dbPTM

YKV5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YKV5_SCHPO
UniProt AC	Q9P4X1
Protein Name	Thioredoxin domain-containing protein C959.05c
Gene Name	SPAC959.05c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	632
Subcellular Localization	Endoplasmic reticulum membrane Single-pass membrane protein .
Protein Description	Acts as a membrane-bound chaperone in endoplasmic reticulum quality control. Probably facilitates presentation of substrate to membrane-bound components of the degradation machinery (By similarity)..
Protein Sequence	MKLFLYHFTFIVYYFIISFSYAFSIKQEIIVSSHNASSILNTTAFWFVEFTESKYDKEEFSVIWNEVSMEFPDIRRAKVFCDLDLEFCAQQEIYDHPKVVVLKNGMWMRHVLEKNQITTKSARQFVKSHLGNCDLEQAENETDCFSDDGEYNSDSSSTDPAFELKEDQSWKHSSILRPLETLNFKRFLFGNEIMSKTRAFVMFVSLKHCEDCFHWEAVWSSITRNTDERLKMAQVNCDEEKEMCNHFHIKKFPTFRVFQGFDSIQYNGPLKYQQLLSYSNQVASYQAIKIEEGDIESIENSHPVFFLVLYDFATTSEDFSIIERLKLQLAGVAPLYICNSKALANKYGAQSQPSIIAVRNGMPIVYQAITPREFRDYKRITEWINIVSSPFITELTPTKCHSLLNRKLTVLTLLQPDSEQFFSSQEELLRLGKRWFRFQMQRQRNDIVWSRIKKYSAIAEAKKKGFARKVKRIKYSKISHPTYTESVSFLWLDSSLWLDWIVENLDHTVYVDSITPPVFVIDHSKGVIYVSDRNGNSLTLEEDSLFSTLRIILEHPNSSRLQKLRAPGLCPNGSPNYRNRYKLIVFNLLIALLILSILTIISASRLSRRRRQLLNKQPVFGFYHSLVIAKSD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	N-linked_Glycosylation	EIIVSSHNASSILNT EEEEECCCHHHHHHH	43.39	-
41	N-linked_Glycosylation	HNASSILNTTAFWFV CCHHHHHHHCEEEEE	33.44	-
140	N-linked_Glycosylation	CDLEQAENETDCFSD CCHHHHCCCCCCCCC	61.56	-
557	N-linked_Glycosylation	RIILEHPNSSRLQKL HHHHHCCCCHHHHHH	55.30	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YKV5_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YKV5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YKV5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YKV5_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YKV5_SCHPO

Related Literatures of Post-Translational Modification