YL12B_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YL12B_YEAST
• UniProt AC: P0C2I5
• Protein Name: Transposon Ty1-LR2 Gag-Pol polyprotein
• Gene Name: TY1B-LR2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1755
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity).; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)..
• Protein Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAPTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MESQQLSQHS -----CCCCCCCCCC	34.78	22369663
7	Phosphorylation	-MESQQLSQHSPISH -CCCCCCCCCCCCCC	22.85	22369663
10	Phosphorylation	SQQLSQHSPISHGSA CCCCCCCCCCCCHHH	19.11	22369663
13	Phosphorylation	LSQHSPISHGSACAS CCCCCCCCCHHHCCC	25.77	22369663
16	Phosphorylation	HSPISHGSACASVTS CCCCCCHHHCCCCCC	18.10	22369663
20	Phosphorylation	SHGSACASVTSKEVH CCHHHCCCCCCCCCC	26.30	22369663
22	Phosphorylation	GSACASVTSKEVHTN HHHCCCCCCCCCCCC	31.42	22369663
23	Phosphorylation	SACASVTSKEVHTNQ HHCCCCCCCCCCCCC	25.35	22369663
24	Ubiquitination	ACASVTSKEVHTNQD HCCCCCCCCCCCCCC	55.16	24961812
28	Phosphorylation	VTSKEVHTNQDPLDV CCCCCCCCCCCCCCC	39.49	21440633
36	Phosphorylation	NQDPLDVSASKTEEC CCCCCCCCCCCHHHH	26.88	25533186
38	Phosphorylation	DPLDVSASKTEECEK CCCCCCCCCHHHHHH	32.38	17330950
39	Ubiquitination	PLDVSASKTEECEKA CCCCCCCCHHHHHHH	60.72	23749301
40	Phosphorylation	LDVSASKTEECEKAS CCCCCCCHHHHHHHH	34.22	21440633
45	Ubiquitination	SKTEECEKASTKANS CCHHHHHHHHCCCCC	60.33	17644757
47	Phosphorylation	TEECEKASTKANSQQ HHHHHHHHCCCCCCC	41.32	17330950
48	Phosphorylation	EECEKASTKANSQQT HHHHHHHCCCCCCCC	38.75	25005228
71	Phosphorylation	PENPHHASPQPASVP CCCCCCCCCCCCCCC	21.51	28889911
145	Phosphorylation	GTPLSTPSPESGNTF CCCCCCCCCCCCCCC	41.19	28889911
157	Phosphorylation	NTFTDSSSADSDMTS CCCCCCCCCCCCCCC	39.79	28889911
160	Phosphorylation	TDSSSADSDMTSTKK CCCCCCCCCCCCCCC	29.06	16445868
166	Ubiquitination	DSDMTSTKKYVRPPP CCCCCCCCCCCCCCC	41.70	15699485
167	Ubiquitination	SDMTSTKKYVRPPPM CCCCCCCCCCCCCCC	49.41	17644757
176	Phosphorylation	VRPPPMLTSPNDFPN CCCCCCCCCCCCCCH	35.57	17330950
177	Phosphorylation	RPPPMLTSPNDFPNW CCCCCCCCCCCCCHH	20.11	17330950
186	Ubiquitination	NDFPNWVKTYIKFLQ CCCCHHHHHHHHHHH	27.50	17644757
190	Ubiquitination	NWVKTYIKFLQNSNL HHHHHHHHHHHCCCC	29.61	17644757
203	Phosphorylation	NLGGIIPTVNGKPVR CCCCEEECCCCEECE	19.05	24909858
207	Ubiquitination	IIPTVNGKPVRQITD EEECCCCEECEECCH	34.83	23749301
