPSTHTEDSKRVS CCCCCCCCHHCCCCC	41.39	22890988
968	Phosphorylation	PSTHTEDSKRVSKTN CCCCCHHCCCCCCCC	19.01	22890988
969	Ubiquitination	STHTEDSKRVSKTNI CCCCHHCCCCCCCCC	69.96	22817900
972	Phosphorylation	TEDSKRVSKTNIRAP CHHCCCCCCCCCCCC	37.48	21440633
973	Ubiquitination	EDSKRVSKTNIRAPR HHCCCCCCCCCCCCC	42.61	22817900
974	Phosphorylation	DSKRVSKTNIRAPRE HCCCCCCCCCCCCCC	28.50	21082442
987	Phosphorylation	REVDPNISKSDILPS CCCCCCCCHHHCCCC	32.52	28889911
988	Ubiquitination	EVDPNISKSDILPSK CCCCCCCHHHCCCCC	48.64	17644757
995	Ubiquitination	KSDILPSKKRSSTPQ HHHCCCCCCCCCCCC	50.71	17644757
996	Ubiquitination	SDILPSKKRSSTPQI HHCCCCCCCCCCCCC	62.95	17644757
998	Phosphorylation	ILPSKKRSSTPQISD CCCCCCCCCCCCCCC	47.66	28889911
999	Phosphorylation	LPSKKRSSTPQISDI CCCCCCCCCCCCCCC	48.41	17330950
1000	Phosphorylation	PSKKRSSTPQISDIE CCCCCCCCCCCCCCC	22.06	17330950
1004	Phosphorylation	RSSTPQISDIESTGS CCCCCCCCCCCCCCC	27.56	28889911
1008	Phosphorylation	PQISDIESTGSGGMH CCCCCCCCCCCCCCC	38.10	28889911
1009	Phosphorylation	QISDIESTGSGGMHR CCCCCCCCCCCCCCC	23.68	27017623
1026	Phosphorylation	VPLLAPMSQSNTHES CCEEEECCCCCCCCC	29.42	28889911
1039	Phosphorylation	ESSHTSKSKDFRHSD CCCCCCCCCCCCCCC	36.91	19779198
1045	Phosphorylation	KSKDFRHSDSYSDNE CCCCCCCCCCCCCCC	24.81	20377248
1047	Phosphorylation	KDFRHSDSYSDNETN CCCCCCCCCCCCCCC	29.56	25533186
1048	Phosphorylation	DFRHSDSYSDNETNH CCCCCCCCCCCCCCC	25.65	20377248
1049	Phosphorylation	FRHSDSYSDNETNHT CCCCCCCCCCCCCCC	37.60	17330950
1053	Phosphorylation	DSYSDNETNHTNVPI CCCCCCCCCCCCCCC	38.26	21440633
1056	Phosphorylation	SDNETNHTNVPISST CCCCCCCCCCCCCCC	39.73	17330950
1061	Phosphorylation	NHTNVPISSTGGTNN CCCCCCCCCCCCCCC	18.77	20377248
1062	Phosphorylation	HTNVPISSTGGTNNK CCCCCCCCCCCCCCC	31.62	20377248
1066	Phosphorylation	PISSTGGTNNKTVPQ CCCCCCCCCCCCCCC	36.64	28889911
1075	Phosphorylation	NKTVPQTSEQETEKR CCCCCCCCHHHHHHH	31.84	23749301
1081	Ubiquitination	TSEQETEKRIIHRSP CCHHHHHHHHHHCCC	57.21	22817900
1087	Phosphorylation	EKRIIHRSPSIDTSS HHHHHHCCCCCCCCC	14.61	17330950
1089	Phosphorylation	RIIHRSPSIDTSSSE HHHHCCCCCCCCCCC	34.05	17330950
1092	Phosphorylation	HRSPSIDTSSSESNS HCCCCCCCCCCCCCC	28.92	17287358
1093	Phosphorylation	RSPSIDTSSSESNSL CCCCCCCCCCCCCCC	28.28	28889911
1094	Phosphorylation	SPSIDTSSSESNSLH CCCCCCCCCCCCCCE	39.97	28889911
1095	Phosphorylation	PSIDTSSSESNSLHH CCCCCCCCCCCCCEE	44.82	28889911
1097	Phosphorylation	IDTSSSESNSLHHVV CCCCCCCCCCCEEEE	33.40	19779198
1099	Phosphorylation	TSSSESNSLHHVVPI CCCCCCCCCEEEEEE	38.06	28889911
1107	Ubiquitination	LHHVVPIKTSDTCPK CEEEEEEECCCCCCC	35.59	17644757
1114	Ubiquitination	KTSDTCPKENTEESI ECCCCCCCCCCCCCE	66.79	17644757
1153	Phosphorylation	PPINSRQTNSSLGGI CCCCCCCCCCCCCCC	35.64	28889911
1155	Phosphorylation	INSRQTNSSLGGIGD CCCCCCCCCCCCCCC	30.26	28889911
1156	Phosphorylation	NSRQTNSSLGGIGDS CCCCCCCCCCCCCCC	32.86	21440633
1167	Phosphorylation	IGDSNAYTTINSKKR CCCCCCCCEECCCCC	20.84	19779198
1172	Ubiquitination	AYTTINSKKRSLEDN CCCEECCCCCCCCCC	47.95	17644757
1173	Ubiquitination	YTTINSKKRSLEDNE CCEECCCCCCCCCCC	47.22	17644757
1175	Phosphorylation	TINSKKRSLEDNETE EECCCCCCCCCCCCE	45.02	17330950
