YJX4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YJX4_SCHPO
• UniProt AC: Q9UU99
• Protein Name: CRAL-TRIO domain-containing protein C23B6.04c
• Gene Name: SPCC23B6.04c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1008
• Subcellular Localization: Cell membrane ; Peripheral membrane protein . Cell periphery.
• Protein Sequence: MKDSEHHHHGHNGFSKFLHKLGFGKSKGKSHKSNTSSIHERENTAAKGPASNVRPARPNVSTSSTSNEVRKSVPVGNPTVHTKTGSSSSPASKMRNTVNLQHIQAANQKTRNAEGERKVAQRRVQSDKAEANDAAMSSSAPTVDVSEGNSAAEPKITPDDSDTPRLNVDMNDKINVDEAAAKSDSKLNVDQINSTTESEKRVEKVNPNIANNPLKSPDAVAYSSETVSDEKQPTEHPVSANVPAKSEKAVCDENTKISLTNTEHYKFHSLRGDVEVVVGDLERDGRDTSLGDASVNEAAKETDVDSSRFISDEKAVTEDAMKTEHASNAPLTDERHFQFHSSEGDIEGIVGTMQRQRQSVSSYDTIVPSQFYKQKVVQNSPPSLLSTDNKIPESGSDHPSSQDNSSKASLVENSQTQSSTPRKPLPTTTSPKVNPEPHSESISDTRPSTPRKVPPSTVPKMNPKLQGGNSVTAPSTPSKVLPAMSPKVAPKFQGGRSSTAPSTPNKVLPAASAKAAPKLQEKAASFDIPNKSTIISTKSTVASPIKANENSPALKSKASFEFPKELDPDGTWNAPIPYPDANCPMAPTYRNLTSEQEEMYEEVLKYCLELKEIPVASNSSKKTDLIELERLWLTRECILRYLRATKWHVSNAKKRIVDTLVWRRHFGVNNMDPDEIQEENATGKQVLLGYDKDGRPCLYLYPARQNTKTSPLQIRHLVFSLECAIDLMPPGVETLALLINFKSSSNRSNPSVGQGKEVLNILQTHYCERLGRALVINIPWAVWGFFKLISPFIDPITREKLKFNEPLDRYVPKDQLDSNFGGSLHFEYHHEKYWPQLVELCKSRRLGILEKWRKMGSKIGTSEWDLKGGEEYVELMQQYVRPSLTNRSSSPTVTPTVNTDRQPKTLTNSADELSPQKRRVENPKPVVKDEGPVSIVEDEESTPVVTKKEDSIPVAQSTKADAGLDAENDLLPKSGSGVSETPAFSHARDVSTASFSDAVSFITADSIE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	SKGKSHKSNTSSIHE CCCCCCCCCCHHHHH	39.66	21712547
35	Phosphorylation	GKSHKSNTSSIHERE CCCCCCCCHHHHHHH	30.83	21712547
36	Phosphorylation	KSHKSNTSSIHEREN CCCCCCCHHHHHHHC	31.39	25720772
37	Phosphorylation	SHKSNTSSIHERENT CCCCCCHHHHHHHCC	26.40	21712547
44	Phosphorylation	SIHERENTAAKGPAS HHHHHHCCCCCCCHH	24.20	24763107
61	Phosphorylation	RPARPNVSTSSTSNE CCCCCCCCCCCCCCC	29.25	25720772
62	Phosphorylation	PARPNVSTSSTSNEV CCCCCCCCCCCCCCH	23.55	25720772
63	Phosphorylation	ARPNVSTSSTSNEVR CCCCCCCCCCCCCHH	24.90	25720772
64	Phosphorylation	RPNVSTSSTSNEVRK CCCCCCCCCCCCHHH	35.62	25720772
65	Phosphorylation	PNVSTSSTSNEVRKS CCCCCCCCCCCHHHC	35.03	25720772
72	Phosphorylation	TSNEVRKSVPVGNPT CCCCHHHCCCCCCCE	22.53	24763107
146	Phosphorylation	SAPTVDVSEGNSAAE CCCEEECCCCCCCCC	35.01	29996109
150	Phosphorylation	VDVSEGNSAAEPKIT EECCCCCCCCCCCCC	39.45	29996109
183	Phosphorylation	VDEAAAKSDSKLNVD HHHHHHHCCCCCCHH	42.25	28889911
185	Phosphorylation	EAAAKSDSKLNVDQI HHHHHCCCCCCHHHH	46.24	28889911
198	Phosphorylation	QINSTTESEKRVEKV HHCCCHHHHHHHHHC	46.45	29996109
246	Phosphorylation	SANVPAKSEKAVCDE CCCCCCCCCCCCCCC	46.57	21712547
258	Phosphorylation	CDENTKISLTNTEHY CCCCCCEEECCCCCE	30.60	21712547
262	Phosphorylation	TKISLTNTEHYKFHS CCEEECCCCCEEEEC	20.92	21712547
288	Phosphorylation	LERDGRDTSLGDASV CEECCCCCCCCCCCH	25.21	21712547