238	Ubiquitination	QFLPTWVKDILSVDY HCCCHHHHHHHCCCH	30.52	15699485
250	Ubiquitination	VDYTDIMKILSKSIE CCHHHHHHHHHHHHH	40.61	24961812
255	Phosphorylation	IMKILSKSIEKMQSD HHHHHHHHHHHHHHC	32.38	21440633
261	Phosphorylation	KSIEKMQSDTQEAND HHHHHHHHCCHHHHH	38.84	28132839
263	Phosphorylation	IEKMQSDTQEANDIV HHHHHHCCHHHHHHH	33.29	28132839
280	Phosphorylation	ANLQYNGSTPADAFE HHCEECCCCHHHHHH	27.81	28889911
281	Phosphorylation	NLQYNGSTPADAFET HCEECCCCHHHHHHH	24.72	27214570
289	Ubiquitination	PADAFETKVTNIIDR HHHHHHHHHHHHHHH	39.60	17644757
307	Ubiquitination	NGIHINNKVACQLIM CCCCCCCHHHHHHHH	27.07	17644757
318	Phosphorylation	QLIMRGLSGEYKFLR HHHHCCCCCCHHHHH	32.19	21440633
322	Ubiquitination	RGLSGEYKFLRYTRH CCCCCCHHHHHHHCH	33.35	23749301
353	Phosphorylation	IYEEQQGSRNSKPNY HHHHHCCCCCCCCCC	24.77	28889911
357	Ubiquitination	QQGSRNSKPNYRRNL HCCCCCCCCCCCCCC	40.61	22817900
365	Phosphorylation	PNYRRNLSDEKNDSR CCCCCCCCCCCCCCC	47.47	21082442
368	Ubiquitination	RRNLSDEKNDSRSYT CCCCCCCCCCCCCCC	71.67	23749301
371	Phosphorylation	LSDEKNDSRSYTNTT CCCCCCCCCCCCCCC	32.30	17287358
373	Phosphorylation	DEKNDSRSYTNTTKP CCCCCCCCCCCCCCC	40.02	22890988
374	Phosphorylation	EKNDSRSYTNTTKPK CCCCCCCCCCCCCCE	11.69	22890988
375	Phosphorylation	KNDSRSYTNTTKPKV CCCCCCCCCCCCCEE	27.60	21551504
377	Phosphorylation	DSRSYTNTTKPKVIA CCCCCCCCCCCEEEE	28.53	22890988
378	Phosphorylation	SRSYTNTTKPKVIAR CCCCCCCCCCEEEEC	47.63	22890988
379	Ubiquitination	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	22817900
381	Ubiquitination	YTNTTKPKVIARNPQ CCCCCCCEEEECCCC	48.07	22817900
397	Phosphorylation	TNNSKSKTARAHNVS CCCCCCCCCHHCCCC	28.59	21551504
404	Phosphorylation	TARAHNVSTSNNSPS CCHHCCCCCCCCCCC	31.28	25533186
405	Phosphorylation	ARAHNVSTSNNSPST CHHCCCCCCCCCCCC	31.06	25533186
406	Phosphorylation	RAHNVSTSNNSPSTD HHCCCCCCCCCCCCC	26.89	21551504
409	Phosphorylation	NVSTSNNSPSTDNDS CCCCCCCCCCCCCCC	25.20	17330950
411	Phosphorylation	STSNNSPSTDNDSIS CCCCCCCCCCCCCCC	48.49	17330950
412	Phosphorylation	TSNNSPSTDNDSISK CCCCCCCCCCCCCCC	42.05	17330950
416	Phosphorylation	SPSTDNDSISKSTTE CCCCCCCCCCCCCCC	34.71	21551504
418	Phosphorylation	STDNDSISKSTTEPI CCCCCCCCCCCCCCE	25.22	25533186
419	Ubiquitination	TDNDSISKSTTEPIQ CCCCCCCCCCCCCEE	50.59	23749301
420	Phosphorylation	DNDSISKSTTEPIQL CCCCCCCCCCCCEEC	33.50	24909858
421	Phosphorylation	NDSISKSTTEPIQLN CCCCCCCCCCCEECC	38.63	28889911