1181	Phosphorylation	RSLEDNETEIKVSRD CCCCCCCCEEEEEHH	49.63	28132839
1184	Ubiquitination	EDNETEIKVSRDTWN CCCCCEEEEEHHCCC	28.11	23749301
1186	Phosphorylation	NETEIKVSRDTWNTK CCCEEEEEHHCCCCC	21.31	30377154
1193	Ubiquitination	SRDTWNTKNMRSLEP EHHCCCCCCCCCCCC	45.60	22817900
1214	Ubiquitination	IHLIAAVKAVKSIKP HHHHHHHHHHHCCCC	42.61	17644757
1236	Ubiquitination	DEAITYNKDIKEKEK CCCCCCCCCHHHHHH	50.87	23749301
1239	Ubiquitination	ITYNKDIKEKEKYIE CCCCCCHHHHHHHHH	73.24	22817900
1241	Ubiquitination	YNKDIKEKEKYIEAY CCCCHHHHHHHHHHH	55.28	22817900
1243	Ubiquitination	KDIKEKEKYIEAYHK CCHHHHHHHHHHHHH	63.70	15699485
1250	Ubiquitination	KYIEAYHKEVNQLLK HHHHHHHHHHHHHHH	51.16	15699485
1257	Ubiquitination	KEVNQLLKMKTWDTD HHHHHHHHCCCCCCC	47.12	22817900
1259	Ubiquitination	VNQLLKMKTWDTDKY HHHHHHCCCCCCCCC	44.89	22817900
1287	Ubiquitination	SMFIFNRKRDGTHKA EEEEEECCCCCCCCE	56.81	17644757
1379	Ubiquitination	KKSLYGLKQSGANWY HHHHHCCHHCCCCHH	37.75	15699485
1381	Phosphorylation	SLYGLKQSGANWYET HHHCCHHCCCCHHHH	37.98	19779198
1386	Phosphorylation	KQSGANWYETIKSYL HHCCCCHHHHHHHHH	11.73	19779198
1390	Ubiquitination	ANWYETIKSYLIEQC CCHHHHHHHHHHHCC	40.23	15699485
1434	Ubiquitination	SKDLNANKKIITTLK HCCCCCCHHHHHHHH	42.83	17644757
1435	Ubiquitination	KDLNANKKIITTLKK CCCCCCHHHHHHHHH	38.87	17644757
1441	Ubiquitination	KKIITTLKKQYDTKI HHHHHHHHHHCCCEE	35.42	17644757
1442	Ubiquitination	KIITTLKKQYDTKII HHHHHHHHHCCCEEE	58.14	17644757
1447	Ubiquitination	LKKQYDTKIINLGES HHHHCCCEEEECCCC	38.40	17644757
1468	Ubiquitination	DILGLEIKYQRSKYM HHHCEEEEECHHHHH	26.42	17644757
1502	Phosphorylation	NPKGKKLSAPGQPGL CCCCCCCCCCCCCCE	41.10	19779198
1532	Ubiquitination	EKVHEMQKLIGLASY HHHHHHHHHHHHHHH	40.54	17644757
1543	Ubiquitination	LASYVGYKFRFDLLY HHHHCCHHHHHHHHH	24.92	22106047
1598	Ubiquitination	KPTKPDNKLVAISDA CCCCCCCCEEEEEEC	52.28	17644757
1614	Ubiquitination	YGNQPYYKSQIGNIF CCCCCCEECCCCCEE	30.00	17644757
1626	Ubiquitination	NIFLLNGKVIGGKST CEEEECCEEECCCCC	29.61	17644757
1631	Ubiquitination	NGKVIGGKSTKASLT CCEEECCCCCCEEEE	50.14	17644757
1634	Ubiquitination	VIGGKSTKASLTCTS EECCCCCCEEEEECC	42.97	17644757
1669	Ubiquitination	HLVQELNKKPIIKGL HHHHHHCCCCCHHHH	72.97	17644757
1670	Ubiquitination	LVQELNKKPIIKGLL HHHHHCCCCCHHHHH	40.14	17644757
1683	Phosphorylation	LLTDSRSTISIIKST HHCCCCHHHEEEECC	20.03	21440633
1690	Phosphorylation	TISIIKSTNEEKFRN HHEEEECCCHHHHHH	41.46	27017623
1703	Ubiquitination	RNRFFGTKAMRLRDE HHHHCCCCEEEECCC	40.33	23749301
1724	Ubiquitination	YVYYIETKKNIADVM EEEEEEECCCHHHHH	30.91	17644757
1725	Ubiquitination	VYYIETKKNIADVMT EEEEEECCCHHHHHC	62.09	23749301
1732	Phosphorylation	KNIADVMTKPLPIKT CCHHHHHCCCCCCCC	29.38	20377248
1733	Ubiquitination	NIADVMTKPLPIKTF CHHHHHCCCCCCCCC	26.85	23749301
1738	Ubiquitination	MTKPLPIKTFKLLTN HCCCCCCCCCHHHHC	46.07	22817900
1741	Ubiquitination	PLPIKTFKLLTNKWI CCCCCCCHHHHCCCC	48.06	15699485

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YN12B_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YN12B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YN12B_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YN12B_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.