289	Phosphorylation	ERDGRDTSLGDASVN EECCCCCCCCCCCHH	34.34	28889911
294	Phosphorylation	DTSLGDASVNEAAKE CCCCCCCCHHHHHHH	30.16	29996109
302	Phosphorylation	VNEAAKETDVDSSRF HHHHHHHCCCCHHHC	40.39	25720772
306	Phosphorylation	AKETDVDSSRFISDE HHHCCCCHHHCCCCH	24.22	24763107
307	Phosphorylation	KETDVDSSRFISDEK HHCCCCHHHCCCCHH	27.09	21712547
311	Phosphorylation	VDSSRFISDEKAVTE CCHHHCCCCHHHCCH	36.68	29996109
359	Phosphorylation	TMQRQRQSVSSYDTI HHHHHHCCCCCCCCC	26.59	25720772
361	Phosphorylation	QRQRQSVSSYDTIVP HHHHCCCCCCCCCCC	28.55	25720772
362	Phosphorylation	RQRQSVSSYDTIVPS HHHCCCCCCCCCCCH	25.52	25720772
363	Phosphorylation	QRQSVSSYDTIVPSQ HHCCCCCCCCCCCHH	15.03	25720772
365	Phosphorylation	QSVSSYDTIVPSQFY CCCCCCCCCCCHHHH	18.68	25720772
380	Phosphorylation	KQKVVQNSPPSLLST HHHHHCCCCCHHHCC	22.54	24763107
383	Phosphorylation	VVQNSPPSLLSTDNK HHCCCCCHHHCCCCC	45.38	28889911
386	Phosphorylation	NSPPSLLSTDNKIPE CCCCHHHCCCCCCCC	38.72	25720772
387	Phosphorylation	SPPSLLSTDNKIPES CCCHHHCCCCCCCCC	43.49	21712547
394	Phosphorylation	TDNKIPESGSDHPSS CCCCCCCCCCCCCCC	37.94	29996109
396	Phosphorylation	NKIPESGSDHPSSQD CCCCCCCCCCCCCCC	41.86	29996109
400	Phosphorylation	ESGSDHPSSQDNSSK CCCCCCCCCCCCCCC	36.89	28889911
401	Phosphorylation	SGSDHPSSQDNSSKA CCCCCCCCCCCCCCH	46.10	21712547
405	Phosphorylation	HPSSQDNSSKASLVE CCCCCCCCCCHHHHC	41.32	28889911
406	Phosphorylation	PSSQDNSSKASLVEN CCCCCCCCCHHHHCC	38.20	21712547
409	Phosphorylation	QDNSSKASLVENSQT CCCCCCHHHHCCCCC	36.36	21712547
414	Phosphorylation	KASLVENSQTQSSTP CHHHHCCCCCCCCCC	22.54	21712547
416	Phosphorylation	SLVENSQTQSSTPRK HHHCCCCCCCCCCCC	30.18	21712547
418	Phosphorylation	VENSQTQSSTPRKPL HCCCCCCCCCCCCCC	39.30	21712547
419	Phosphorylation	ENSQTQSSTPRKPLP CCCCCCCCCCCCCCC	32.39	29996109
420	Phosphorylation	NSQTQSSTPRKPLPT CCCCCCCCCCCCCCC	32.15	21712547
428	Phosphorylation	PRKPLPTTTSPKVNP CCCCCCCCCCCCCCC	24.28	29996109
429	Phosphorylation	RKPLPTTTSPKVNPE CCCCCCCCCCCCCCC	45.57	21712547
430	Phosphorylation	KPLPTTTSPKVNPEP CCCCCCCCCCCCCCC	22.19	21712547
439	Phosphorylation	KVNPEPHSESISDTR CCCCCCCCCCCCCCC	43.70	21712547
441	Phosphorylation	NPEPHSESISDTRPS CCCCCCCCCCCCCCC	30.33	21712547
443	Phosphorylation	EPHSESISDTRPSTP CCCCCCCCCCCCCCC	42.06	29996109
445	Phosphorylation	HSESISDTRPSTPRK CCCCCCCCCCCCCCC	37.37	21712547
448	Phosphorylation	SISDTRPSTPRKVPP CCCCCCCCCCCCCCC	47.99	28889911
449	Phosphorylation	ISDTRPSTPRKVPPS CCCCCCCCCCCCCCC	29.78	24763107
470	Phosphorylation	PKLQGGNSVTAPSTP CCCCCCCCCCCCCCC	24.91	25720772
472	Phosphorylation	LQGGNSVTAPSTPSK CCCCCCCCCCCCCCC	32.45	24763107
475	Phosphorylation	GNSVTAPSTPSKVLP CCCCCCCCCCCCCCC	50.95	21712547
476	Phosphorylation	NSVTAPSTPSKVLPA CCCCCCCCCCCCCCC	30.44	29996109
478	Phosphorylation	VTAPSTPSKVLPAMS CCCCCCCCCCCCCCC	35.17	21712547