422	Phosphorylation	DSISKSTTEPIQLNN CCCCCCCCCCEECCC	47.02	21551504
430	Ubiquitination	EPIQLNNKHDLHLGQ CCEECCCCCCCCCCH	37.11	22817900
440	Phosphorylation	LHLGQELTESTVNHT CCCCHHHHHHHCCCC	27.43	19779198
442	Phosphorylation	LGQELTESTVNHTNH CCHHHHHHHCCCCCC	32.21	29688323
443	Phosphorylation	GQELTESTVNHTNHS CHHHHHHHCCCCCCC	21.06	17330950
447	Phosphorylation	TESTVNHTNHSDDEL HHHHCCCCCCCCCCC	29.44	19779198
450	Phosphorylation	TVNHTNHSDDELPGH HCCCCCCCCCCCCCE	49.15	28889911
471	Phosphorylation	ASRTLIRSAHHIHSA CCHHHHHHHHHHHHC	25.59	30377154
477	Phosphorylation	RSAHHIHSASSNPDI HHHHHHHHCCCCCCC	29.28	24909858
479	Phosphorylation	AHHIHSASSNPDINV HHHHHHCCCCCCCCC	33.39	19779198
480	Phosphorylation	HHIHSASSNPDINVV HHHHHCCCCCCCCCC	52.69	24909858
491	Ubiquitination	INVVDAQKRNIPINA CCCCCHHHCCCCCCE	49.48	23749301
511	Ubiquitination	FHFQDNTKTSIKVLH EEEECCCCCEEEEEE	46.67	17644757
515	Ubiquitination	DNTKTSIKVLHTPNI CCCCCEEEEEECCCH	38.21	17644757
543	Ubiquitination	DITACFTKNVLERSD CHHHHCCCCHHHCCC	25.47	17644757
559	Ubiquitination	TVLAPIVKYGDFYWV EEEEEEEECCCEEEE	44.21	17644757
568	Ubiquitination	GDFYWVSKKYLLPSN CCEEEEECEEECCCC	35.50	17644757
569	Ubiquitination	DFYWVSKKYLLPSNI CEEEEECEEECCCCC	33.36	24961812
574	Phosphorylation	SKKYLLPSNISVPTI ECEEECCCCCCCCCC	46.92	30377154
577	Phosphorylation	YLLPSNISVPTINNV EECCCCCCCCCCCCC	26.71	25521595
580	Phosphorylation	PSNISVPTINNVHTS CCCCCCCCCCCCCCC	33.89	28889911
586	Phosphorylation	PTINNVHTSESTRKY CCCCCCCCCCCCCCC	29.88	25521595
589	Phosphorylation	NNVHTSESTRKYPYP CCCCCCCCCCCCCCH	33.02	25521595
592	Ubiquitination	HTSESTRKYPYPFIH CCCCCCCCCCCHHHH	51.14	17644757
615	Ubiquitination	PTIRYSLKNNTITYF CEEEEECCCCEEEEE	42.06	15699485
644	Ubiquitination	CPDCLIGKSTKHRHI CCCCEECCCCCCCCC	48.21	15699485
696	Ubiquitination	SFTDETTKFRWVYPL EEECCCCCEEEEEEC	40.11	17644757
723	Ubiquitination	TTILAFIKNQFQASV HHHHHHHHHHHHCEE	37.94	15699485
748	Ubiquitination	YTNRTLHKFLEKNGI CCHHHHHHHHHHCCC	55.55	23749301
752	Ubiquitination	TLHKFLEKNGITPCY HHHHHHHHCCCCCCE	63.72	23749301
812	Phosphorylation	IVRNSLASPKSKKSA HHHHHCCCCCCHHHH	37.85	25752575
850	Ubiquitination	NDHNPNSKIHPRGIP CCCCCCCCCCCCCCC	52.23	23749301
878	Ubiquitination	IIYLPSLKKTVDTTN EEEECCCCEEECCCC	51.22	17644757
879	Ubiquitination	IYLPSLKKTVDTTNY EEECCCCEEECCCCE	60.10	17644757
880	Phosphorylation	YLPSLKKTVDTTNYV EECCCCEEECCCCEE	23.25	27017623
