YJD2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YJD2_SCHPO
• UniProt AC: O74505
• Protein Name: Uncharacterized protein C594.02c
• Gene Name: SPCC594.02c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 489
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Sequence: MAPAVFTSDYWKKYFSNKKKPTVKNTSDIDLLHINRGRQPFDEGLSINEDSFFYRHNIHVPRIVYLIIVACGSFIITGGIEFAIAYGMYKKTETSVRLWRLPDTLSGDAAVTNFVQAIVTYWVESILVQGDLRSGLVKPIYFGWWPENFLLREVLRAKPRYHFKFIVFRWMEWLVFVGLRGLVWSVPLWFLFWPATVGILCAPGRHEGNDYYFNNYPAPQVFKLIFGGGEGFVLTPWIAFLHMYMYGHYLHVAKNQKSLPKTSDLEQQRGTSSSQPSENDANITALPKPEPKMYENSDLTPARTPVTPAPLEKPVNLAPEVVEPTNAAASPLQLNAPKLTDVDDSALAYDPTKVQDGEDRFVHNDVPLENAENPSRFVHSDAPIDMTHTTTVISEAQNLPSTLLPQDGNAVHHDTDAPSLSNVRKSVDSPRVPPSFSDDAVSSFSLVTAPSINNVGGSTAPSVNNQEREYDYDDTSSRSSTLTERPVVH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	KKPTVKNTSDIDLLH CCCCCCCCCCCCEEE	23.27	28889911
27	Phosphorylation	KPTVKNTSDIDLLHI CCCCCCCCCCCEEEE	41.80	28889911
46	Phosphorylation	QPFDEGLSINEDSFF CCCCCCCCCCCCCHH	33.94	28889911
258	Phosphorylation	HVAKNQKSLPKTSDL HHHHCCCCCCCCCCH	39.89	29996109
262	Phosphorylation	NQKSLPKTSDLEQQR CCCCCCCCCCHHHHC	26.07	28889911
263	Phosphorylation	QKSLPKTSDLEQQRG CCCCCCCCCHHHHCC	46.45	28889911
271	Phosphorylation	DLEQQRGTSSSQPSE CHHHHCCCCCCCCCC	27.85	29996109
272	Phosphorylation	LEQQRGTSSSQPSEN HHHHCCCCCCCCCCC	30.71	28889911
273	Phosphorylation	EQQRGTSSSQPSEND HHHCCCCCCCCCCCC	32.60	21712547
274	Phosphorylation	QQRGTSSSQPSENDA HHCCCCCCCCCCCCC	45.97	24763107
277	Phosphorylation	GTSSSQPSENDANIT CCCCCCCCCCCCCCC	41.20	24763107
294	Phosphorylation	PKPEPKMYENSDLTP CCCCCCCCCCCCCCC	20.34	25720772
297	Phosphorylation	EPKMYENSDLTPART CCCCCCCCCCCCCCC	23.27	24763107
300	Phosphorylation	MYENSDLTPARTPVT CCCCCCCCCCCCCCC	21.64	21712547
304	Phosphorylation	SDLTPARTPVTPAPL CCCCCCCCCCCCCCC	24.98	24763107
307	Phosphorylation	TPARTPVTPAPLEKP CCCCCCCCCCCCCCC	18.22	24763107
325	Phosphorylation	APEVVEPTNAAASPL CCCCCCCCCCCCCCC	24.80	29996109
330	Phosphorylation	EPTNAAASPLQLNAP CCCCCCCCCCCCCCC	22.78	21712547
462	Phosphorylation	VGGSTAPSVNNQERE CCCCCCCCCCCCCCE	34.71	29996109
475	Phosphorylation	REYDYDDTSSRSSTL CEECCCCCCCCCCCC	26.21	25720772
476	Phosphorylation	EYDYDDTSSRSSTLT EECCCCCCCCCCCCC	30.65	25720772
477	Phosphorylation	YDYDDTSSRSSTLTE ECCCCCCCCCCCCCC	37.97	25720772
479	Phosphorylation	YDDTSSRSSTLTERP CCCCCCCCCCCCCCC	29.62	25720772
480	Phosphorylation	DDTSSRSSTLTERPV CCCCCCCCCCCCCCC	26.73	25720772
481	Phosphorylation	DTSSRSSTLTERPVV CCCCCCCCCCCCCCC	38.66	28889911
483	Phosphorylation	SSRSSTLTERPVVH- CCCCCCCCCCCCCC-	30.00	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YJD2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YJD2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YJD2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YJD2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-26; SER-27 AND SER-263,AND MASS SPECTROMETRY.
PubMed: 18257517