485	Phosphorylation	SKVLPAMSPKVAPKF CCCCCCCCCCCCCCC	24.55	24763107
497	Phosphorylation	PKFQGGRSSTAPSTP CCCCCCCCCCCCCCC	35.00	24763107
498	Phosphorylation	KFQGGRSSTAPSTPN CCCCCCCCCCCCCCC	27.51	21712547
499	Phosphorylation	FQGGRSSTAPSTPNK CCCCCCCCCCCCCCC	43.78	21712547
502	Phosphorylation	GRSSTAPSTPNKVLP CCCCCCCCCCCCCCC	54.77	25720772
503	Phosphorylation	RSSTAPSTPNKVLPA CCCCCCCCCCCCCCH	29.80	21712547
525	Phosphorylation	KLQEKAASFDIPNKS HHHHHHHHCCCCCCC	28.45	28889911
536	Phosphorylation	PNKSTIISTKSTVAS CCCCEEEECCCCCCC	26.40	25720772
537	Phosphorylation	NKSTIISTKSTVASP CCCEEEECCCCCCCC	20.71	21712547
539	Phosphorylation	STIISTKSTVASPIK CEEEECCCCCCCCCC	28.36	24763107
540	Phosphorylation	TIISTKSTVASPIKA EEEECCCCCCCCCCC	22.96	21712547
543	Phosphorylation	STKSTVASPIKANEN ECCCCCCCCCCCCCC	23.87	28889911
551	Phosphorylation	PIKANENSPALKSKA CCCCCCCCHHHHCCC	12.84	29996109
556	Phosphorylation	ENSPALKSKASFEFP CCCHHHHCCCCEECC	34.01	21712547
559	Phosphorylation	PALKSKASFEFPKEL HHHHCCCCEECCCCC	29.10	28889911
879	Phosphorylation	YVELMQQYVRPSLTN HHHHHHHHHCHHHCC	4.99	27738172
883	Phosphorylation	MQQYVRPSLTNRSSS HHHHHCHHHCCCCCC	36.94	21712547
885	Phosphorylation	QYVRPSLTNRSSSPT HHHCHHHCCCCCCCC	32.68	21712547
888	Phosphorylation	RPSLTNRSSSPTVTP CHHHCCCCCCCCCCC	36.92	28889911
889	Phosphorylation	PSLTNRSSSPTVTPT HHHCCCCCCCCCCCC	36.78	29996109
890	Phosphorylation	SLTNRSSSPTVTPTV HHCCCCCCCCCCCCC	26.32	28889911
892	Phosphorylation	TNRSSSPTVTPTVNT CCCCCCCCCCCCCCC	38.67	25720772
894	Phosphorylation	RSSSPTVTPTVNTDR CCCCCCCCCCCCCCC	18.73	25720772
896	Phosphorylation	SSPTVTPTVNTDRQP CCCCCCCCCCCCCCC	19.61	29996109
899	Phosphorylation	TVTPTVNTDRQPKTL CCCCCCCCCCCCCCC	28.37	29996109
907	Phosphorylation	DRQPKTLTNSADELS CCCCCCCCCCHHHCC	32.15	29996109
909	Phosphorylation	QPKTLTNSADELSPQ CCCCCCCCHHHCCCC	31.68	28889911
914	Phosphorylation	TNSADELSPQKRRVE CCCHHHCCCCCCCCC	24.20	28889911
934	Phosphorylation	VKDEGPVSIVEDEES CCCCCCCEEECCCCC	24.85	24763107
951	Phosphorylation	VVTKKEDSIPVAQST EECCCCCCCCHHHCC	29.86	21712547
957	Phosphorylation	DSIPVAQSTKADAGL CCCCHHHCCCCCCCC	23.34	24763107
958	Phosphorylation	SIPVAQSTKADAGLD CCCHHHCCCCCCCCC	20.40	21712547
974	Phosphorylation	ENDLLPKSGSGVSET CCCCCCCCCCCCCCC	35.93	25720772
976	Phosphorylation	DLLPKSGSGVSETPA CCCCCCCCCCCCCCC	43.01	29996109
979	Phosphorylation	PKSGSGVSETPAFSH CCCCCCCCCCCCCCC	39.00	29996109
981	Phosphorylation	SGSGVSETPAFSHAR CCCCCCCCCCCCCCC	16.65	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YJX4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YJX4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YJX4_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YJX4_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-525; SER-559; SER-888AND SER-890, AND MASS SPECTROMETRY.
PubMed: 18257517