883	Phosphorylation	SLKKTVDTTNYVILQ CCCEEECCCCEEEEC	16.77	27017623
884	Phosphorylation	LKKTVDTTNYVILQG CCEEECCCCEEEECC	21.79	27017623
886	Phosphorylation	KTVDTTNYVILQGKE EEECCCCEEEECCCH	6.18	27017623
892	Ubiquitination	NYVILQGKESRLDQF CEEEECCCHHHHHHC	39.29	24961812
894	Phosphorylation	VILQGKESRLDQFNY EEECCCHHHHHHCCC	41.45	27017623
905	Phosphorylation	QFNYDALTFDEDLNR HCCCCCCCCCHHHHH	30.66	27017623
914	Phosphorylation	DEDLNRLTASYHSFI CHHHHHHHHHHHHHH	15.43	19779198
936	Phosphorylation	SNDLNIESDHDFQSD CCCCCCCCCCCHHHC	36.13	28889911
942	Phosphorylation	ESDHDFQSDIELHPE CCCCCHHHCCCCCCC	40.32	28889911
956	Phosphorylation	EQPRNVLSKAVSPTD CCCCCHHHHCCCCCC	17.81	17330950
957	Ubiquitination	QPRNVLSKAVSPTDS CCCCHHHHCCCCCCC	48.96	17644757
960	Phosphorylation	NVLSKAVSPTDSTPP CHHHHCCCCCCCCCC	27.26	17330950
962	Phosphorylation	LSKAVSPTDSTPPST HHHCCCCCCCCCCCC	34.77	17330950
964	Phosphorylation	KAVSPTDSTPPSTHT HCCCCCCCCCCCCCC	45.34	17330950
965	Phosphorylation	AVSPTDSTPPSTHTE CCCCCCCCCCCCCCH	41.87	17330950
968	Phosphorylation	PTDSTPPSTHTEDSK CCCCCCCCCCCHHCC	33.74	22890988
969	Phosphorylation	TDSTPPSTHTEDSKR CCCCCCCCCCHHCCC	38.29	22890988
971	Phosphorylation	STPPSTHTEDSKRVS CCCCCCCCHHCCCCC	41.39	22890988
974	Phosphorylation	PSTHTEDSKRVSKTN CCCCCHHCCCCCCCC	19.01	22890988
975	Ubiquitination	STHTEDSKRVSKTNI CCCCHHCCCCCCCCC	69.96	22817900
978	Phosphorylation	TEDSKRVSKTNIRAP CHHCCCCCCCCCCCC	37.48	21440633
979	Ubiquitination	EDSKRVSKTNIRAPR HHCCCCCCCCCCCCC	42.61	22817900
980	Phosphorylation	DSKRVSKTNIRAPRE HCCCCCCCCCCCCCC	28.50	28889911
993	Phosphorylation	REVDPNISESNILPS CCCCCCCCHHHCCCC	41.43	25533186
995	Phosphorylation	VDPNISESNILPSKK CCCCCCHHHCCCCCC	23.52	22890988
1000	Phosphorylation	SESNILPSKKRSSTP CHHHCCCCCCCCCCC	47.57	22890988
1001	Ubiquitination	ESNILPSKKRSSTPQ HHHCCCCCCCCCCCC	50.71	17644757
1002	Ubiquitination	SNILPSKKRSSTPQI HHCCCCCCCCCCCCC	62.95	17644757
1004	Phosphorylation	ILPSKKRSSTPQISN CCCCCCCCCCCCCCC	47.66	17330950
1005	Phosphorylation	LPSKKRSSTPQISNI CCCCCCCCCCCCCCC	48.41	17330950
1006	Phosphorylation	PSKKRSSTPQISNIE CCCCCCCCCCCCCCE	22.06	17330950
1010	Phosphorylation	RSSTPQISNIESTGS CCCCCCCCCCEECCC	26.89	22890988
1014	Phosphorylation	PQISNIESTGSGGMH CCCCCCEECCCCCCC	33.98	22890988
1015	Phosphorylation	QISNIESTGSGGMHK CCCCCEECCCCCCCC	23.68	22890988
