YJU3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YJU3_SCHPO
• UniProt AC: Q9URT2
• Protein Name: Uncharacterized protein P25A2.03
• Gene Name: SPCP25A2.03
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 752
• Protein Sequence: MEVQKGLIEAFYNTYPLEKAKELDKSPLCSEYELFIKELWPSIVESFHNSTEFETAIRFCCYETARKSEIGLEERLKCLFAILDLLVIGNEINESFCDHLLPFLILEELMDIHTVNECAKLYEYFETRPSLMKGIVSNRGRGPVLLRISNELLRRLSRQENSSFCGRIDILLSKAFPPEERSGANLRGDYNTVHSFGKVELSPPSTPISDRTDLSYHKKLNTLFTAYWDLQCMCSNPPKLLASDTLPKFIDAAGSAIQAFESILQNTFFNGKSNPTIDPNSSSLLSEKYITLDKGFPSKYIYSRSLFEYQLSDEDFRLQAILQLIIIFDFLLDHSKERIERRTLEKWTNKAVIPIVILSDEDTSKLNELSKEAYSFLHTARCGSVQRTIKEIIHIEGNWKLWKGLGCPSLEKPLVDKAAIDEAVEGLKKLTNTPVKLRFAMGNAALSRLWEQAGENTLDDLKKEERYRIPSPESFLSGVKADKFEIEEAVRDDDKHFHEQSLATKTWRAFRSAINSHLQNFSDTGLGDVELLCNSIEGKPTTSKITPSIPPAFDIHIIEGEELLEEMKKRENVKHNSQNFASPMQTDAEGDIVQNEEEKESVEVEEGKHKNDLPKVSPKPPTEGVDSEVNGESLVQVNKVLKSEDDNTSEASKDPSSHVKSPENIEKLKQNDDHFEVTEEITSTINSKISEKQENNVAETILEVTSSPKSSENSQKQSEITKKRGRDEEDEPSDLHSSPKRPKTGEDGEIVL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
202	Phosphorylation	SFGKVELSPPSTPIS CCEEEEECCCCCCCC	22.66	28889911
205	Phosphorylation	KVELSPPSTPISDRT EEEECCCCCCCCCCC	50.64	21712547
206	Phosphorylation	VELSPPSTPISDRTD EEECCCCCCCCCCCC	30.34	28889911
471	Phosphorylation	EERYRIPSPESFLSG HHHHCCCCHHHHHHC	38.64	25720772
477	Phosphorylation	PSPESFLSGVKADKF CCHHHHHHCCCCCCE	39.26	25720772
577	Phosphorylation	RENVKHNSQNFASPM HHCCCCCCCCCCCCC	26.64	21712547
582	Phosphorylation	HNSQNFASPMQTDAE CCCCCCCCCCCCCCC	19.43	28889911
586	Phosphorylation	NFASPMQTDAEGDIV CCCCCCCCCCCCCCC	30.81	24763107
643	Phosphorylation	QVNKVLKSEDDNTSE EHHHEECCCCCCCCC	41.94	24763107
648	Phosphorylation	LKSEDDNTSEASKDP ECCCCCCCCCHHCCC	34.63	21712547
649	Phosphorylation	KSEDDNTSEASKDPS CCCCCCCCCHHCCCC	37.10	29996109
652	Phosphorylation	DDNTSEASKDPSSHV CCCCCCHHCCCCCCC	33.27	29996109
656	Phosphorylation	SEASKDPSSHVKSPE CCHHCCCCCCCCCHH	43.12	29996109
657	Phosphorylation	EASKDPSSHVKSPEN CHHCCCCCCCCCHHH	37.37	29996109
661	Phosphorylation	DPSSHVKSPENIEKL CCCCCCCCHHHHHHH	36.04	28889911
705	Phosphorylation	AETILEVTSSPKSSE HHHHHHHHCCCCCCC	17.70	29996109
706	Phosphorylation	ETILEVTSSPKSSEN HHHHHHHCCCCCCCC	50.23	28889911
707	Phosphorylation	TILEVTSSPKSSENS HHHHHHCCCCCCCCH	27.29	28889911
710	Phosphorylation	EVTSSPKSSENSQKQ HHHCCCCCCCCHHHH	46.39	25720772
711	Phosphorylation	VTSSPKSSENSQKQS HHCCCCCCCCHHHHH	47.09	25720772
733	Phosphorylation	RDEEDEPSDLHSSPK CCCCCCCCCCCCCCC	51.24	21712547
737	Phosphorylation	DEPSDLHSSPKRPKT CCCCCCCCCCCCCCC	56.48	24763107
738	Phosphorylation	EPSDLHSSPKRPKTG CCCCCCCCCCCCCCC	24.56	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YJU3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YJU3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YJU3_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YJU3_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-202; SER-582; SER-707AND SER-738, AND MASS SPECTROMETRY.
PubMed: 18257517