YLOH_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YLOH_SCHPO
• UniProt AC: Q9URY3
• Protein Name: TBC domain-containing protein C1952.17c
• Gene Name: SPAC1952.17c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 619
• Subcellular Localization: Cytoplasm .
• Protein Description: May act as a GTPase-activating protein for Rab family protein(s)..
• Protein Sequence: MDYKQRIEKFKDILNSEEPISLPGLCSLCIQGIPDEYSLRAKAWMLMLEFLPTDRSNWQSVLEKHRKTYTSFVQELLIDPWRKLTLHEESGENSDHPLNTSDDSKWKEYFDDNQILEQIDKDIRRTLPDLSFFQGKSEINKKPSVNNVSENISVNTEDDKVEEVGQKLNYTKITSIDQSQETPVHLSTIDFSKFQEECHLVLQGRIYRLENESTSSSTTALSTPRQSMDSKRTINAEAIAGENKLGLHREAAERILFIYAKLNPGIGYVQGMNEILAPLYYVLATDPTYENYYLCECDAFFLFTQMMVQVRDLYEKTLDHDSDHGIHFLMSKFTERLKKYDYELWENLEEKQIHPTYYSFRWFTCLLSQEFPLPDVIRLWDSIIADQMKARLFGKNDDGFNGAYDFLMDFCCSILIELRESILERNFADSIKLLQAHFNVDMPKLLNLTFELQHLRKTSKNDEDMSYVRKNSYNTNALANSLKNRVLSTYNTVKANVPQSSSSYTDNNKQKEPLEEKRSFFPSFRSSLDGVSPTQGRKSGEENIRTIFAKPTAHIGENGWSNLKVKGSSIFQRFGNFVGDTMRYITEEEESSEEEDLTTSRRKIGITSKRKVSVKRNVI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
85	Phosphorylation	IDPWRKLTLHEESGE HCHHHHCCCCCCCCC	29.16	29996109
90	Phosphorylation	KLTLHEESGENSDHP HCCCCCCCCCCCCCC	48.71	21712547
94	Phosphorylation	HEESGENSDHPLNTS CCCCCCCCCCCCCCC	32.75	25720772
101	Phosphorylation	SDHPLNTSDDSKWKE CCCCCCCCCCHHHHH	38.04	21712547
153	Phosphorylation	NNVSENISVNTEDDK CCCCCCEECCCCCHH	22.39	21712547
156	Phosphorylation	SENISVNTEDDKVEE CCCEECCCCCHHHHH	38.34	21712547
233	Phosphorylation	QSMDSKRTINAEAIA CCCCCCCCCCHHHHC	23.48	24763107
502	Phosphorylation	ANVPQSSSSYTDNNK CCCCCCCCCCCCCCC	32.39	25720772
504	Phosphorylation	VPQSSSSYTDNNKQK CCCCCCCCCCCCCCC	21.76	25720772
523	Phosphorylation	EKRSFFPSFRSSLDG HHHCCCHHHHHHCCC	28.30	21712547
526	Phosphorylation	SFFPSFRSSLDGVSP CCCHHHHHHCCCCCC	32.99	21712547
527	Phosphorylation	FFPSFRSSLDGVSPT CCHHHHHHCCCCCCC	26.65	25720772
532	Phosphorylation	RSSLDGVSPTQGRKS HHHCCCCCCCCCCCC	27.97	21712547
534	Phosphorylation	SLDGVSPTQGRKSGE HCCCCCCCCCCCCCH	35.83	25720772
539	Phosphorylation	SPTQGRKSGEENIRT CCCCCCCCCHHHHHH	50.50	24763107
584	Phosphorylation	FVGDTMRYITEEEES HHHHHHHHHCCCCCC	11.02	25720772
586	Phosphorylation	GDTMRYITEEEESSE HHHHHHHCCCCCCCC	28.54	25720772
591	Phosphorylation	YITEEEESSEEEDLT HHCCCCCCCCCCCCC	46.45	25720772
592	Phosphorylation	ITEEEESSEEEDLTT HCCCCCCCCCCCCCC	52.92	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YLOH_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YLOH_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YLOH_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YLOH_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.