1017	Phosphorylation	SNIESTGSGGMHKLN CCCEECCCCCCCCCC	32.06	22890988
1022	Ubiquitination	TGSGGMHKLNVPLLA CCCCCCCCCCCCEEE	32.63	17644757
1032	Phosphorylation	VPLLAPMSQSNTHES CCEEEECCCCCCCCC	29.42	28889911
1034	Phosphorylation	LLAPMSQSNTHESSH EEEECCCCCCCCCCC	36.07	19779198
1036	Phosphorylation	APMSQSNTHESSHAS EECCCCCCCCCCCCC	32.06	28889911
1039	Phosphorylation	SQSNTHESSHASKSK CCCCCCCCCCCCCCC	21.59	21440633
1043	Phosphorylation	THESSHASKSKDFRH CCCCCCCCCCCCCCC	31.85	28889911
1044	Ubiquitination	HESSHASKSKDFRHS CCCCCCCCCCCCCCC	63.41	17644757
1045	Phosphorylation	ESSHASKSKDFRHSD CCCCCCCCCCCCCCC	34.66	28889911
1046	Ubiquitination	SSHASKSKDFRHSDS CCCCCCCCCCCCCCC	65.70	15699485
1051	Phosphorylation	KSKDFRHSDSYSENE CCCCCCCCCCCCCCC	24.81	17330950
1053	Phosphorylation	KDFRHSDSYSENETN CCCCCCCCCCCCCCC	33.31	17330950
1054	Phosphorylation	DFRHSDSYSENETNH CCCCCCCCCCCCCCC	25.62	17330950
1055	Phosphorylation	FRHSDSYSENETNHT CCCCCCCCCCCCCCC	37.59	17330950
1059	Phosphorylation	DSYSENETNHTNVPI CCCCCCCCCCCCCCC	43.83	17330950
1062	Phosphorylation	SENETNHTNVPISST CCCCCCCCCCCCCCC	39.73	22890988
1067	Phosphorylation	NHTNVPISSTGGTNN CCCCCCCCCCCCCCC	18.77	22890988
1068	Phosphorylation	HTNVPISSTGGTNNK CCCCCCCCCCCCCCC	31.62	22890988
1069	Phosphorylation	TNVPISSTGGTNNKT CCCCCCCCCCCCCCC	32.60	22890988
1072	Phosphorylation	PISSTGGTNNKTVPQ CCCCCCCCCCCCCCC	36.64	22890988
1075	Ubiquitination	STGGTNNKTVPQISD CCCCCCCCCCCCCCC	53.63	17644757
1076	Phosphorylation	TGGTNNKTVPQISDQ CCCCCCCCCCCCCCH	39.27	28132839
1081	Phosphorylation	NKTVPQISDQETEKR CCCCCCCCCHHHHHH	28.17	17330950
1085	Phosphorylation	PQISDQETEKRIIHR CCCCCHHHHHHHHCC	40.97	22890988
1087	Ubiquitination	ISDQETEKRIIHRSP CCCHHHHHHHHCCCC	57.21	22817900
1093	Phosphorylation	EKRIIHRSPSIDASP HHHHHCCCCCCCCCC	14.61	17330950
1095	Phosphorylation	RIIHRSPSIDASPPE HHHCCCCCCCCCCCC	34.05	17330950
1099	Phosphorylation	RSPSIDASPPENNSS CCCCCCCCCCCCCCC	36.92	21551504
1105	Phosphorylation	ASPPENNSSHNIVPI CCCCCCCCCCCEEEC	44.55	21551504
1106	Phosphorylation	SPPENNSSHNIVPIK CCCCCCCCCCEEECC	23.76	22890988
1113	Ubiquitination	SHNIVPIKTPTTVSE CCCEEECCCCCCCCC	42.24	15699485
1140	Phosphorylation	LPDLPPESPTEFPDP CCCCCCCCCCCCCCC	42.78	23607784
1142	Phosphorylation	DLPPESPTEFPDPFK CCCCCCCCCCCCCCC	60.58	21440633
1159	Phosphorylation	PPINSRQTNSSLGGI CCCCCCCCCCCCCCC	35.64	28889911
1161	Phosphorylation	INSRQTNSSLGGIGD CCCCCCCCCCCCCCC	30.26	28889911
1162	Phosphorylation	NSRQTNSSLGGIGDS CCCCCCCCCCCCCCC	32.86	21440633
1173	Phosphorylation	IGDSNAYTTINSKKR CCCCCCCCEECCCCC	20.84	19779198
1178	Ubiquitination	AYTTINSKKRSLEDN CCCEECCCCCCCCCC	47.95	17644757
1179	Ubiquitination	YTTINSKKRSLEDNE CCEECCCCCCCCCCC	47.22	17644757
1181	Phosphorylation	TINSKKRSLEDNETE EECCCCCCCCCCCCE	45.02	17330950
1187	Phosphorylation	RSLEDNETEIKVSRD CCCCCCCCEEEEEHH	49.63	28132839
1190	Ubiquitination	EDNETEIKVSRDTWN CCCCCEEEEEHHCCC	28.11	23749301
1192	Phosphorylation	NETEIKVSRDTWNTK CCCEEEEEHHCCCCC	21.31	30377154
1199	Ubiquitination	SRDTWNTKNMRSLEP EHHCCCCCCCCCCCC	45.60	22817900
1220	Ubiquitination	IHLIAAVKAVKSIKP HHHHHHHHHHHCCCC	42.61	17644757
1242	Ubiquitination	DEAITYNKDIKEKEK CCCCCCCCCHHHHHH	50.87	23749301
1245	Ubiquitination	ITYNKDIKEKEKYIE CCCCCCHHHHHHHHH	73.24	22817900
1247	Ubiquitination	YNKDIKEKEKYIEAY CCCCHHHHHHHHHHH	55.28	22817900
1249	Ubiquitination	KDIKEKEKYIEAYHK CCHHHHHHHHHHHHH	63.70	15699485
1256	Ubiquitination	KYIEAYHKEVNQLLK HHHHHHHHHHHHHHH	51.16	15699485
1263	Ubiquitination	KEVNQLLKMKTWDTD HHHHHHHHCCCCCCC	47.12	22817900
1265	Ubiquitination	VNQLLKMKTWDTDEY HHHHHHCCCCCCCCC	44.89	22817900
1266	Phosphorylation	NQLLKMKTWDTDEYY HHHHHCCCCCCCCCC	25.69	28889911
1276	Ubiquitination	TDEYYDRKEIDPKRV CCCCCCCCCCCHHHH	57.00	15699485
1281	Ubiquitination	DRKEIDPKRVINSMF CCCCCCHHHHHEEEE	56.39	15699485
1292	Ubiquitination	NSMFIFNKKRDGTHK EEEEEEECCCCCCCC	38.14	17644757
1293	Ubiquitination	SMFIFNKKRDGTHKA EEEEEECCCCCCCCE	57.75	17644757
1385	Ubiquitination	KKSLYGLKQSGANWY HHHHHCCHHCCCCHH	37.75	15699485
1387	Phosphorylation	SLYGLKQSGANWYET HHHCCHHCCCCHHHH	37.98	19779198
1392	Phosphorylation	KQSGANWYETIKSYL HHCCCCHHHHHHHHH	11.73	19779198
1396	Ubiquitination	ANWYETIKSYLIKQC CCHHHHHHHHHHHHH	40.23	15699485
1401	Ubiquitination	TIKSYLIKQCGMEEV HHHHHHHHHHCCHHH	36.62	24961812
1440	Ubiquitination	SKDLNANKKIITTLK HCCCCCCHHHHHHHH	42.83	17644757
1441	Ubiquitination	KDLNANKKIITTLKK CCCCCCHHHHHHHHH	38.87	17644757
1447	Ubiquitination	KKIITTLKKQYDTKI HHHHHHHHHHCCCEE	35.42	17644757
1448	Ubiquitination	KIITTLKKQYDTKII HHHHHHHHHCCCEEE	58.14	17644757
1453	Ubiquitination	LKKQYDTKIINLGES HHHHCCCEEEECCCC	38.40	17644757
1474	Ubiquitination	DILGLEIKYQRGKYM EEECEEEEEECCCCC	26.42	17644757
1480	Phosphorylation	IKYQRGKYMKLGMEN EEEECCCCCCCCCCC	11.42	19779198
1482	Ubiquitination	YQRGKYMKLGMENSL EECCCCCCCCCCCCC	38.51	15699485
1492	Ubiquitination	MENSLTEKIPKLNVP CCCCCCCCCCCCCCC	60.10	23749301
1495	Ubiquitination	SLTEKIPKLNVPLNP CCCCCCCCCCCCCCC	57.05	22817900
1503	Ubiquitination	LNVPLNPKGRKLSAP CCCCCCCCCCCCCCC	70.99	22817900
1506	Ubiquitination	PLNPKGRKLSAPGQP CCCCCCCCCCCCCCC	56.30	22817900
1508	Phosphorylation	NPKGRKLSAPGQPGL CCCCCCCCCCCCCCE	35.14	28889911
1538	Ubiquitination	EKVHEMQKLIGLASY HHHHHHHHHHHHHHH	40.54	17644757
1549	Ubiquitination	LASYVGYKFRFDLLY HHHHCCHHHHHHHHH	24.92	22106047
1595	Ubiquitination	DKQLIWHKNKPTEPD CCEEEEECCCCCCCC	52.23	15699485
1597	Ubiquitination	QLIWHKNKPTEPDNK EEEEECCCCCCCCCC	59.11	15699485
1604	Ubiquitination	KPTEPDNKLVAISDA CCCCCCCCEEEEEEC	52.28	24961812
1620	Ubiquitination	YGNQPYYKSQIGNIY CCCCCCEECCCCCEE	30.00	17644757
1632	Ubiquitination	NIYLLNGKVIGGKST CEEEECCEEECCCCC	29.61	17644757
1640	Ubiquitination	VIGGKSTKASLTCTS EECCCCCCEEEEECC	42.97	15699485
1642	Phosphorylation	GGKSTKASLTCTSTT CCCCCCEEEEECCCC	26.26	30377154
1644	Phosphorylation	KSTKASLTCTSTTEA CCCCEEEEECCCCHH	15.96	30377154
1646	Phosphorylation	TKASLTCTSTTEAEI CCEEEEECCCCHHHH	24.71	30377154
1647	Phosphorylation	KASLTCTSTTEAEIH CEEEEECCCCHHHHH	35.16	30377154
1657	Phosphorylation	EAEIHAISESVPLLN HHHHHHHHHCCHHHH	25.30	30377154
1659	Phosphorylation	EIHAISESVPLLNNL HHHHHHHCCHHHHHH	23.42	30377154
1675	Ubiquitination	YLIQELNKKPIIKGL HHHHHHHCCCCHHHH	72.97	15699485
1676	Ubiquitination	LIQELNKKPIIKGLL HHHHHHCCCCHHHHH	40.14	15699485
1689	Phosphorylation	LLTDSRSTISIIKST HHCCCCHHHEEEECC	20.03	21440633
1696	Phosphorylation	TISIIKSTNEEKFRN HHEEEECCCHHHHHH	41.46	27017623
1709	Ubiquitination	RNRFFGTKAMRLRDE HHHHCCCCEEEECCC	40.33	23749301
1730	Ubiquitination	YVYYIETKKNIADVM EEEEEEECCCHHHHH	30.91	17644757
1731	Ubiquitination	VYYIETKKNIADVMT EEEEEECCCHHHHHC	62.09	23749301
1738	Phosphorylation	KNIADVMTKPLPIKT CCHHHHHCCCCCCCC	29.38	20377248
1739	Ubiquitination	NIADVMTKPLPIKTF CHHHHHCCCCCCCCC	26.85	23749301
1744	Ubiquitination	MTKPLPIKTFKLLTN HCCCCCCCCCHHHHC	46.07	22817900
1747	Ubiquitination	PLPIKTFKLLTNKWI CCCCCCCHHHHCCCC	48.06	15699485

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YL12B_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YL12B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YL12B_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YL12B_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.